CL2019002503A1 - Compuesto de sulfamida cíclico y métodos de uso de los mismo. - Google Patents
Compuesto de sulfamida cíclico y métodos de uso de los mismo.Info
- Publication number
- CL2019002503A1 CL2019002503A1 CL2019002503A CL2019002503A CL2019002503A1 CL 2019002503 A1 CL2019002503 A1 CL 2019002503A1 CL 2019002503 A CL2019002503 A CL 2019002503A CL 2019002503 A CL2019002503 A CL 2019002503A CL 2019002503 A1 CL2019002503 A1 CL 2019002503A1
- Authority
- CL
- Chile
- Prior art keywords
- methods
- sulfonamide compound
- cyclic sulfonamide
- cyclic
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762465986P | 2017-03-02 | 2017-03-02 | |
| US201762529874P | 2017-07-07 | 2017-07-07 | |
| US201762549728P | 2017-08-24 | 2017-08-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2019002503A1 true CL2019002503A1 (es) | 2020-05-15 |
Family
ID=61692082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2019002503A CL2019002503A1 (es) | 2017-03-02 | 2019-08-30 | Compuesto de sulfamida cíclico y métodos de uso de los mismo. |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11078170B2 (es) |
| EP (1) | EP3589630B1 (es) |
| JP (1) | JP2020511436A (es) |
| KR (1) | KR20190126102A (es) |
| CN (1) | CN110621672A (es) |
| AU (1) | AU2018227811A1 (es) |
| BR (1) | BR112019018230A2 (es) |
| CA (1) | CA3055194A1 (es) |
| CL (1) | CL2019002503A1 (es) |
| DO (1) | DOP2019000225A (es) |
| ES (1) | ES2898217T3 (es) |
| IL (1) | IL269037A (es) |
| MX (1) | MX2019010404A (es) |
| PH (1) | PH12019502003A1 (es) |
| SG (1) | SG11201908012SA (es) |
| TW (1) | TW201840545A (es) |
| WO (1) | WO2018160878A1 (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017326356A1 (en) | 2016-09-15 | 2019-04-11 | Assembly Biosciences, Inc. | Hepatitis B core protein modulators |
| ES2898217T3 (es) * | 2017-03-02 | 2022-03-04 | Assembly Biosciences Inc | Compuestos de sulfamida cíclica y métodos de uso de los mismos |
| BR112020008765A2 (pt) | 2017-11-02 | 2020-10-20 | Aicuris Gmbh & Co. Kg | indol-2-carboxamidas pirazolo-piperidina substituídas altamente ativas inovadoras ativas contra o vírus da hepatite b (hbv) |
| WO2019086141A1 (en) | 2017-11-02 | 2019-05-09 | Aicuris Gmbh & Co. Kg | Novel, highly active amino-thiazole substituted indole-2-carboxamides active against the hepatitis b virus (hbv) |
| HU231414B1 (hu) * | 2018-07-13 | 2023-08-28 | Richter Gedeon Nyrt. | Tiadiazin származékok |
| CN113164493A (zh) * | 2018-09-05 | 2021-07-23 | 组装生物科学股份有限公司 | 用于治疗hbv的环状磺酰胺化合物 |
| US20220081433A1 (en) * | 2018-09-05 | 2022-03-17 | Assembly Biosciences, Inc. | Cyclic sulfamide compounds for treatment of hbv |
| SG11202104132WA (en) | 2018-11-02 | 2021-05-28 | Aicuris Gmbh & Co Kg | Novel urea 6,7-dihydro-4h-thiazolo[5,4-c]pyridines active against the hepatitis b virus (hbv) |
| UY38437A (es) | 2018-11-02 | 2020-05-29 | Aicuris Gmbh & Co Kg | Nuevas urea 6,7-dihidro-4h-pirazolo[1,5-a]pirazinas activas contra el virus de la hepatitis b (hbv) |
| AR116946A1 (es) | 2018-11-02 | 2021-06-30 | Aicuris Gmbh & Co Kg | Derivados de urea 6,7-dihidro-4h-pirazolo[4,3-c]piridinas activas contra el virus de la hepatitis b (vhb) |
| UY38434A (es) | 2018-11-02 | 2020-05-29 | Aicuris Gmbh & Co Kg | Nuevas 6,7-dihidro-4h-pirazolo[1,5-a]pirazin indol-2-carboxamidas activas contra el virus de la hepatitis b (hbv) |
| AR116947A1 (es) | 2018-11-02 | 2021-06-30 | Aicuris Gmbh & Co Kg | Derivados de urea 6,7-dihidro-4h-pirazolo[1,5-a]pirazinas-indol-2-carboxamidas activas contra el virus de la hepatitis b (vhb) |
| UY38435A (es) | 2018-11-02 | 2020-05-29 | Aicuris Gmbh & Co Kg | Nuevas urea 6,7-dihidro-4h-pirazol[1,5-a] pirazinas activas contra el virus de la hepatitis b (vhb) |
| EP3962909B1 (en) | 2019-04-30 | 2023-10-04 | AiCuris GmbH & Co. KG | Novel oxalyl piperazines active against the hepatitis b virus (hbv) |
| WO2020221826A1 (en) | 2019-04-30 | 2020-11-05 | Aicuris Gmbh & Co. Kg | Novel indole-2-carboxamides active against the hepatitis b virus (hbv) |
| SG11202111198QA (en) | 2019-04-30 | 2021-11-29 | Aicuris Gmbh & Co Kg | Novel indolizine-2-carboxamides active against the hepatitis b virus (hbv) |
| JP2022531199A (ja) | 2019-04-30 | 2022-07-06 | アイクリス ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | Ｂ型肝炎ウイルス（ｈｂｖ）に対し活性な新規のフェニル及びピリジル尿素 |
| WO2021065898A1 (ja) | 2019-09-30 | 2021-04-08 | 日本ケミファ株式会社 | アゼパン誘導体 |
| JP2022554392A (ja) * | 2019-11-05 | 2022-12-28 | デルミラ インコーポレイテッド | ＭｒｇｐｒＸ２アンタゴニストおよびその使用 |
| WO2021092554A1 (en) * | 2019-11-08 | 2021-05-14 | Assembly Biosciences, Inc. | Pharmaceutical compositions and methods for treating hbv disorders |
| CN115702152A (zh) * | 2020-04-22 | 2023-02-14 | 南京明德新药研发有限公司 | 内磺酰胺衍生物及其应用 |
| WO2022233305A1 (zh) * | 2021-05-07 | 2022-11-10 | 南京明德新药研发有限公司 | 甲基磺酰脲类化合物及其应用 |
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| US3223703A (en) * | 1963-08-01 | 1965-12-14 | Upjohn Co | 3-carbalkoxy- and 3-carbamoyl-5-subtituted - (2h) - 1,2,6 - thiadiazine - 1,1-dioxides and process |
| GB1480553A (en) | 1976-06-03 | 1977-07-20 | Pfizer Ltd | Tricyclic sulphonamides |
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| US6927216B2 (en) * | 2000-10-03 | 2005-08-09 | Bristol-Myers Squibb Pharma Company | Cyclic sulfonyl compounds as inhibitors of metalloproteases |
| DE10109856A1 (de) * | 2001-03-01 | 2002-09-05 | Bayer Ag | Arzneimittel gegen virale Erkrankungen |
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| US20070105835A1 (en) | 2005-11-07 | 2007-05-10 | Kazantsev Aleksey G | Compositions and methods for modulating poly(ADP-ribose) polymerase activity |
| JP4042065B1 (ja) | 2006-03-10 | 2008-02-06 | 健治 吉田 | 情報処理装置への入力処理システム |
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| AU2013307328B2 (en) | 2012-08-28 | 2017-10-19 | Janssen Sciences Ireland Uc | Fused bicyclic sulfamoyl derivatives and the use thereof as medicaments for the treatment of hepatitis B |
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| RU2519546C1 (ru) | 2013-01-16 | 2014-06-10 | Общество С Ограниченной Ответственностью "Биоинтегратор" (Ооо "Биоинтегратор") | КОНЪЮГАТЫ И МАЛЫЕ МОЛЕКУЛЫ, ВЗАИМОДЕЙСТВУЮЩИЕ С РЕЦЕПТОРОМ CD16а |
| DK2961732T3 (en) | 2013-02-28 | 2017-07-10 | Janssen Sciences Ireland Uc | SULFAMOYLARYLAMIDS AND USE THEREOF AS MEDICINES TO TREAT HEPATITIS B |
| AR095426A1 (es) | 2013-03-14 | 2015-10-14 | Onyx Therapeutics Inc | Inhibidores tripeptídicos de la epoxicetona proteasa |
| UA120248C2 (uk) | 2013-03-15 | 2019-11-11 | Селджен Кар Ллс | Гетероарильні сполуки та їх застосування |
| WO2014161888A1 (en) | 2013-04-03 | 2014-10-09 | Janssen R&D Ireland | N-phenyl-carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b |
| JO3603B1 (ar) | 2013-05-17 | 2020-07-05 | Janssen Sciences Ireland Uc | مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي |
| LT2997019T (lt) | 2013-05-17 | 2018-11-26 | Janssen Sciences Ireland Uc | Sulfamoiltiofenamido dariniai ir jų panaudojimas kaip vaistų hepatito b gydymui |
| AU2014267198A1 (en) | 2013-05-17 | 2015-11-05 | F. Hoffmann-La Roche Ag | 6-bridged heteroaryldihydropyrimidines for the treatment and prophylaxis of Hepatitis B virus infection |
| EP3010501B1 (en) | 2013-06-19 | 2021-11-03 | Seragon Pharmaceuticals, Inc. | Estrogen receptor modulator and uses thereof |
| EP3027612B1 (en) | 2013-07-29 | 2018-10-10 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | 11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepine s-oxide derivatives and their use as dopamine d2 receptor antagonists |
| MX363600B (es) | 2014-03-13 | 2019-03-28 | Univ Indiana Res & Tech Corp | Moduladores alostericos de proteina nucleo de hepatitis b. |
| US10328082B2 (en) * | 2014-05-30 | 2019-06-25 | Pfizer Inc. | Methods of use and combinations |
| WO2015189035A1 (en) | 2014-06-10 | 2015-12-17 | Basf Se | Substituted [1,2,4]triazole and imidazole compounds as fungicides |
| TWI721016B (zh) | 2015-09-15 | 2021-03-11 | 美商艾森伯利生物科學公司 | B型肝炎核心蛋白質調節劑 |
| AU2017326356A1 (en) | 2016-09-15 | 2019-04-11 | Assembly Biosciences, Inc. | Hepatitis B core protein modulators |
| ES2898217T3 (es) | 2017-03-02 | 2022-03-04 | Assembly Biosciences Inc | Compuestos de sulfamida cíclica y métodos de uso de los mismos |
| CN110612300B (zh) | 2017-03-13 | 2023-10-20 | 组装生物科学股份有限公司 | 制备乙型肝炎核心蛋白调节剂的方法 |
-
2018
- 2018-03-01 ES ES18712322T patent/ES2898217T3/es active Active
- 2018-03-01 KR KR1020197028756A patent/KR20190126102A/ko not_active Application Discontinuation
- 2018-03-01 MX MX2019010404A patent/MX2019010404A/es unknown
- 2018-03-01 CN CN201880028308.3A patent/CN110621672A/zh active Pending
- 2018-03-01 WO PCT/US2018/020515 patent/WO2018160878A1/en unknown
- 2018-03-01 JP JP2019547716A patent/JP2020511436A/ja active Pending
- 2018-03-01 AU AU2018227811A patent/AU2018227811A1/en not_active Abandoned
- 2018-03-01 CA CA3055194A patent/CA3055194A1/en not_active Abandoned
- 2018-03-01 SG SG11201908012SA patent/SG11201908012SA/en unknown
- 2018-03-01 BR BR112019018230-6A patent/BR112019018230A2/pt not_active Application Discontinuation
- 2018-03-01 US US16/490,223 patent/US11078170B2/en active Active
- 2018-03-01 EP EP18712322.9A patent/EP3589630B1/en active Active
- 2018-03-02 TW TW107107115A patent/TW201840545A/zh unknown
-
2019
- 2019-08-30 CL CL2019002503A patent/CL2019002503A1/es unknown
- 2019-09-01 IL IL26903719A patent/IL269037A/en unknown
- 2019-09-02 PH PH12019502003A patent/PH12019502003A1/en unknown
- 2019-09-02 DO DO2019000225A patent/DOP2019000225A/es unknown
-
2021
- 2021-01-14 US US17/149,486 patent/US20230012463A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DOP2019000225A (es) | 2019-12-15 |
| JP2020511436A (ja) | 2020-04-16 |
| IL269037A (en) | 2019-10-31 |
| US11078170B2 (en) | 2021-08-03 |
| MX2019010404A (es) | 2019-11-21 |
| AU2018227811A1 (en) | 2019-09-19 |
| WO2018160878A1 (en) | 2018-09-07 |
| KR20190126102A (ko) | 2019-11-08 |
| TW201840545A (zh) | 2018-11-16 |
| PH12019502003A1 (en) | 2020-06-15 |
| SG11201908012SA (en) | 2019-09-27 |
| US20230012463A1 (en) | 2023-01-12 |
| ES2898217T3 (es) | 2022-03-04 |
| CA3055194A1 (en) | 2018-09-07 |
| EP3589630A1 (en) | 2020-01-08 |
| EP3589630B1 (en) | 2021-07-07 |
| CN110621672A (zh) | 2019-12-27 |
| BR112019018230A2 (pt) | 2020-07-21 |
| US20200157070A1 (en) | 2020-05-21 |
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