CL2018001548A1 - Tratamiento de colestasis intrahepática y enfermedades del hígado relacionadas - Google Patents
Tratamiento de colestasis intrahepática y enfermedades del hígado relacionadasInfo
- Publication number
- CL2018001548A1 CL2018001548A1 CL2018001548A CL2018001548A CL2018001548A1 CL 2018001548 A1 CL2018001548 A1 CL 2018001548A1 CL 2018001548 A CL2018001548 A CL 2018001548A CL 2018001548 A CL2018001548 A CL 2018001548A CL 2018001548 A1 CL2018001548 A1 CL 2018001548A1
- Authority
- CL
- Chile
- Prior art keywords
- treatment
- liver diseases
- subject
- intrahepatic cholestasis
- related liver
- Prior art date
Links
- 208000001024 intrahepatic cholestasis Diseases 0.000 title 1
- 230000007872 intrahepatic cholestasis Effects 0.000 title 1
- 208000019423 liver disease Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 206010008635 Cholestasis Diseases 0.000 abstract 2
- 230000007870 cholestasis Effects 0.000 abstract 2
- 231100000359 cholestasis Toxicity 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 239000003613 bile acid Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000006345 epimerization reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/733—Fructosans, e.g. inulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LA INVENCIÓN SE DIRIGE A UN MÉTODO PARA TRATAR O REDUCIR EL RIESGO DE COLESTASIS INTRAHEPÁTICA EN UN SUJETO EN NECESIDAD, QUE COMPRENDE ADMINISTRAR AL SUJETO UNA CANTIDAD TERAPÉUTICAMENTE EFICAZ DE UNA COMPOSICIÓN QUE COMPRENDE AL MENOS UNA ESPECIE O CEPA BACTERIANA QUE COMPRENDE LA ACTIVIDAD DE DESCONJUGACIÓN/HIDRÓLISIS DEL ÁCIDO BILIAR Y/O ACTIVIDAD DE 7- EPIMERIZACIÓN, TRATANDO DE ESTE MODO O REDUCIENDO EL RIESGO DE COLESTASIS INTRAHEPÁTICA EN UN SUJETO EN NECESIDAD; TAMBIÉN SE PROPORCIONAN LAS COMPOSICIONES PARA USO EN DICHOS MÉTODOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562266771P | 2015-12-14 | 2015-12-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2018001548A1 true CL2018001548A1 (es) | 2018-07-20 |
Family
ID=57570064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2018001548A CL2018001548A1 (es) | 2015-12-14 | 2018-06-11 | Tratamiento de colestasis intrahepática y enfermedades del hígado relacionadas |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20180369297A1 (es) |
| EP (1) | EP3389680B1 (es) |
| JP (2) | JP2018537484A (es) |
| KR (1) | KR20180094950A (es) |
| CN (1) | CN109069548A (es) |
| AU (1) | AU2016374365B2 (es) |
| BR (1) | BR112018012022A2 (es) |
| CA (1) | CA3008195A1 (es) |
| CL (1) | CL2018001548A1 (es) |
| ES (1) | ES2962302T3 (es) |
| IL (1) | IL259480B2 (es) |
| MX (1) | MX2018007227A (es) |
| RU (1) | RU2743405C2 (es) |
| SG (1) | SG11201804255QA (es) |
| WO (1) | WO2017102816A1 (es) |
| ZA (1) | ZA201804660B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8906668B2 (en) | 2012-11-23 | 2014-12-09 | Seres Health, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
| EP2967077A4 (en) | 2013-03-15 | 2016-09-14 | Seres Therapeutics Inc | MICROBIAL COMPOSITIONS AND ASSOCIATED METHODS BASED ON A NETWORK |
| GB2551642B (en) | 2014-10-31 | 2020-09-23 | Pendulum Therapeutics Inc | Methods and compositions relating to microbial treatment and diagnosis of disorders |
| RU2020110462A (ru) * | 2017-08-14 | 2021-09-16 | Серес Терапеутикс, Инк. | Композиции и способы для лечения холестатического заболевания |
| WO2019046646A1 (en) | 2017-08-30 | 2019-03-07 | Whole Biome Inc. | METHODS AND COMPOSITIONS FOR THE TREATMENT OF MICROBIOMA ASSOCIATED DISORDERS |
| CN112280720B (zh) * | 2020-11-19 | 2021-07-13 | 山东龙昌动物保健品有限公司 | 一株多形拟杆菌gl-02及其与胆汁酸复配的复合菌剂与应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1283225B1 (it) * | 1996-03-11 | 1998-04-16 | Renata Maria Anna Ve Cavaliere | Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle |
| CA2374937A1 (en) * | 1999-05-25 | 2000-11-30 | Gregor Reid | Oral administration of lactobacillus for the maintenance of health in women |
| AUPQ899700A0 (en) * | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| ES2381211T3 (es) * | 2006-02-15 | 2012-05-24 | Nestec S.A. | Uso del Bifidobacterium longum para prevenir y tratar inflamaciones |
| EP2432484A1 (en) * | 2009-04-30 | 2012-03-28 | Compagnie Gervais Danone | Use of collinsella aerofaciens for reducing bloating |
| CN102539791A (zh) * | 2012-01-09 | 2012-07-04 | 宁波天康生物科技有限公司 | 总胆汁酸的定量测定及测定试剂盒 |
| CA2926466C (en) * | 2013-10-03 | 2021-11-16 | Frederic Bushman | Compositions comprising a defined microbiome and methods of use thereof |
-
2016
- 2016-12-14 SG SG11201804255QA patent/SG11201804255QA/en unknown
- 2016-12-14 AU AU2016374365A patent/AU2016374365B2/en not_active Expired - Fee Related
- 2016-12-14 MX MX2018007227A patent/MX2018007227A/es unknown
- 2016-12-14 RU RU2018124487A patent/RU2743405C2/ru active
- 2016-12-14 US US15/781,595 patent/US20180369297A1/en active Pending
- 2016-12-14 CA CA3008195A patent/CA3008195A1/en active Pending
- 2016-12-14 ES ES16812728T patent/ES2962302T3/es active Active
- 2016-12-14 CN CN201680073160.6A patent/CN109069548A/zh active Pending
- 2016-12-14 JP JP2018530858A patent/JP2018537484A/ja active Pending
- 2016-12-14 KR KR1020187019268A patent/KR20180094950A/ko not_active Application Discontinuation
- 2016-12-14 BR BR112018012022-7A patent/BR112018012022A2/pt active Search and Examination
- 2016-12-14 WO PCT/EP2016/080941 patent/WO2017102816A1/en active Application Filing
- 2016-12-14 EP EP16812728.0A patent/EP3389680B1/en active Active
- 2016-12-14 IL IL259480A patent/IL259480B2/en unknown
-
2018
- 2018-06-11 CL CL2018001548A patent/CL2018001548A1/es unknown
- 2018-07-12 ZA ZA2018/04660A patent/ZA201804660B/en unknown
-
2022
- 2022-07-28 JP JP2022120558A patent/JP2022166039A/ja not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL259480B1 (en) | 2023-05-01 |
| BR112018012022A2 (pt) | 2018-12-04 |
| EP3389680A1 (en) | 2018-10-24 |
| WO2017102816A1 (en) | 2017-06-22 |
| ES2962302T3 (es) | 2024-03-18 |
| EP3389680B1 (en) | 2023-10-11 |
| KR20180094950A (ko) | 2018-08-24 |
| JP2022166039A (ja) | 2022-11-01 |
| IL259480B2 (en) | 2023-09-01 |
| RU2018124487A (ru) | 2020-01-10 |
| ZA201804660B (en) | 2022-12-21 |
| CN109069548A (zh) | 2018-12-21 |
| AU2016374365B2 (en) | 2023-04-13 |
| AU2016374365A1 (en) | 2018-07-12 |
| JP2018537484A (ja) | 2018-12-20 |
| RU2018124487A3 (es) | 2020-05-29 |
| IL259480A (en) | 2018-07-31 |
| EP3389680C0 (en) | 2023-10-11 |
| MX2018007227A (es) | 2018-08-01 |
| CA3008195A1 (en) | 2017-06-22 |
| RU2743405C2 (ru) | 2021-02-18 |
| US20180369297A1 (en) | 2018-12-27 |
| SG11201804255QA (en) | 2018-06-28 |
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