CL2016000025A1 - Volasertib en combinación con azacitidina para el tratamiento de leucemia mieloide aguda y síndrome mielodisplásico. - Google Patents
Volasertib en combinación con azacitidina para el tratamiento de leucemia mieloide aguda y síndrome mielodisplásico.Info
- Publication number
- CL2016000025A1 CL2016000025A1 CL2016000025A CL2016000025A CL2016000025A1 CL 2016000025 A1 CL2016000025 A1 CL 2016000025A1 CL 2016000025 A CL2016000025 A CL 2016000025A CL 2016000025 A CL2016000025 A CL 2016000025A CL 2016000025 A1 CL2016000025 A1 CL 2016000025A1
- Authority
- CL
- Chile
- Prior art keywords
- volasertib
- azacitidine
- treatment
- combination
- myeloid leukemia
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361858804P | 2013-07-26 | 2013-07-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2016000025A1 true CL2016000025A1 (es) | 2016-09-30 |
Family
ID=51228430
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2016000025A CL2016000025A1 (es) | 2013-07-26 | 2016-01-07 | Volasertib en combinación con azacitidina para el tratamiento de leucemia mieloide aguda y síndrome mielodisplásico. |
Country Status (12)
Country | Link |
---|---|
US (3) | US20150031643A1 (es) |
EP (1) | EP3024488A1 (es) |
JP (1) | JP2016525531A (es) |
KR (1) | KR20160035067A (es) |
CN (1) | CN105407923A (es) |
AU (1) | AU2014295019A1 (es) |
CA (1) | CA2919296A1 (es) |
CL (1) | CL2016000025A1 (es) |
EA (1) | EA201600134A1 (es) |
MX (1) | MX2016001087A (es) |
PH (1) | PH12016500083A1 (es) |
WO (1) | WO2015011235A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3661559A1 (en) * | 2017-08-01 | 2020-06-10 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Combination of midh1 inhibitors and dna hypomethylating agents (hma) |
JP2021511352A (ja) * | 2018-01-25 | 2021-05-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 急性骨髄性白血病の併用処置 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060058311A1 (en) * | 2004-08-14 | 2006-03-16 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation |
US20060063735A1 (en) * | 2004-09-17 | 2006-03-23 | Supergen, Inc. | Salts of 5-azacytidine |
US20070117776A1 (en) * | 2005-11-04 | 2007-05-24 | John Lyons | Low Dose Therapy Of DNA Methylation Inhibitors |
US9358233B2 (en) * | 2010-11-29 | 2016-06-07 | Boehringer Ingelheim International Gmbh | Method for treating acute myeloid leukemia |
MY176125A (en) * | 2011-11-03 | 2020-07-24 | Takeda Pharmaceuticals Co | Administration of nedd8-activating enzyme inhibitor and hypomethylating agent |
-
2014
- 2014-07-24 US US14/340,028 patent/US20150031643A1/en not_active Abandoned
- 2014-07-24 CA CA2919296A patent/CA2919296A1/en not_active Abandoned
- 2014-07-24 MX MX2016001087A patent/MX2016001087A/es unknown
- 2014-07-24 CN CN201480041932.9A patent/CN105407923A/zh active Pending
- 2014-07-24 KR KR1020167005131A patent/KR20160035067A/ko not_active Application Discontinuation
- 2014-07-24 WO PCT/EP2014/065938 patent/WO2015011235A1/en active Application Filing
- 2014-07-24 EP EP14744310.5A patent/EP3024488A1/en not_active Ceased
- 2014-07-24 AU AU2014295019A patent/AU2014295019A1/en not_active Abandoned
- 2014-07-24 JP JP2016528535A patent/JP2016525531A/ja active Pending
- 2014-07-24 EA EA201600134A patent/EA201600134A1/ru unknown
-
2016
- 2016-01-07 CL CL2016000025A patent/CL2016000025A1/es unknown
- 2016-01-12 PH PH12016500083A patent/PH12016500083A1/en unknown
-
2017
- 2017-02-24 US US15/441,415 patent/US20170157158A1/en not_active Abandoned
-
2019
- 2019-04-16 US US16/385,144 patent/US20190240242A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR20160035067A (ko) | 2016-03-30 |
CN105407923A (zh) | 2016-03-16 |
US20150031643A1 (en) | 2015-01-29 |
EA201600134A1 (ru) | 2016-07-29 |
US20170157158A1 (en) | 2017-06-08 |
MX2016001087A (es) | 2016-04-20 |
CA2919296A1 (en) | 2015-01-29 |
JP2016525531A (ja) | 2016-08-25 |
EP3024488A1 (en) | 2016-06-01 |
US20190240242A1 (en) | 2019-08-08 |
AU2014295019A1 (en) | 2015-12-17 |
PH12016500083A1 (en) | 2016-04-18 |
WO2015011235A1 (en) | 2015-01-29 |
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