CL2015002069A1 - Métodos para el uso de compuestos de fenoxipropilamina para tratar la depresión. - Google Patents

Métodos para el uso de compuestos de fenoxipropilamina para tratar la depresión.

Info

Publication number
CL2015002069A1
CL2015002069A1 CL2015002069A CL2015002069A CL2015002069A1 CL 2015002069 A1 CL2015002069 A1 CL 2015002069A1 CL 2015002069 A CL2015002069 A CL 2015002069A CL 2015002069 A CL2015002069 A CL 2015002069A CL 2015002069 A1 CL2015002069 A1 CL 2015002069A1
Authority
CL
Chile
Prior art keywords
methods
treat depression
phenoxypropylamine
phenoxypropylamine compounds
compounds
Prior art date
Application number
CL2015002069A
Other languages
English (en)
Inventor
Lorenzo Pellegrini
Argeris Karabelas
Remy Luthringer
Original Assignee
Minerva Neurosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minerva Neurosciences Inc filed Critical Minerva Neurosciences Inc
Publication of CL2015002069A1 publication Critical patent/CL2015002069A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245Oxadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

METODO PARA TRATAR O DISMINUIR A LO MENOS UN SINTOMA DE LA DEPRESION, QUE COMPRENDE LA ADMINISTRACION DE UN COMPUESTO DERIVADO DE FENOXIPROPILAMINA
CL2015002069A 2013-01-24 2015-07-24 Métodos para el uso de compuestos de fenoxipropilamina para tratar la depresión. CL2015002069A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361756208P 2013-01-24 2013-01-24
US201361852149P 2013-03-15 2013-03-15
US201361799482P 2013-03-15 2013-03-15

Publications (1)

Publication Number Publication Date
CL2015002069A1 true CL2015002069A1 (es) 2016-05-20

Family

ID=51208168

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015002069A CL2015002069A1 (es) 2013-01-24 2015-07-24 Métodos para el uso de compuestos de fenoxipropilamina para tratar la depresión.

Country Status (23)

Country Link
US (2) US20140206722A1 (es)
EP (2) EP3925608A3 (es)
JP (2) JP6422890B2 (es)
KR (4) KR20210047368A (es)
CN (2) CN110664813A (es)
AU (4) AU2014209200B2 (es)
BR (1) BR112015017628A2 (es)
CA (2) CA2898279C (es)
CL (1) CL2015002069A1 (es)
DK (1) DK2948143T3 (es)
ES (1) ES2875058T3 (es)
IL (4) IL311363A (es)
MX (1) MX2015009445A (es)
MY (1) MY185908A (es)
NZ (2) NZ709967A (es)
PE (1) PE20151888A1 (es)
PH (1) PH12015501643B1 (es)
PL (1) PL2948143T3 (es)
PT (1) PT2948143T (es)
RU (2) RU2725112C2 (es)
SG (2) SG11201505737YA (es)
WO (1) WO2014117003A1 (es)
ZA (2) ZA201505114B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201810359PA (en) 2016-05-25 2018-12-28 Mitsubishi Tanabe Pharma Corp (2s)-1-[4-(3,4-dichlorophenyl)piperidin-l-yl]-3-[2-(5-methyl-l,3,4-oxadiazol-2-yl)benzo[b]furan-4-yloxy]propan-2-ol or its metabolite for treating anxiety disorders
US11541201B2 (en) * 2017-10-04 2023-01-03 Neurogeneces, Inc. Sleep performance system and method of use
KR20210061357A (ko) 2018-09-04 2021-05-27 미네르바 뉴로사이언스즈, 인크. 통증을 치료하기 위해 페녹시프로필아민 화합물을 사용하는 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207343A (en) * 1978-06-22 1980-06-10 Eli Lilly And Company 1-Phenyl-3-(substituted phenoxy)propylamines
WO2000071517A1 (fr) * 1999-05-24 2000-11-30 Mitsubishi Pharma Corporation Compose de phenoxypropylamine
ATE266660T1 (de) * 1999-12-20 2004-05-15 Lilly Co Eli Piperidin-derivate und ihre verwendung als serotonin rezeptor antagonisten
RU2424799C1 (ru) * 2010-03-29 2011-07-27 Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ФЕДЕРАЛЬНОГО АГЕНТСТВА ПО ЗДРАВООХРАНЕНИЮ И СОЦИАЛЬНОМУ РАЗВИТИЮ" Способ коррекции депрессивных расстройств производными тиетан-1,1-диоксида в эксперименте

Also Published As

Publication number Publication date
IL287727B1 (en) 2024-04-01
SG10201706035QA (en) 2017-08-30
WO2014117003A1 (en) 2014-07-31
EP2948143A1 (en) 2015-12-02
ES2875058T3 (es) 2021-11-08
EP3925608A2 (en) 2021-12-22
PL2948143T3 (pl) 2021-12-13
MX2015009445A (es) 2016-01-14
PE20151888A1 (es) 2016-01-13
JP2018172400A (ja) 2018-11-08
IL239928B (en) 2021-04-29
AU2014209200A1 (en) 2015-07-30
KR20200086377A (ko) 2020-07-16
US20140206722A1 (en) 2014-07-24
NZ750189A (en) 2020-08-28
US20200223838A1 (en) 2020-07-16
KR102587177B1 (ko) 2023-10-06
MY185908A (en) 2021-06-14
KR20220112865A (ko) 2022-08-11
ZA202207530B (en) 2023-10-25
KR20150120987A (ko) 2015-10-28
SG11201505737YA (en) 2015-08-28
NZ709967A (en) 2020-05-29
CA3150231A1 (en) 2014-07-31
EP3925608A3 (en) 2022-01-19
KR102247960B1 (ko) 2021-05-07
AU2019200512A1 (en) 2019-02-14
AU2019200512B2 (en) 2020-04-16
AU2020205268A1 (en) 2020-08-06
IL287727A (en) 2021-12-01
IL278109B (en) 2022-03-01
RU2020120236A (ru) 2020-09-01
CN105377255A (zh) 2016-03-02
EP2948143B1 (en) 2021-05-05
KR20210047368A (ko) 2021-04-29
AU2020205268B2 (en) 2022-07-07
RU2015135358A (ru) 2017-03-03
PH12015501643A1 (en) 2015-10-12
KR102172351B1 (ko) 2020-11-02
JP2016510331A (ja) 2016-04-07
CN110664813A (zh) 2020-01-10
IL278109A (en) 2020-11-30
JP6657315B2 (ja) 2020-03-04
IL239928A0 (en) 2015-08-31
JP6422890B2 (ja) 2018-11-14
CA2898279A1 (en) 2014-07-31
AU2022241458A1 (en) 2022-10-20
EP2948143A4 (en) 2017-02-22
AU2014209200B2 (en) 2018-11-01
PH12015501643B1 (en) 2015-10-12
PT2948143T (pt) 2021-06-03
BR112015017628A2 (pt) 2017-07-11
CA2898279C (en) 2022-05-17
IL311363A (en) 2024-05-01
DK2948143T3 (da) 2021-07-26
RU2725112C2 (ru) 2020-06-29
ZA201505114B (en) 2023-09-27

Similar Documents

Publication Publication Date Title
SV2018005709A (es) 3-azabiciclo[3.1.0]hexanos sustituidos como inhibidores de cetohexoquinasa
BR112018010118A2 (pt) inibidores de cxcr2
DK3577110T3 (da) 8-oxetan-3-yl-3,8-diazabicyclo[3.2.1]octan-3-yl-substituerede forbindelser som hiv-inhibitorer
CL2018000649A1 (es) Nuevos compuestos bicíclicos como inhibidores duales de atx / ca
CL2016001911A1 (es) Compuesto heterocíclico fusionado
CR20140229A (es) Nuevos derivados bicíclicos de dihidroisoquinolin-1-ona
CL2016000924A1 (es) Mezclas activas como insecticidas, que comprenden un compuesto de carboxamida
CR20160419A (es) Nuevos compuestos biciclicos
CR20180057A (es) Nuevos compuestos biciclicos como inhibidores duales de atx/ca.
CL2015001442A1 (es) Metodo para tratar enfermedades pulmonares que comprende el uso de compuestos derivados del acido obeticolico.
BR112016028476A8 (pt) compostos, composição, uso de um composto e método para o combate dos fungos nocivos
EA201690473A1 (ru) Комбинированный состав двух противовирусных соединений
UY34765A (es) Compuestos novedosos.
BR112016029333A2 (pt) síntese de compostos de carbamoilpiridona policíclico
CL2016001349A1 (es) Uso de derivados de bencimidazol-prolina
GT201500247A (es) Imidazopiridazinas sustituidas
CL2015002837A1 (es) Compuestos de piridinilpirazoloquinolina.
CL2016002338A1 (es) Uso de un compuesto que es ácido r-2-4-2-etoxi-3-4-trifluorometilfenoxipropil-tio-2-metilfenoxi acético, para el tratamiento de una enfermedad colestásica intrahepática .
CL2016000038A1 (es) Piraxolo-piridinaminas sustituidas
CL2015002358A1 (es) Compuestos bicíclicos.
CL2016001095A1 (es) Silicato de zirconio microporoso para el tratamiento de hipercalemia.
CL2017000484A1 (es) Compuestos de azetidiniloxifenilpirrolidina
BR112017013286A2 (pt) composto de isoxazolina, e, uso de um composto de isoxazolina.
CL2014001862A1 (es) Compuestos derivados de morofolinilo sustituido, útiles como inhibidores de mogat-2; composicion farmaceutica que los comprende; uso en el tratamiento de hipertrigliceridemia.
BR112018008006A2 (pt) composto de piranodipiridina