CL2015001237A1 - Anticuerpos anti-receptor de procineticinas (prokr) y usos de los mismos. - Google Patents

Anticuerpos anti-receptor de procineticinas (prokr) y usos de los mismos.

Info

Publication number
CL2015001237A1
CL2015001237A1 CL2015001237A CL2015001237A CL2015001237A1 CL 2015001237 A1 CL2015001237 A1 CL 2015001237A1 CL 2015001237 A CL2015001237 A CL 2015001237A CL 2015001237 A CL2015001237 A CL 2015001237A CL 2015001237 A1 CL2015001237 A1 CL 2015001237A1
Authority
CL
Chile
Prior art keywords
procineticin
prokr
antibodies
receptor
procineticin receptor
Prior art date
Application number
CL2015001237A
Other languages
English (en)
Inventor
Lynn Macdonald
Michael L Lacroix-Fralish
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of CL2015001237A1 publication Critical patent/CL2015001237A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
CL2015001237A 2012-11-13 2015-05-08 Anticuerpos anti-receptor de procineticinas (prokr) y usos de los mismos. CL2015001237A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261725704P 2012-11-13 2012-11-13
US201361825112P 2013-05-20 2013-05-20

Publications (1)

Publication Number Publication Date
CL2015001237A1 true CL2015001237A1 (es) 2015-08-28

Family

ID=49667597

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015001237A CL2015001237A1 (es) 2012-11-13 2015-05-08 Anticuerpos anti-receptor de procineticinas (prokr) y usos de los mismos.

Country Status (18)

Country Link
US (3) US20140134189A1 (es)
EP (1) EP2920211A1 (es)
JP (1) JP2016502520A (es)
KR (1) KR20150084007A (es)
CN (1) CN104781280A (es)
AU (1) AU2013345018A1 (es)
BR (1) BR112015010691A2 (es)
CA (1) CA2891327A1 (es)
CL (1) CL2015001237A1 (es)
CO (1) CO7400866A2 (es)
EA (1) EA201590877A1 (es)
HK (1) HK1210182A1 (es)
IL (1) IL238629A0 (es)
MX (1) MX2015005546A (es)
PH (1) PH12015500903A1 (es)
SG (1) SG11201502933UA (es)
WO (1) WO2014078306A1 (es)
ZA (1) ZA201502516B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI774028B (zh) 2015-01-30 2022-08-11 學校法人埼玉醫科大學 抗alk2抗體及其用途
KR20210133261A (ko) * 2019-02-26 2021-11-05 소렌토 쎄라퓨틱스, 인코포레이티드 Bcma에 결합하는 항원 결합 단백질

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891720A (en) 1997-04-17 1999-04-06 Millennium Pharmaceuticals, Inc. Isolated DNA encoding a novel human G-protein coupled receptor
EP1147136A4 (en) 1998-12-10 2003-04-16 Synaptic Pharma Corp DNA CODED FOR A MAMMAL RECEPTOR (fb41a) AND THEIR USE
US7087411B2 (en) 1999-06-08 2006-08-08 Regeneron Pharmaceuticals, Inc. Fusion protein capable of binding VEGF
NZ518662A (en) 1999-11-17 2004-10-29 Arena Pharm Inc Endogenous and non-endogenous versions of human G protein-coupled receptors
AU2001272735A1 (en) 2000-07-18 2002-01-30 Takeda Chemical Industries Ltd. Novel physiologically active peptide and use thereof
US6902902B2 (en) 2001-11-27 2005-06-07 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders
DE10229379A1 (de) 2002-06-26 2004-01-29 Schering Ag EG-VEGF Rezeptor Antagonisten
AU2003286697A1 (en) 2002-10-25 2004-05-13 Norak Biosciences, Inc. Methods of identifying reduced internalization transmembrane receptor agonists
WO2004087054A2 (en) 2003-03-25 2004-10-14 The Regents Of The University Of California Methods for modulating gastric secretion using prokineticin receptor antagonists.
GB0320238D0 (en) 2003-08-29 2003-10-01 Medical Res Council Treatment of disease
CN101326168A (zh) 2005-03-24 2008-12-17 詹森药业有限公司 激肽原1受体拮抗剂
CN102585002A (zh) 2006-06-02 2012-07-18 瑞泽恩制药公司 人il-6受体的高亲和力抗体
NO347649B1 (no) 2006-12-14 2024-02-12 Regeneron Pharma Humant antistoff eller antistoff fragment som spesifikt binder human deltaliknende ligand 4 (hDII4), nukleinsyremolekyl som koder for slike og vektor og vert-vektorsystemer, samt fremgangsmåte for fremstilling, sammensetning og anvendelse.
ITRM20070182A1 (it) * 2007-04-03 2008-10-04 Univ Roma Antagonisti dei recettori delle prochineticine derivati di essi e loro uso
JP5425056B2 (ja) 2007-05-15 2014-02-26 エフ.ホフマン−ラ ロシュ アーゲー Gタンパク質共役受容体(gpcr)に対する抗体
US20100286021A1 (en) 2007-09-25 2010-11-11 Qun-Yong Zhou Methods of Modulating Prokineticin 2 for Treatment of Stress Response and Anxiety-Related Disorders
US8722896B2 (en) * 2008-12-17 2014-05-13 The Regents Of The University Of California Prokineticin receptor antagonists and uses thereof
JO3182B1 (ar) 2009-07-29 2018-03-08 Regeneron Pharma مضادات حيوية بشرية عالية الالفة مع تولد الاوعية البشرية - 2
JO3375B1 (ar) * 2010-11-08 2019-03-13 Regeneron Pharma أجسام مضادة بشرية للجين a1 الشبيه بعامل النخر الورمي (tl1a)
ITMI20111225A1 (it) * 2011-06-30 2012-12-31 Fond I R C C S Istituto Neur Ologico Carlo Uso di antagonisti non peptidici dei recettori per le prokineticine per la terapia di malattie autoimmuni o con componente autoimmune, o di malattie disimmuni o con componente disimmune

Also Published As

Publication number Publication date
JP2016502520A (ja) 2016-01-28
EP2920211A1 (en) 2015-09-23
HK1210182A1 (en) 2016-04-15
SG11201502933UA (en) 2015-05-28
CA2891327A1 (en) 2014-05-22
AU2013345018A1 (en) 2015-05-14
US20180208656A1 (en) 2018-07-26
CN104781280A (zh) 2015-07-15
MX2015005546A (es) 2015-08-05
IL238629A0 (en) 2015-06-30
CO7400866A2 (es) 2015-09-30
US20140134189A1 (en) 2014-05-15
US20150266957A1 (en) 2015-09-24
ZA201502516B (en) 2016-01-27
KR20150084007A (ko) 2015-07-21
WO2014078306A1 (en) 2014-05-22
BR112015010691A2 (pt) 2017-08-22
PH12015500903A1 (en) 2015-07-13
US9951132B2 (en) 2018-04-24
EA201590877A1 (ru) 2015-09-30

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