CL2008000794A1 - Compuestos derivados de biarilo y heteroarilo; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un trastorno de hierro. - Google Patents
Compuestos derivados de biarilo y heteroarilo; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un trastorno de hierro.Info
- Publication number
- CL2008000794A1 CL2008000794A1 CL200800794A CL2008000794A CL2008000794A1 CL 2008000794 A1 CL2008000794 A1 CL 2008000794A1 CL 200800794 A CL200800794 A CL 200800794A CL 2008000794 A CL2008000794 A CL 2008000794A CL 2008000794 A1 CL2008000794 A1 CL 2008000794A1
- Authority
- CL
- Chile
- Prior art keywords
- compounds
- biarilo
- heteroarilo
- treat
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
- C07C323/44—X or Y being nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89566207P | 2007-03-19 | 2007-03-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2008000794A1 true CL2008000794A1 (es) | 2008-05-30 |
Family
ID=39551662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200800794A CL2008000794A1 (es) | 2007-03-19 | 2008-03-19 | Compuestos derivados de biarilo y heteroarilo; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un trastorno de hierro. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20080234384A1 (es) |
| EP (1) | EP2061754A1 (es) |
| JP (1) | JP2010522197A (es) |
| CN (1) | CN101622227A (es) |
| AR (1) | AR065785A1 (es) |
| AU (1) | AU2008228898A1 (es) |
| BR (1) | BRPI0809272A2 (es) |
| CA (1) | CA2678949A1 (es) |
| CL (1) | CL2008000794A1 (es) |
| MX (1) | MX2009010083A (es) |
| RU (1) | RU2009138351A (es) |
| TW (1) | TW200843733A (es) |
| WO (1) | WO2008115999A1 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010005851A1 (en) * | 2008-07-08 | 2010-01-14 | Xenon Pharmaceuticals Inc. | Combination therapy for treating iron disorders |
| TW201035088A (en) | 2009-02-27 | 2010-10-01 | Supergen Inc | Cyclopentathiophene/cyclohexathiophene DNA methyltransferase inhibitors |
| GB0903482D0 (en) * | 2009-02-27 | 2009-04-08 | Ucl Business Plc | New compounds |
| JP2013502399A (ja) | 2009-08-20 | 2013-01-24 | ヴィフォール （インターナショナル） アクチェンゲゼルシャフト | 新規なキノリン系ヘプシジン拮抗薬 |
| AR077958A1 (es) | 2009-08-27 | 2011-10-05 | Vifor Int Ag | Quinoxalinonas antagonistas de la hepcidina |
| AR077999A1 (es) | 2009-09-02 | 2011-10-05 | Vifor Int Ag | Antagonistas de pirimidin y triazin-hepcidina |
| WO2011026959A1 (de) | 2009-09-07 | 2011-03-10 | Vifor (International) Ag | Neue ethandiamin-hepcidin-antagonisten |
| AR078278A1 (es) | 2009-09-09 | 2011-10-26 | Vifor Int Ag | Antagonistas de la tiazol y oxazol hepcidina, composiciones farmaceuticas que los contienen y uso de los mismos para el tratamiento de anemias y enfermedades asociadas a deficiencias de hierro. |
| US20120214803A1 (en) | 2011-02-18 | 2012-08-23 | Vifor (International) Ag | Novel Sulfonaminoquinoline Hepcidin Antagonists |
| CN103073528A (zh) * | 2012-12-21 | 2013-05-01 | 北京万全德众医药生物技术有限公司 | 草酸艾司西酞普兰杂质a的制备方法 |
| CN104370784B (zh) * | 2014-12-11 | 2017-02-22 | 北京彤程创展科技有限公司 | 一种环烷基硫化锌化合物及其制备方法 |
| PE20181496A1 (es) | 2015-10-23 | 2018-09-18 | Vifor Int Ag | Inhibidores de ferroportina novedosos |
| JOP20180036A1 (ar) | 2017-04-18 | 2019-01-30 | Vifor Int Ag | أملاح لمثبطات فروبورتين جديدة |
| US11034669B2 (en) | 2018-11-30 | 2021-06-15 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| TW202102478A (zh) | 2019-04-01 | 2021-01-16 | 瑞士商威佛（國際）股份有限公司 | 新穎的鐵螯合物 |
| WO2024035268A2 (en) * | 2022-08-10 | 2024-02-15 | Qatar Foundation For Education, Science And Community Development | Tau pathway modulators |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2906773A (en) * | 1957-08-01 | 1959-09-29 | Dow Chemical Co | 2, 2'-oxybis (p-phenylenemethylene) bis (2-thiopseudourea) compounds |
| US3247035A (en) * | 1962-09-28 | 1966-04-19 | Standard Oil Co | Ammonium nitrate propellants containing a nitro-aminocarboxy-alkali metal phenolate combustion catalyst |
| FR1541946A (fr) * | 1966-10-27 | 1968-10-11 | Geigy Ag J R | Amines et produits d'entretien des surfaces contenant ces amines |
| NL134627C (es) * | 1966-10-27 | |||
| US3636109A (en) * | 1969-02-05 | 1972-01-18 | Dow Chemical Co | 2 2'-isopropylidenebis((6 - lower alkoxy-m-phenylene)methylene)bis(2 - thiopseudourea) dihydrochlori |
| JPH0791260B2 (ja) * | 1986-12-27 | 1995-10-04 | 第一製薬株式会社 | グアニジン誘導体及びその塩 |
| IL95548A0 (en) * | 1989-09-15 | 1991-06-30 | Fujisawa Pharmaceutical Co | Thiazole derivatives,processes for the preparation thereof and pharmaceutical composition containing the same |
| DE19603425A1 (de) * | 1996-01-31 | 1997-08-07 | Hoechst Ag | Substituierte Diaryldicarbonsäure-diguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE10024319A1 (de) * | 2000-05-17 | 2001-11-22 | Merck Patent Gmbh | Bisacylguanidine |
| US6638967B2 (en) * | 2000-08-08 | 2003-10-28 | Ortho-Mcneil Phamraceutical, Inc. | Thiophene of furan pyrrolidine compounds |
| EP2068855A2 (en) * | 2007-06-05 | 2009-06-17 | Xenon Pharmaceuticals Inc. | Aromatic and heteroaromatic compounds useful in treating iron disorders |
-
2008
- 2008-03-18 AR ARP080101125A patent/AR065785A1/es not_active Application Discontinuation
- 2008-03-19 BR BRPI0809272-9A2A patent/BRPI0809272A2/pt not_active IP Right Cessation
- 2008-03-19 MX MX2009010083A patent/MX2009010083A/es unknown
- 2008-03-19 CN CN200880006800A patent/CN101622227A/zh active Pending
- 2008-03-19 AU AU2008228898A patent/AU2008228898A1/en not_active Abandoned
- 2008-03-19 TW TW097109658A patent/TW200843733A/zh unknown
- 2008-03-19 CA CA002678949A patent/CA2678949A1/en not_active Abandoned
- 2008-03-19 US US12/051,741 patent/US20080234384A1/en not_active Abandoned
- 2008-03-19 CL CL200800794A patent/CL2008000794A1/es unknown
- 2008-03-19 JP JP2009554715A patent/JP2010522197A/ja not_active Withdrawn
- 2008-03-19 EP EP08744072A patent/EP2061754A1/en not_active Withdrawn
- 2008-03-19 WO PCT/US2008/057519 patent/WO2008115999A1/en active Application Filing
- 2008-03-19 RU RU2009138351/04A patent/RU2009138351A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2061754A1 (en) | 2009-05-27 |
| US20080234384A1 (en) | 2008-09-25 |
| WO2008115999A1 (en) | 2008-09-25 |
| AU2008228898A1 (en) | 2008-09-25 |
| BRPI0809272A2 (pt) | 2014-10-14 |
| TW200843733A (en) | 2008-11-16 |
| RU2009138351A (ru) | 2011-04-27 |
| CN101622227A (zh) | 2010-01-06 |
| JP2010522197A (ja) | 2010-07-01 |
| WO2008115999A8 (en) | 2008-12-24 |
| MX2009010083A (es) | 2009-10-12 |
| AR065785A1 (es) | 2009-07-01 |
| CA2678949A1 (en) | 2008-09-25 |
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