CH623044A5 - Process for the preparation of novel anilino-2-oxazolines - Google Patents

Process for the preparation of novel anilino-2-oxazolines Download PDF

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Publication number
CH623044A5
CH623044A5 CH1516475A CH1516475A CH623044A5 CH 623044 A5 CH623044 A5 CH 623044A5 CH 1516475 A CH1516475 A CH 1516475A CH 1516475 A CH1516475 A CH 1516475A CH 623044 A5 CH623044 A5 CH 623044A5
Authority
CH
Switzerland
Prior art keywords
lower alkyl
formula
hydrogen
group
alkoxy
Prior art date
Application number
CH1516475A
Other languages
German (de)
English (en)
Inventor
Bernard R Neustadt
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Priority to ES442992A priority Critical patent/ES442992A1/es
Priority to US05/668,385 priority patent/US4081547A/en
Priority to US05/683,104 priority patent/US4093742A/en
Priority to US05/688,219 priority patent/US4058612A/en
Priority to ES457807A priority patent/ES457807A1/es
Priority to ES457806A priority patent/ES457806A1/es
Priority to US05/872,130 priority patent/US4159335A/en
Publication of CH623044A5 publication Critical patent/CH623044A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH1516475A 1974-12-02 1975-11-21 Process for the preparation of novel anilino-2-oxazolines CH623044A5 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ES442992A ES442992A1 (es) 1974-12-02 1975-11-26 Un procedimiento para preparar 2-anilino-oxazolinas.
US05/668,385 US4081547A (en) 1974-12-02 1976-03-19 Para-polyfluoroisopropyl-anilino-2-oxazoline compounds, pharmaceutical compositions and method of treating hypertension
US05/683,104 US4093742A (en) 1974-12-02 1976-05-04 Anti-hypertensive polyhaloisopropyl-substituted arylureas
US05/688,219 US4058612A (en) 1974-12-02 1976-05-20 6-(Polyhaloisopropyl)quinazoline-2,4-diones
ES457807A ES457807A1 (es) 1974-12-02 1977-04-14 Un procedimiento para la preparacion de fenil ureas.
ES457806A ES457806A1 (es) 1974-12-02 1977-04-14 Un procedimiento para la preparacion de fenil ureas.
US05/872,130 US4159335A (en) 1974-12-02 1978-01-25 Substituted anilino-2-thiazolines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52860374A 1974-12-02 1974-12-02

Publications (1)

Publication Number Publication Date
CH623044A5 true CH623044A5 (en) 1981-05-15

Family

ID=24106378

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1516475A CH623044A5 (en) 1974-12-02 1975-11-21 Process for the preparation of novel anilino-2-oxazolines

Country Status (26)

Country Link
JP (1) JPS5182239A (ja)
AR (2) AR219478A1 (ja)
AT (1) AT357557B (ja)
AU (1) AU501512B2 (ja)
BE (1) BE835899A (ja)
CA (1) CA1063112A (ja)
CH (1) CH623044A5 (ja)
CS (1) CS188259B2 (ja)
DD (1) DD124730A5 (ja)
DE (1) DE2552933A1 (ja)
DK (1) DK535275A (ja)
FI (1) FI753332A (ja)
FR (1) FR2346000A1 (ja)
GB (1) GB1507340A (ja)
HU (1) HU175541B (ja)
IE (1) IE42759B1 (ja)
IL (1) IL48557A (ja)
IT (1) IT1051024B (ja)
LU (1) LU73888A1 (ja)
NL (1) NL7513804A (ja)
NO (1) NO146497C (ja)
PH (1) PH14474A (ja)
PL (2) PL99122B1 (ja)
SE (2) SE7513331L (ja)
SU (2) SU655311A3 (ja)
ZA (1) ZA757457B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52111541A (en) * 1976-02-19 1977-09-19 Scherico Ltd Substituted ureido compound and medical composition containing it as active ingredient
US4107303A (en) 1976-06-24 1978-08-15 E. I. Du Pont De Nemours And Company Antihypertensive hexafluorohydroxyisopropyl benzazepines and benzazocines
DE2839462A1 (de) * 1978-09-11 1980-03-27 Basf Ag Aroylharnstoffe
US6316503B1 (en) * 1999-03-15 2001-11-13 Tularik Inc. LXR modulators
CA2474433A1 (en) 2002-01-30 2003-08-07 Tularik Inc. Arylsulfonamidobenzylic compounds
US7112606B2 (en) 2002-01-30 2006-09-26 Amgen Inc. Heterocyclic arylsulfonamidobenzylic compounds
US20030199578A1 (en) * 2002-04-19 2003-10-23 Turner Sean C. Naphthalene amides as potassium channel openers
CA2965467A1 (en) * 2014-10-24 2016-04-28 Ono Pharmaceutical Co., Ltd. Kcnq2-5 channel activator
JP6197971B1 (ja) * 2016-04-22 2017-09-20 小野薬品工業株式会社 Ｋｃｎｑ２〜５チャネル関連疾患の予防および／または治療剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3453284A (en) * 1966-01-19 1969-07-01 Du Pont Certain 2-(substituted-anilino)-2-oxazolines
FR1543534A (fr) * 1966-09-27 1968-10-25 Bayer Ag Procédé de fabrication de 2-phénylimino-oxazolidines
DE1670752A1 (de) * 1966-09-27 1970-12-23 Bayer Ag Verfahren zur Herstellung von 2-Phenylamino-oxazolinen
FR1543535A (fr) * 1966-09-27 1968-10-25 Bayer Ag Procédé de fabrication de 2-phénylamino-2-oxazolines
DE1670751A1 (de) * 1966-09-27 1970-12-23 Bayer Ag Verfahren zur Herstellung von 2-Phenylamino-2-oxazolinen

Also Published As

Publication number Publication date
FR2346000A1 (fr) 1977-10-28
IL48557A0 (en) 1976-01-30
DD124730A5 (ja) 1977-03-09
PH14474A (en) 1981-08-07
SU685146A3 (ru) 1979-09-05
JPS5182239A (ja) 1976-07-19
IT1051024B (it) 1981-04-21
IL48557A (en) 1979-05-31
AR219478A1 (es) 1980-08-29
CA1063112A (en) 1979-09-25
AU501512B2 (en) 1979-06-21
FI753332A (ja) 1976-06-03
PL102327B1 (pl) 1979-03-31
DE2552933A1 (de) 1976-06-10
GB1507340A (en) 1978-04-12
FR2346000B1 (ja) 1978-11-17
SU655311A3 (ru) 1979-03-30
ZA757457B (en) 1976-11-24
AT357557B (de) 1980-07-25
HU175541B (hu) 1980-08-28
LU73888A1 (ja) 1976-09-06
SE7513331L (sv) 1976-06-03
SE8004364L (sv) 1980-06-11
IE42759L (en) 1976-06-02
BE835899A (fr) 1976-05-25
AR218436A1 (es) 1980-06-13
DK535275A (da) 1976-06-03
IE42759B1 (en) 1980-10-08
NO146497C (no) 1982-10-13
NL7513804A (nl) 1976-06-04
PL99122B1 (pl) 1978-06-30
CS188259B2 (en) 1979-02-28
NO753984L (ja) 1976-06-03
NO146497B (no) 1982-07-05
ATA898575A (de) 1979-12-15
AU8698975A (en) 1977-06-02

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PL Patent ceased