CH559192A5 - 1-substd-1,4-benzodiazepin-2-ones - with anticonvulsant muscle relaxant, sedative and anxiolytic activity - Google Patents
1-substd-1,4-benzodiazepin-2-ones - with anticonvulsant muscle relaxant, sedative and anxiolytic activityInfo
- Publication number
- CH559192A5 CH559192A5 CH574673A CH574673A CH559192A5 CH 559192 A5 CH559192 A5 CH 559192A5 CH 574673 A CH574673 A CH 574673A CH 574673 A CH574673 A CH 574673A CH 559192 A5 CH559192 A5 CH 559192A5
- Authority
- CH
- Switzerland
- Prior art keywords
- substd
- alkyl
- benzodiazepin
- anticonvulsant
- sedative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Title cpds. of formula (I) (where A is ethylene, propylene, or isopropylene B is O, S or NR3, D is carbalkoxy, CN, CONH2, CONH-alkyl, or CON(alkyl)2, R1 is halogen, NO2, CF3, 2-5C alkyl or alkanoyl, R2 is phenyl, o-halophenyl, o,o'-dihalophenyl or 2-pyridyl, R3 is H or alkyl, and n is 1 or 2) and their 4-oxides, and basic salts are prepd. e.g. by reacting a corresp. 1-H substd. cpd. or a 4-oxide thereof with a cpd. X-A-B'-CnH2n-D (where B' is O, S or NR'3 in which R'3 is alkyl or a protecting group) any protecting group R'3 being removed after the reaction.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH574673A CH559192A5 (en) | 1970-10-07 | 1970-10-07 | 1-substd-1,4-benzodiazepin-2-ones - with anticonvulsant muscle relaxant, sedative and anxiolytic activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH574673A CH559192A5 (en) | 1970-10-07 | 1970-10-07 | 1-substd-1,4-benzodiazepin-2-ones - with anticonvulsant muscle relaxant, sedative and anxiolytic activity |
Publications (1)
Publication Number | Publication Date |
---|---|
CH559192A5 true CH559192A5 (en) | 1975-02-28 |
Family
ID=4298645
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH574673A CH559192A5 (en) | 1970-10-07 | 1970-10-07 | 1-substd-1,4-benzodiazepin-2-ones - with anticonvulsant muscle relaxant, sedative and anxiolytic activity |
Country Status (1)
Country | Link |
---|---|
CH (1) | CH559192A5 (en) |
-
1970
- 1970-10-07 CH CH574673A patent/CH559192A5/en not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |