CH529137A - Procédé de préparation de tétrahydroisoquinoléins-carboxamides - Google Patents

Procédé de préparation de tétrahydroisoquinoléins-carboxamides

Info

Publication number
CH529137A
CH529137A CH1269271A CH1269271A CH529137A CH 529137 A CH529137 A CH 529137A CH 1269271 A CH1269271 A CH 1269271A CH 1269271 A CH1269271 A CH 1269271A CH 529137 A CH529137 A CH 529137A
Authority
CH
Switzerland
Prior art keywords
tetrahydroisoquinolins
carboxamides
preparing
preparing tetrahydroisoquinolins
Prior art date
Application number
CH1269271A
Other languages
English (en)
Inventor
Cleveland Helsley Grover
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of CH529137A publication Critical patent/CH529137A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CH1269271A 1970-08-31 1971-08-30 Procédé de préparation de tétrahydroisoquinoléins-carboxamides CH529137A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6859170A 1970-08-31 1970-08-31

Publications (1)

Publication Number Publication Date
CH529137A true CH529137A (fr) 1972-10-15

Family

ID=22083517

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1269271A CH529137A (fr) 1970-08-31 1971-08-30 Procédé de préparation de tétrahydroisoquinoléins-carboxamides

Country Status (10)

Country Link
US (1) US3745162A (fr)
JP (1) JPS4843509B2 (fr)
AU (1) AU448869B2 (fr)
CA (1) CA934378A (fr)
CH (1) CH529137A (fr)
DE (1) DE2143589A1 (fr)
ES (1) ES394541A1 (fr)
FR (1) FR2103641B1 (fr)
GB (1) GB1331710A (fr)
ZA (1) ZA715769B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947456A (en) * 1970-01-06 1976-03-30 Hoffman-La Roche Inc. Substituted 4-phenyl isoquinolines
US3872125A (en) * 1973-03-03 1975-03-18 Sandoz Ag 3-substituted-4-aryl isoquinolines
US3910915A (en) * 1973-07-23 1975-10-07 Searle & Co 1-Aryl-2-{8 (substituted amino)alkanoyl{9 -1,2,3,4-tetrahydroisoquinolines
US3870722A (en) * 1973-11-02 1975-03-11 Sandoz Ag 2-Methyl-3-substituted-4-aryl isoquinolines
GB1463667A (en) * 1973-12-17 1977-02-02 Wyeth John & Brother Ltd Process for preparing thioamides
US4092418A (en) * 1974-03-05 1978-05-30 John Wyeth & Brother Limited Certain 1-carbothioamides of 1,5-naphthyridine derivatives
US4092320A (en) * 1974-03-05 1978-05-30 John Wyeth & Brother Limited Certain 1-(N-acyl)-carbothioamides of 1,5-naphthyridine derivatives
US4410699A (en) * 1981-08-07 1983-10-18 Hoechst-Roussel Pharmaceuticals Inc. Substituted 1,2,3,4-tetrahydro-4-isoquinolinols
SG171914A1 (en) 2008-12-02 2011-07-28 Chiralgen Ltd Method for the synthesis of phosphorus atom modified nucleic acids
AU2010270714B2 (en) 2009-07-06 2015-08-13 Wave Life Sciences Ltd. Novel nucleic acid prodrugs and methods use thereof
US10428019B2 (en) * 2010-09-24 2019-10-01 Wave Life Sciences Ltd. Chiral auxiliaries
DK2734208T3 (en) 2011-07-19 2017-06-19 Wave Life Sciences Ltd PROCEDURES FOR SYNTHESIS OF FUNCTIONALIZED NUCLEIC ACIDS
JP6246121B2 (ja) 2012-07-13 2017-12-13 株式会社新日本科学 キラル核酸アジュバント
SG11201500232UA (en) 2012-07-13 2015-04-29 Wave Life Sciences Pte Ltd Chiral control
US9598458B2 (en) 2012-07-13 2017-03-21 Wave Life Sciences Japan, Inc. Asymmetric auxiliary group
JPWO2015108047A1 (ja) 2014-01-15 2017-03-23 株式会社新日本科学 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤
JPWO2015108048A1 (ja) 2014-01-15 2017-03-23 株式会社新日本科学 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤
EP3095460A4 (fr) 2014-01-15 2017-08-23 Shin Nippon Biomedical Laboratories, Ltd. Adjuvant d'acide nucléique chiral ayant une activité anti-allergique, et agent anti-allergique
US10160969B2 (en) 2014-01-16 2018-12-25 Wave Life Sciences Ltd. Chiral design

Also Published As

Publication number Publication date
JPS4843509B2 (fr) 1973-12-19
AU3271271A (en) 1973-03-01
JPS475678A (fr) 1972-03-25
FR2103641A1 (fr) 1972-04-14
FR2103641B1 (fr) 1974-10-18
ZA715769B (en) 1972-04-26
CA934378A (en) 1973-09-25
ES394541A1 (es) 1974-10-16
GB1331710A (en) 1973-09-26
AU448869B2 (en) 1974-05-30
US3745162A (en) 1973-07-10
DE2143589A1 (de) 1972-03-09

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Legal Events

Date Code Title Description
PL Patent ceased