CA934378A - 1,2,3,4-tetrahydroisoquinoline-2-(thio)-carboxamides - Google Patents
1,2,3,4-tetrahydroisoquinoline-2-(thio)-carboxamidesInfo
- Publication number
- CA934378A CA934378A CA121716A CA121716A CA934378A CA 934378 A CA934378 A CA 934378A CA 121716 A CA121716 A CA 121716A CA 121716 A CA121716 A CA 121716A CA 934378 A CA934378 A CA 934378A
- Authority
- CA
- Canada
- Prior art keywords
- tetrahydroisoquinoline
- carboxamides
- thio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6859170A | 1970-08-31 | 1970-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA934378A true CA934378A (en) | 1973-09-25 |
Family
ID=22083517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA121716A Expired CA934378A (en) | 1970-08-31 | 1971-08-30 | 1,2,3,4-tetrahydroisoquinoline-2-(thio)-carboxamides |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3745162A (fr) |
| JP (1) | JPS4843509B2 (fr) |
| AU (1) | AU448869B2 (fr) |
| CA (1) | CA934378A (fr) |
| CH (1) | CH529137A (fr) |
| DE (1) | DE2143589A1 (fr) |
| ES (1) | ES394541A1 (fr) |
| FR (1) | FR2103641B1 (fr) |
| GB (1) | GB1331710A (fr) |
| ZA (1) | ZA715769B (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3947456A (en) * | 1970-01-06 | 1976-03-30 | Hoffman-La Roche Inc. | Substituted 4-phenyl isoquinolines |
| US3872125A (en) * | 1973-03-03 | 1975-03-18 | Sandoz Ag | 3-substituted-4-aryl isoquinolines |
| US3910915A (en) * | 1973-07-23 | 1975-10-07 | Searle & Co | 1-Aryl-2-{8 (substituted amino)alkanoyl{9 -1,2,3,4-tetrahydroisoquinolines |
| US3870722A (en) * | 1973-11-02 | 1975-03-11 | Sandoz Ag | 2-Methyl-3-substituted-4-aryl isoquinolines |
| GB1463667A (en) * | 1973-12-17 | 1977-02-02 | Wyeth John & Brother Ltd | Process for preparing thioamides |
| US4092418A (en) * | 1974-03-05 | 1978-05-30 | John Wyeth & Brother Limited | Certain 1-carbothioamides of 1,5-naphthyridine derivatives |
| US4092320A (en) * | 1974-03-05 | 1978-05-30 | John Wyeth & Brother Limited | Certain 1-(N-acyl)-carbothioamides of 1,5-naphthyridine derivatives |
| US4410699A (en) * | 1981-08-07 | 1983-10-18 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 1,2,3,4-tetrahydro-4-isoquinolinols |
| ES2616051T3 (es) | 2008-12-02 | 2017-06-09 | Wave Life Sciences Japan, Inc. | Método para la síntesis de ácidos nucleicos modificados en el átomo de fósforo |
| JP5998326B2 (ja) | 2009-07-06 | 2016-09-28 | ウェイブ ライフ サイエンス リミテッドＷａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｌｔｄ． | 新規核酸プロドラッグおよびその使用方法 |
| US10428019B2 (en) * | 2010-09-24 | 2019-10-01 | Wave Life Sciences Ltd. | Chiral auxiliaries |
| EP3248982A1 (fr) | 2011-07-19 | 2017-11-29 | Wave Life Sciences Ltd. | Reactifs de type thiosulfonate pour la synthèse d'acides nucléiques fonctionnalisés |
| PL2872147T3 (pl) | 2012-07-13 | 2023-09-25 | Wave Life Sciences Ltd. | Sposób wytwarzania chiralnych oligonukleotydów |
| SG11201500239VA (en) | 2012-07-13 | 2015-03-30 | Wave Life Sciences Japan | Asymmetric auxiliary group |
| KR101835401B1 (ko) | 2012-07-13 | 2018-03-08 | 신 니뽄 바이오메디칼 라보라토리즈, 엘티디. | 키랄 핵산 어쥬번트 |
| US10322173B2 (en) | 2014-01-15 | 2019-06-18 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent |
| WO2015108048A1 (fr) | 2014-01-15 | 2015-07-23 | 株式会社新日本科学 | Adjuvant d'acide nucléique chiral ayant un effet antitumoral et agent antitumoral |
| JPWO2015108047A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤 |
| SG10201912897UA (en) | 2014-01-16 | 2020-02-27 | Wave Life Sciences Ltd | Chiral design |
-
1970
- 1970-08-31 US US00068591A patent/US3745162A/en not_active Expired - Lifetime
-
1971
- 1971-08-25 GB GB3994471A patent/GB1331710A/en not_active Expired
- 1971-08-25 AU AU32712/71A patent/AU448869B2/en not_active Expired
- 1971-08-26 ES ES394541A patent/ES394541A1/es not_active Expired
- 1971-08-26 JP JP46064812A patent/JPS4843509B2/ja not_active Expired
- 1971-08-30 ZA ZA715769A patent/ZA715769B/xx unknown
- 1971-08-30 CH CH1269271A patent/CH529137A/fr not_active IP Right Cessation
- 1971-08-30 CA CA121716A patent/CA934378A/en not_active Expired
- 1971-08-30 FR FR7131357A patent/FR2103641B1/fr not_active Expired
- 1971-08-31 DE DE19712143589 patent/DE2143589A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU3271271A (en) | 1973-03-01 |
| JPS4843509B2 (fr) | 1973-12-19 |
| ZA715769B (en) | 1972-04-26 |
| DE2143589A1 (de) | 1972-03-09 |
| JPS475678A (fr) | 1972-03-25 |
| CH529137A (fr) | 1972-10-15 |
| FR2103641B1 (fr) | 1974-10-18 |
| GB1331710A (en) | 1973-09-26 |
| FR2103641A1 (fr) | 1972-04-14 |
| AU448869B2 (en) | 1974-05-30 |
| US3745162A (en) | 1973-07-10 |
| ES394541A1 (es) | 1974-10-16 |
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