CA985674A - Cephalosporins useful as intermediates in making cephalexin and improved process for the synthesis of cephalexin - Google Patents

Cephalosporins useful as intermediates in making cephalexin and improved process for the synthesis of cephalexin

Info

Publication number
CA985674A
CA985674A CA076,674A CA76674A CA985674A CA 985674 A CA985674 A CA 985674A CA 76674 A CA76674 A CA 76674A CA 985674 A CA985674 A CA 985674A
Authority
CA
Canada
Prior art keywords
cephalexin
intermediates
synthesis
making
improved process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA076,674A
Other languages
English (en)
Other versions
CA76674S (en
Inventor
William L. Garbrecht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of CA985674A publication Critical patent/CA985674A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
CA076,674A 1969-03-18 1970-03-06 Cephalosporins useful as intermediates in making cephalexin and improved process for the synthesis of cephalexin Expired CA985674A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80831369A 1969-03-18 1969-03-18

Publications (1)

Publication Number Publication Date
CA985674A true CA985674A (en) 1976-03-16

Family

ID=25198435

Family Applications (1)

Application Number Title Priority Date Filing Date
CA076,674A Expired CA985674A (en) 1969-03-18 1970-03-06 Cephalosporins useful as intermediates in making cephalexin and improved process for the synthesis of cephalexin

Country Status (16)

Country Link
US (1) US3632850A (pt)
JP (1) JPS5017991B1 (pt)
AT (1) AT305492B (pt)
BE (1) BE747382A (pt)
BR (1) BR6915024D0 (pt)
CA (1) CA985674A (pt)
CH (1) CH554896A (pt)
CY (1) CY708A (pt)
DK (1) DK143342C (pt)
ES (1) ES377688A1 (pt)
FR (1) FR2039032A5 (pt)
GB (1) GB1270633A (pt)
IE (1) IE34181B1 (pt)
IL (1) IL34050A (pt)
MY (1) MY7300494A (pt)
NL (1) NL7003887A (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852281A (en) * 1970-02-18 1974-12-03 Koninklijke Gist Spiritus Process for the preparation of 7-substituted amino-desacetoxycephalosporanic acid compounds
US3862181A (en) * 1970-10-28 1975-01-21 Squibb & Sons Inc Process for preparing cephalosporins
US4003894A (en) * 1971-08-17 1977-01-18 Gist-Brocades N.V. Preparation of 7-substituted amino-desacetoxycephalosporanic acid compounds
JPS536158B2 (pt) * 1972-03-23 1978-03-04
JPS551272B2 (pt) * 1972-04-14 1980-01-12
JPS4970989A (pt) * 1972-11-15 1974-07-09
JPS50150989U (pt) * 1974-05-31 1975-12-16
US4091214A (en) * 1977-02-25 1978-05-23 Eli Lilly And Company De-esterification process for cephalosporins
US4379739A (en) * 1980-03-31 1983-04-12 Eli Lilly And Company Electrolytic reduction of cephalosporin p-nitrobenzyl esters
CA1164402A (en) * 1980-03-31 1984-03-27 David A. Hall Electrolytic reduction of cephalosporin p-nitrobenzyl esters

Also Published As

Publication number Publication date
IL34050A (en) 1973-02-28
IE34181L (en) 1970-09-18
BR6915024D0 (pt) 1973-05-24
NL7003887A (pt) 1970-09-22
CY708A (en) 1973-10-01
CH554896A (de) 1974-10-15
JPS5017991B1 (pt) 1975-06-25
IL34050A0 (en) 1970-05-21
GB1270633A (en) 1972-04-12
US3632850A (en) 1972-01-04
MY7300494A (en) 1973-12-31
DK143342C (da) 1981-12-07
ES377688A1 (es) 1972-08-01
DE2012955B2 (de) 1976-05-13
IE34181B1 (en) 1975-03-05
BE747382A (fr) 1970-09-14
DE2012955A1 (de) 1970-09-24
AT305492B (de) 1973-02-26
DK143342B (da) 1981-08-10
FR2039032A5 (pt) 1971-01-08

Similar Documents

Publication Publication Date Title
CA1013579A (en) Composite abrasive granules and method of making
CA966123A (en) Process for the production of triazolobenzodiazepines and intermediates
CA1003403A (en) Processes to prepare substituted penicillins and cephalosporins
AU476509B2 (en) Process for the production of polyglycolethere compounds and their use
CA985674A (en) Cephalosporins useful as intermediates in making cephalexin and improved process for the synthesis of cephalexin
CA992899A (en) Method for the production of cephalosporins
CA955269A (en) Process for the preparation of chlorofluoro-derivatives of methane
IL37195A (en) Process for the preparation of cephalexin and hetacephalexin and novel intermediates therefor
CA927193A (en) Method for production of deepfrozen blocks of food and frames for use with the method
AU406156B2 (en) New cephalosporins useful as intermediates in making cephalexin and improved process forthe synthesis of cephalexin
AU1227570A (en) New cephalosporins useful as intermediates in making cephalexin and improved process forthe synthesis of cephalexin
CA986440A (en) Enzymatic production of cephalexin
AU1797070A (en) Process for the production of perborates
CA926391A (en) Process for the preparation of cephalosporins
CA823232A (en) Process for the preparation of 2-cyclopenten-1-ones and novel intermediates therefor
CA813340A (en) Process for the preparation of 2-cyclopenten-1-ones and novel intermediates therefor
AU426561B2 (en) Process forthe preparation of penicillins and cephalosporins
AU6373969A (en) Process forthe preparation of penicillins and cephalosporins
CA823639A (en) Methods and intermediates for the production of gamma-lactones
AU452165B2 (en) Process for the production of and aminobenzylpenicillin
AU488383B2 (en) Improvements in or relating to penicillins and cephalosporins
CA807085A (en) Process for the preparation of phosphors and raw materials therefor
CA839707A (en) Process for the production of adamantaldehydes and intermediates thereof
AU440060B2 (en) Process for purifying and improving the yield of cephaloglycin antibiotic andthe antibiotic thus obtained
AU1720170A (en) Process for the production of and aminobenzylpenicillin