BE747382A - Nouvelles cephalosporines utiles comme intermediaires dans la preparation de la cephalexine, et procede ameliore pour la synthese de la cephalexine - Google Patents

Nouvelles cephalosporines utiles comme intermediaires dans la preparation de la cephalexine, et procede ameliore pour la synthese de la cephalexine

Info

Publication number
BE747382A
BE747382A BE747382DA BE747382A BE 747382 A BE747382 A BE 747382A BE 747382D A BE747382D A BE 747382DA BE 747382 A BE747382 A BE 747382A
Authority
BE
Belgium
Prior art keywords
cephalexin
intermediaries
synthesis
preparation
improved process
Prior art date
Application number
Other languages
English (en)
French (fr)
Inventor
W L Garbrecht
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE747382A publication Critical patent/BE747382A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
BE747382D 1969-03-18 1970-03-13 Nouvelles cephalosporines utiles comme intermediaires dans la preparation de la cephalexine, et procede ameliore pour la synthese de la cephalexine BE747382A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80831369A 1969-03-18 1969-03-18

Publications (1)

Publication Number Publication Date
BE747382A true BE747382A (fr) 1970-09-14

Family

ID=25198435

Family Applications (1)

Application Number Title Priority Date Filing Date
BE747382D BE747382A (fr) 1969-03-18 1970-03-13 Nouvelles cephalosporines utiles comme intermediaires dans la preparation de la cephalexine, et procede ameliore pour la synthese de la cephalexine

Country Status (16)

Country Link
US (1) US3632850A (pt)
JP (1) JPS5017991B1 (pt)
AT (1) AT305492B (pt)
BE (1) BE747382A (pt)
BR (1) BR6915024D0 (pt)
CA (1) CA985674A (pt)
CH (1) CH554896A (pt)
CY (1) CY708A (pt)
DK (1) DK143342C (pt)
ES (1) ES377688A1 (pt)
FR (1) FR2039032A5 (pt)
GB (1) GB1270633A (pt)
IE (1) IE34181B1 (pt)
IL (1) IL34050A (pt)
MY (1) MY7300494A (pt)
NL (1) NL7003887A (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852281A (en) * 1970-02-18 1974-12-03 Koninklijke Gist Spiritus Process for the preparation of 7-substituted amino-desacetoxycephalosporanic acid compounds
US3862181A (en) * 1970-10-28 1975-01-21 Squibb & Sons Inc Process for preparing cephalosporins
US4003894A (en) * 1971-08-17 1977-01-18 Gist-Brocades N.V. Preparation of 7-substituted amino-desacetoxycephalosporanic acid compounds
JPS536158B2 (pt) * 1972-03-23 1978-03-04
JPS551272B2 (pt) * 1972-04-14 1980-01-12
JPS4970989A (pt) * 1972-11-15 1974-07-09
JPS50150989U (pt) * 1974-05-31 1975-12-16
US4091214A (en) * 1977-02-25 1978-05-23 Eli Lilly And Company De-esterification process for cephalosporins
US4379739A (en) * 1980-03-31 1983-04-12 Eli Lilly And Company Electrolytic reduction of cephalosporin p-nitrobenzyl esters
CA1164402A (en) * 1980-03-31 1984-03-27 David A. Hall Electrolytic reduction of cephalosporin p-nitrobenzyl esters

Also Published As

Publication number Publication date
IL34050A (en) 1973-02-28
IE34181L (en) 1970-09-18
BR6915024D0 (pt) 1973-05-24
NL7003887A (pt) 1970-09-22
CY708A (en) 1973-10-01
CH554896A (de) 1974-10-15
CA985674A (en) 1976-03-16
JPS5017991B1 (pt) 1975-06-25
IL34050A0 (en) 1970-05-21
GB1270633A (en) 1972-04-12
US3632850A (en) 1972-01-04
MY7300494A (en) 1973-12-31
DK143342C (da) 1981-12-07
ES377688A1 (es) 1972-08-01
DE2012955B2 (de) 1976-05-13
IE34181B1 (en) 1975-03-05
DE2012955A1 (de) 1970-09-24
AT305492B (de) 1973-02-26
DK143342B (da) 1981-08-10
FR2039032A5 (pt) 1971-01-08

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: ELI LILLY AND CY

Effective date: 19900313