CA958709A - Di- and tri-substituted imidazoles - Google Patents

Di- and tri-substituted imidazoles

Info

Publication number
CA958709A
CA958709A CA106,578A CA106578A CA958709A CA 958709 A CA958709 A CA 958709A CA 106578 A CA106578 A CA 106578A CA 958709 A CA958709 A CA 958709A
Authority
CA
Canada
Prior art keywords
tri
substituted imidazoles
imidazoles
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA106,578A
Other versions
CA106578S (en
Inventor
Frederick C. Novello
John J. Baldwin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of CA958709A publication Critical patent/CA958709A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
CA106,578A 1970-03-16 1971-03-01 Di- and tri-substituted imidazoles Expired CA958709A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2012670A 1970-03-16 1970-03-16

Publications (1)

Publication Number Publication Date
CA958709A true CA958709A (en) 1974-12-03

Family

ID=21796910

Family Applications (1)

Application Number Title Priority Date Filing Date
CA106,578A Expired CA958709A (en) 1970-03-16 1971-03-01 Di- and tri-substituted imidazoles

Country Status (8)

Country Link
US (1) US3691178A (en)
JP (1) JPS5425028B1 (en)
CA (1) CA958709A (en)
CH (1) CH565157A5 (en)
DE (1) DE2112349A1 (en)
FR (1) FR2085714B1 (en)
GB (1) GB1319026A (en)
NL (1) NL7102531A (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7017486A (en) * 1969-12-15 1971-06-17
US3666767A (en) * 1970-01-28 1972-05-30 Warner Lambert Co 2-amino-1-(2-imidazolin-2-yl)-2-imidazolines
US4035390A (en) * 1971-06-19 1977-07-12 Lilly Industries, Ltd. Thiazole derivatives
US3914246A (en) * 1972-05-05 1975-10-21 Merck & Co Inc Tri-substituted imidazoles
US3812136A (en) * 1972-05-05 1974-05-21 Merck & Co Inc Tri-substituted imidazoles
US4058614A (en) * 1973-12-04 1977-11-15 Merck & Co., Inc. Substituted imidazole compounds and therapeutic compositions therewith
US4179512A (en) * 1977-03-01 1979-12-18 Merck & Co., Inc. 4-Substituted-2-arylimidazoles
US4139708A (en) * 1977-05-24 1979-02-13 Sk&F Lab Co. Intermediates and processes useful for preparing medicinal agents imidazolemethylphosphonium salts
US4314844A (en) * 1979-01-11 1982-02-09 Rohm And Haas Company Herbicidal substituted imidazoles
US4281005A (en) * 1979-03-05 1981-07-28 Merck & Co., Inc. Novel 2-pyridylimidazole compounds
US4851424A (en) * 1986-06-06 1989-07-25 Ciba-Geigy Corporation 1-Phenyl-lower alkyl-imidazole 4- or 5-carboxamide compounds which are useful in the treatment of epilepsy
US5872136A (en) * 1996-04-03 1999-02-16 Merck & Co., Inc. Arylheteroaryl inhibitors of farnesyl-protein transferase
WO2009137742A1 (en) * 2008-05-08 2009-11-12 Ampac Fine Chemicals Llc Process for the preparation of cyano-substituted-nitrogen-containing heteroaryl compounds
CN101921234B (en) * 2009-06-12 2012-05-30 中国中化股份有限公司 Method for preparing dexmedetomidine
CN101805294B (en) * 2010-01-12 2015-06-10 北京华禧联合科技发展有限公司 Preparation of dexmedetomidine hydrochloride key intermediate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3147270A (en) * 1961-11-03 1964-09-01 Warner Lambert Pharmaceutical Substituted 2-imidazolines
FR1487345A (en) * 1965-04-16 1967-07-07 Merck & Co Inc New process for the preparation of hydroxylated or hydroxyalkylated alkyl-imidazoles in position 1

Also Published As

Publication number Publication date
US3691178A (en) 1972-09-12
FR2085714A1 (en) 1971-12-31
CH565157A5 (en) 1975-08-15
GB1319026A (en) 1973-05-31
NL7102531A (en) 1971-09-20
DE2112349A1 (en) 1971-10-14
JPS5425028B1 (en) 1979-08-24
FR2085714B1 (en) 1974-08-02

Similar Documents

Publication Publication Date Title
CA988089A (en) Substituted nitroimidazoles useful against tripanosomiasis
CA967962A (en) Substituted benzimidazoles
CA958709A (en) Di- and tri-substituted imidazoles
CA1010890A (en) Fluoroalkylsulfonamidoaryl compounds
CA934629A (en) Combine
AU465029B2 (en) Di-and tri-substituted 1, 2, 4-triazoles
CA1013358A (en) Tri-substituted imidazoles
CA950466A (en) Bis-triazole compounds
CA961487A (en) Benzimidazoles
CA979428A (en) Imidazole compounds
CA838696A (en) Imidazoles
CA840445A (en) Imidazoles
CA952016A (en) Fungicide
CA859762A (en) Imidazole
ZA733052B (en) Tri-substituted imidazoles
CA848979A (en) Imidazole compounds
CA841825A (en) Adder
CA831495A (en) Preservative
CA859152A (en) Organo-vanadium compound
CA837101A (en) Dicyano-monaozo-heterocyclic compound
CA852229A (en) Benzimidazole compounds
CA838340A (en) Thyristor
CA850296A (en) Thyristor
CA856994A (en) Thyristor
CA939362A (en) Nitroimidazole processes