CA947316A - Biologically active substituted amidines - Google Patents

Biologically active substituted amidines

Info

Publication number
CA947316A
CA947316A CA993,746A CA993746A CA947316A CA 947316 A CA947316 A CA 947316A CA 993746 A CA993746 A CA 993746A CA 947316 A CA947316 A CA 947316A
Authority
CA
Canada
Prior art keywords
biologically active
active substituted
substituted amidines
amidines
biologically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA993,746A
Other languages
English (en)
Inventor
Leslie P. Walls
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Application granted granted Critical
Publication of CA947316A publication Critical patent/CA947316A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24Y being a hetero atom
    • C07C279/26X and Y being nitrogen atoms, i.e. biguanides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA993,746A 1966-07-07 1967-06-22 Biologically active substituted amidines Expired CA947316A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB3047966 1966-07-07
GB19028/67A GB1194835A (en) 1966-07-07 1966-07-07 Novel 1-Amidino-3-Phenyl-Urea Derivatives, the preparation thereof and Compositions containing the same
GB5654666 1966-12-16
GB539167 1967-02-03

Publications (1)

Publication Number Publication Date
CA947316A true CA947316A (en) 1974-05-14

Family

ID=27447446

Family Applications (1)

Application Number Title Priority Date Filing Date
CA993,746A Expired CA947316A (en) 1966-07-07 1967-06-22 Biologically active substituted amidines

Country Status (15)

Country Link
US (2) US3539616A (fr)
BE (1) BE700895A (fr)
CA (1) CA947316A (fr)
CH (5) CH500952A (fr)
DE (2) DE1793745A1 (fr)
DK (1) DK125705B (fr)
FR (2) FR1548340A (fr)
GB (1) GB1194835A (fr)
IL (1) IL28189A (fr)
LU (1) LU54053A1 (fr)
MC (1) MC666A1 (fr)
NL (1) NL6709484A (fr)
NO (1) NO126225B (fr)
OA (1) OA02467A (fr)
SE (1) SE330010B (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3761597A (en) * 1967-06-30 1973-09-25 L Walls 1-amidino-3-(substituted-phenyl) urea antimalarial composition and method of use
IL37047A0 (en) * 1970-06-30 1971-08-25 Wellcome Found Substituted amidines,their preparation and pharmaceutical compositions containing them
US4025652A (en) * 1975-03-31 1977-05-24 William H. Rorer, Inc. Amidinoureas
US4488993A (en) * 1972-09-22 1984-12-18 William H. Rorer, Inc. Amidinoureas
US4220658A (en) * 1972-09-22 1980-09-02 William H. Rorer, Inc. Treatment of hypertension with amidinoureas
US4326074A (en) * 1972-09-22 1982-04-20 William H. Rorer, Inc. Amidinoureas
FR2223361B1 (fr) * 1973-03-27 1977-04-29 Philagro Sa
JPS5646157B2 (fr) * 1973-06-05 1981-10-31
ZA743750B (en) * 1973-07-16 1975-06-25 Rorer Inc William H Amindinoureas
US4216230A (en) * 1973-07-16 1980-08-05 William H. Rorer, Inc. Method for alleviating hypertension with amidinoureas
US4216229A (en) * 1973-07-16 1980-08-05 William H. Rorer, Inc. Method for treating gastrointestinal hyperacidity or ulceration with amidinoureas
FR2237625B1 (fr) * 1973-07-16 1978-07-28 Rorer Inc William H
US4283555A (en) * 1973-07-16 1981-08-11 William H. Rorer, Inc. Amidinoureas
US4060635A (en) * 1975-03-31 1977-11-29 William H. Rorer, Inc. Amidinoureas for treating diarrhea
US4150154A (en) * 1975-03-03 1979-04-17 William H. Rorer, Inc. Amidinoureas
US4204000A (en) * 1975-03-31 1980-05-20 William H. Rorer, Inc. Anti-ulcer amidinoureas
US4203920A (en) * 1975-03-31 1980-05-20 William H. Rorer, Inc. Amidinoureas
US4242337A (en) * 1976-03-30 1980-12-30 William H. Rorer, Inc. Method for treatment of diarrheal disease conditions or symptons in mammals
US4242339A (en) * 1976-03-30 1980-12-30 William H. Rorer, Inc. Method for treatment of gastrointestinal spasmodic disease conditions or symptoms in mammals
US4058557A (en) * 1976-03-30 1977-11-15 William H. Rorer, Inc. Amidinoureas
US4353842A (en) * 1978-09-14 1982-10-12 William H. Rorer, Inc. Amidinoureas
US4440949A (en) * 1979-01-08 1984-04-03 William H. Rorer, Inc. Amidinoureas
US4340609A (en) * 1980-01-02 1982-07-20 William H. Rorer, Inc. Amidinourea derivative veterinary compositions for suppression of parasitemia
NL8120313A (nl) * 1981-08-24 1983-07-01 Rorer Int Overseas Heterocyclische amidino-gesubstitueerde ureums en de farmaceutische toepassingen daarvan.
AU575132B2 (en) * 1985-02-15 1988-07-21 Rorer International (Overseas) Inc. Preperation of amidinoureas
EP0648749B1 (fr) * 1993-08-18 1997-12-10 Bayer Ag N-cyanoaryle hétérocycles azotés
US5681794A (en) * 1993-08-18 1997-10-28 Bayer Aktiengesellschaft N-cyanoaryl-nitrogen heterocycles
DE4412079A1 (de) * 1993-08-18 1995-02-23 Bayer Ag N-Cyanoaryl-Stickstoffheterocyclen
DE4335438A1 (de) * 1993-10-18 1995-04-20 Bayer Ag 4-Cyanophenyliminoheterocyclen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3119867A (en) * 1962-01-26 1964-01-28 Clairol Inc Amino, nitro-phenyl-biguanides and amino, nitro-phenyl; guanyl-ureas

Also Published As

Publication number Publication date
FR1548340A (fr) 1968-12-06
DE1793745A1 (de) 1973-05-30
IL28189A (en) 1971-04-28
US3539616A (en) 1970-11-10
BE700895A (fr) 1968-01-04
NL6709484A (fr) 1968-01-08
CH500952A (de) 1970-12-31
OA02467A (fr) 1970-05-05
DE1668843A1 (de) 1972-02-24
CH501599A (de) 1971-01-15
FR7055M (fr) 1969-06-23
GB1194835A (en) 1970-06-10
CH554318A (de) 1974-09-30
US3784582A (en) 1974-01-08
SE330010B (fr) 1970-11-02
DK125705B (da) 1973-03-26
CH501597A (de) 1971-01-15
CH501598A (de) 1971-01-15
MC666A1 (fr) 1968-04-01
LU54053A1 (fr) 1968-03-12
NO126225B (fr) 1973-01-08

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