CA3004737A1 - Nutritional compositions containing butyrate and uses thereof - Google Patents

Nutritional compositions containing butyrate and uses thereof Download PDF

Info

Publication number: CA3004737A1
Authority: CA; Canada
Prior art keywords: nutritional composition; butyrate; protein; dietary; nutritional
Prior art date: 2015-11-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA3004737A

Other languages

English (en)

French (fr)

Inventor

Juan M. Gonzalez

Teartse Tim Lambers

Eric A.F. Van Tol

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

MJN US Holdings LLC

Original Assignee

MJN US Holdings LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-11-09

Filing date

2016-10-19

Publication date

2017-05-18

2015-11-09 Priority claimed from US14/936,014 external-priority patent/US20170127693A1/en

2015-12-04 Priority claimed from US14/959,107 external-priority patent/US10034937B2/en

2016-02-01 Priority claimed from US15/011,797 external-priority patent/US20170215464A1/en

2016-10-19 Application filed by MJN US Holdings LLC filed Critical MJN US Holdings LLC

2017-05-18 Publication of CA3004737A1 publication Critical patent/CA3004737A1/en

Status Abandoned legal-status Critical Current

Links

239000000203 mixture Substances 0.000 title claims abstract description 186
235000016709 nutrition Nutrition 0.000 title claims abstract description 161
FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Natural products CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 title claims abstract description 113
FERIUCNNQQJTOY-UHFFFAOYSA-M Butyrate Chemical compound CCCC([O-])=O FERIUCNNQQJTOY-UHFFFAOYSA-M 0.000 title claims abstract description 75
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102000011632 Caseins Human genes 0.000 claims description 30
BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims description 28
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MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims description 19
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DLRVVLDZNNYCBX-UHFFFAOYSA-N Polydextrose Polymers OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(O)O1 DLRVVLDZNNYCBX-UHFFFAOYSA-N 0.000 claims description 14
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JXPHLUCMHXXHEJ-UHFFFAOYSA-N 2-(aminomethyl)-4-bromoaniline Chemical compound NCC1=CC(Br)=CC=C1N JXPHLUCMHXXHEJ-UHFFFAOYSA-N 0.000 claims description 3
FYPVXEILSNEKOO-UHFFFAOYSA-L calcium;butanoate Chemical compound [Ca+2].CCCC([O-])=O.CCCC([O-])=O FYPVXEILSNEKOO-UHFFFAOYSA-L 0.000 claims description 3
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235000019171 pyridoxine hydrochloride Nutrition 0.000 description 1
239000011764 pyridoxine hydrochloride Substances 0.000 description 1
229960004172 pyridoxine hydrochloride Drugs 0.000 description 1
MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
239000002994 raw material Substances 0.000 description 1
230000009467 reduction Effects 0.000 description 1
230000002207 retinal effect Effects 0.000 description 1
NCYCYZXNIZJOKI-OVSJKPMPSA-N retinal group Chemical group C\C(=C/C=O)\C=C\C=C(\C=C\C1=C(CCCC1(C)C)C)/C NCYCYZXNIZJOKI-OVSJKPMPSA-N 0.000 description 1
229930002330 retinoic acid Natural products 0.000 description 1
229960000342 retinol acetate Drugs 0.000 description 1
235000019173 retinyl acetate Nutrition 0.000 description 1
239000011770 retinyl acetate Substances 0.000 description 1
125000000946 retinyl group Chemical group [H]C([*])([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C1=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
229940108325 retinyl palmitate Drugs 0.000 description 1
235000019172 retinyl palmitate Nutrition 0.000 description 1
239000011769 retinyl palmitate Substances 0.000 description 1
235000009566 rice Nutrition 0.000 description 1
229940100486 rice starch Drugs 0.000 description 1
239000003813 safflower oil Substances 0.000 description 1
235000005713 safflower oil Nutrition 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical group O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
210000002966 serum Anatomy 0.000 description 1
238000001542 size-exclusion chromatography Methods 0.000 description 1
235000020183 skimmed milk Nutrition 0.000 description 1
210000000813 small intestine Anatomy 0.000 description 1
WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
239000004299 sodium benzoate Substances 0.000 description 1
235000010234 sodium benzoate Nutrition 0.000 description 1
229960003885 sodium benzoate Drugs 0.000 description 1
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
239000001509 sodium citrate Substances 0.000 description 1
NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
235000011083 sodium citrates Nutrition 0.000 description 1
APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical compound [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 description 1
239000011684 sodium molybdate Substances 0.000 description 1
235000015393 sodium molybdate Nutrition 0.000 description 1
TVXXNOYZHKPKGW-UHFFFAOYSA-N sodium molybdate (anhydrous) Chemical compound [Na+].[Na+].[O-][Mo]([O-])(=O)=O TVXXNOYZHKPKGW-UHFFFAOYSA-N 0.000 description 1
239000011655 sodium selenate Substances 0.000 description 1
235000018716 sodium selenate Nutrition 0.000 description 1
229960001881 sodium selenate Drugs 0.000 description 1
239000011781 sodium selenite Substances 0.000 description 1
235000015921 sodium selenite Nutrition 0.000 description 1
229960001471 sodium selenite Drugs 0.000 description 1
LROWVYNUWKVTCU-STWYSWDKSA-M sodium sorbate Chemical compound [Na+].C\C=C\C=C\C([O-])=O LROWVYNUWKVTCU-STWYSWDKSA-M 0.000 description 1
235000019250 sodium sorbate Nutrition 0.000 description 1
239000002904 solvent Substances 0.000 description 1
239000003549 soybean oil Substances 0.000 description 1
235000012424 soybean oil Nutrition 0.000 description 1
235000019710 soybean protein Nutrition 0.000 description 1
210000002784 stomach Anatomy 0.000 description 1
235000000346 sugar Nutrition 0.000 description 1
239000011593 sulfur Substances 0.000 description 1
229910052717 sulfur Inorganic materials 0.000 description 1
239000013589 supplement Substances 0.000 description 1
239000003765 sweetening agent Substances 0.000 description 1
239000003826 tablet Substances 0.000 description 1
229960003495 thiamine Drugs 0.000 description 1
UIERGBJEBXXIGO-UHFFFAOYSA-N thiamine mononitrate Chemical compound [O-][N+]([O-])=O.CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N UIERGBJEBXXIGO-UHFFFAOYSA-N 0.000 description 1
AYEKOFBPNLCAJY-UHFFFAOYSA-O thiamine pyrophosphate Chemical compound CC1=C(CCOP(O)(=O)OP(O)(O)=O)SC=[N+]1CC1=CN=C(C)N=C1N AYEKOFBPNLCAJY-UHFFFAOYSA-O 0.000 description 1
235000008170 thiamine pyrophosphate Nutrition 0.000 description 1
YXVCLPJQTZXJLH-UHFFFAOYSA-N thiamine(1+) diphosphate chloride Chemical compound [Cl-].CC1=C(CCOP(O)(=O)OP(O)(O)=O)SC=[N+]1CC1=CN=C(C)N=C1N YXVCLPJQTZXJLH-UHFFFAOYSA-N 0.000 description 1
IWLROWZYZPNOFC-UHFFFAOYSA-N thiamine(1+) triphosphate(1-) Chemical compound CC1=C(CCOP(O)(=O)OP(O)(=O)OP(O)([O-])=O)SC=[N+]1CC1=CN=C(C)N=C1N IWLROWZYZPNOFC-UHFFFAOYSA-N 0.000 description 1
238000004448 titration Methods 0.000 description 1
229950009883 tocopheryl nicotinate Drugs 0.000 description 1
235000015149 toffees Nutrition 0.000 description 1
239000011573 trace mineral Substances 0.000 description 1
235000013619 trace mineral Nutrition 0.000 description 1
229960001727 tretinoin Drugs 0.000 description 1
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
238000001665 trituration Methods 0.000 description 1
235000015112 vegetable and seed oil Nutrition 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
235000013311 vegetables Nutrition 0.000 description 1
NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
235000019156 vitamin B Nutrition 0.000 description 1
239000011720 vitamin B Substances 0.000 description 1
235000010374 vitamin B1 Nutrition 0.000 description 1
239000011691 vitamin B1 Substances 0.000 description 1
235000019164 vitamin B2 Nutrition 0.000 description 1
239000011716 vitamin B2 Substances 0.000 description 1
235000019160 vitamin B3 Nutrition 0.000 description 1
239000011708 vitamin B3 Substances 0.000 description 1
235000001892 vitamin D2 Nutrition 0.000 description 1
239000011653 vitamin D2 Substances 0.000 description 1
MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 1
235000019143 vitamin K2 Nutrition 0.000 description 1
239000011728 vitamin K2 Substances 0.000 description 1
229940041603 vitamin k 3 Drugs 0.000 description 1
239000010497 wheat germ oil Substances 0.000 description 1
235000020255 yak milk Nutrition 0.000 description 1
235000013618 yogurt Nutrition 0.000 description 1
239000011787 zinc oxide Substances 0.000 description 1
235000021241 α-lactalbumin Nutrition 0.000 description 1
IELOKBJPULMYRW-UHFFFAOYSA-N α-tocopherol succinate Chemical compound OC(=O)CCC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C IELOKBJPULMYRW-UHFFFAOYSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nutrition Science (AREA)
Polymers & Plastics (AREA)
Food Science & Technology (AREA)
Mycology (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Pulmonology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Molecular Biology (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Dairy Products (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

CA3004737A 2015-11-09 2016-10-19 Nutritional compositions containing butyrate and uses thereof Abandoned CA3004737A1 (en)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
US14/936,014		2015-11-09
US14/936,014 US20170127693A1 (en)	2015-11-09	2015-11-09	Nutritional compositions containing butyrate and uses thereof
US14/959,107		2015-12-04
US14/959,107 US10034937B2 (en)	2015-12-04	2015-12-04	Synergistic nutritional compositions and uses thereof
US15/011,797 US20170215464A1 (en)	2016-02-01	2016-02-01	Nutritional compositions containing dietary butyrate and uses thereof
US15/011,797		2016-02-01
PCT/US2016/057641 WO2017083067A1 (en)	2015-11-09	2016-10-19	Nutritional compositions containing butyrate and uses thereof

Publications (1)

Publication Number	Publication Date
CA3004737A1 true CA3004737A1 (en)	2017-05-18

Family

ID=57227128

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
CA3004737A Abandoned CA3004737A1 (en)	2015-11-09	2016-10-19	Nutritional compositions containing butyrate and uses thereof
CA3004740A Abandoned CA3004740A1 (en)	2015-11-09	2016-10-19	Nutritional compositions comprising a casein hydrolysate, as well as dietary butyrate and/or a compound for stimulating formation of endogenous butyrate
CA3004722A Abandoned CA3004722A1 (en)	2015-11-09	2016-10-19	Nutritional compositions comprising lactobacillus rhamnosus gg, as well as dietary butyrate and/or a compound for stimulating formation of endogenous butyrate

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
CA3004740A Abandoned CA3004740A1 (en)	2015-11-09	2016-10-19	Nutritional compositions comprising a casein hydrolysate, as well as dietary butyrate and/or a compound for stimulating formation of endogenous butyrate
CA3004722A Abandoned CA3004722A1 (en)	2015-11-09	2016-10-19	Nutritional compositions comprising lactobacillus rhamnosus gg, as well as dietary butyrate and/or a compound for stimulating formation of endogenous butyrate

Country Status (12)

Country	Link
EP (3)	EP3373747A1 (zh)
JP (3)	JP2018537441A (zh)
CN (3)	CN108347986A (zh)
AU (4)	AU2016351456B2 (zh)
BR (3)	BR112018008833A8 (zh)
CA (3)	CA3004737A1 (zh)
HK (1)	HK1256282A1 (zh)
MX (3)	MX2018005651A (zh)
PH (3)	PH12018500994A1 (zh)
SG (3)	SG11201803123PA (zh)
TW (3)	TW201729693A (zh)
WO (3)	WO2017083067A1 (zh)

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US20140308212A1 (en)	2011-11-07	2014-10-16	University Of Louisville Research Foundation, Inc.	Edible plant-derived microvesicle compositions for diagnosis and treatment of disease
CN111511200B (zh)	2017-11-08	2023-11-07	以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心	用于水产养殖的组合物及方法
US20210085744A1 (en) *	2017-11-22	2021-03-25	University Of Louisville Research Foundation, Inc.	Edible plant-derived nanoparticles for regulation of gut microbiota
IT201800003557A1 (it) *	2018-03-14	2019-09-14	Kolfarma S R L	Preparazione farmaceutica o di integratore alimentare a base di alfa-lattoalbumina
CA3121391A1 (en) *	2018-12-21	2020-06-25	Societe Des Produits Nestle S.A.	Dietary butyrate for treating or preventing an allergic disorder
CA3162600A1 (en) *	2019-12-05	2021-06-10	Societe Des Produits Nestle S.A.	Dietary butyrate
CN116585284B (zh) *	2023-06-13	2024-03-19	常州市武进人民医院(常州市第八人民医院)	一种骨化三醇软胶囊、制备方法及其用途

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US4839281A (en)	1985-04-17	1989-06-13	New England Medical Center Hospitals, Inc.	Lactobacillus strains and methods of selection
CN100496468C (zh) *	2004-03-23	2009-06-10	利统股份有限公司	甲壳素包埋或包胶胶囊
CA2604383C (en) *	2005-04-27	2014-09-09	N.V. Nutricia	Nutrition with lipids and non-digestible saccharides
JP2007131550A (ja) *	2005-11-08	2007-05-31	Snow Brand Milk Prod Co Ltd	免疫機能調節剤
ITRM20080214A1 (it) *	2008-04-21	2009-10-22	Uni Degli Studi Di Napoli Federico Ii	Derivati dell'acido butirrico somministrabili per via orale, formulazioni che li contengono e loro uso clinico.
IT1392214B1 (it) *	2008-11-28	2012-02-22	Sila S R L	Processo per la produzione di un composto dell'acido n-butirrico in forma microincapsulata, destinato ad alimentazione animale od umana
IT1395328B1 (it) *	2009-08-26	2012-09-14	Alpiflor S R L	Composizione di acido butirrico miscelato con probiotici e prebiotici
CN103238730B (zh) *	2012-03-22	2014-09-03	杭州康德权饲料有限公司	一种微囊化包膜丁酸钠的制备方法
WO2013191533A1 (en) *	2012-06-18	2013-12-27	N.V. Nutricia	Metabolic imprinting effects of nutrition with large lipid globules comprising milk fat and vegetable fat
US9352020B2 (en) *	2013-03-15	2016-05-31	Mead Johnson Nutrition Company	Reducing proinflammatory response
US8889633B2 (en) *	2013-03-15	2014-11-18	Mead Johnson Nutrition Company	Nutritional compositions containing a peptide component with anti-inflammatory properties and uses thereof
US10709770B2 (en) *	2013-07-31	2020-07-14	Mead Johnson Nutrition Company	Nutritional compositions containing a prebiotic and lactoferrin and uses thereof
US20150119322A1 (en) *	2013-07-31	2015-04-30	Mead Johnson Nutrition Company	Nutritional compositions containing a prebiotic and lactoferrin and uses thereof
US20150271554A1 (en) *	2014-03-18	2015-09-24	Telefonaktiebolaget L M Ericsson (Publ)	Unified rating system and method for selectively blocking content
US20150305384A1 (en) *	2014-04-25	2015-10-29	Mead Johnson Nutrition Company	Pediatric nutritional composition with human milk oligosaccahrides, prebiotics and probiotics

2016
- 2016-10-19 JP JP2018523446A patent/JP2018537441A/ja active Pending
- 2016-10-19 WO PCT/US2016/057641 patent/WO2017083067A1/en active Application Filing
- 2016-10-19 BR BR112018008833A patent/BR112018008833A8/pt not_active Application Discontinuation
- 2016-10-19 MX MX2018005651A patent/MX2018005651A/es unknown
- 2016-10-19 CA CA3004737A patent/CA3004737A1/en not_active Abandoned
- 2016-10-19 JP JP2018523445A patent/JP2018537084A/ja active Pending
- 2016-10-19 AU AU2016351456A patent/AU2016351456B2/en active Active
- 2016-10-19 SG SG11201803123PA patent/SG11201803123PA/en unknown
- 2016-10-19 CN CN201680065433.2A patent/CN108347986A/zh active Pending
- 2016-10-19 BR BR112018008040A patent/BR112018008040A2/pt not_active Application Discontinuation
- 2016-10-19 SG SG11201803121WA patent/SG11201803121WA/en unknown
- 2016-10-19 AU AU2016351454A patent/AU2016351454A1/en not_active Abandoned
- 2016-10-19 SG SG11201803125XA patent/SG11201803125XA/en unknown
- 2016-10-19 CN CN201680065418.8A patent/CN108347985A/zh active Pending
- 2016-10-19 EP EP16790818.5A patent/EP3373747A1/en active Pending
- 2016-10-19 CA CA3004740A patent/CA3004740A1/en not_active Abandoned
- 2016-10-19 CN CN201680065416.9A patent/CN108347984A/zh active Pending
- 2016-10-19 EP EP16791172.6A patent/EP3373749A1/en not_active Withdrawn
- 2016-10-19 MX MX2018005659A patent/MX2018005659A/es unknown
- 2016-10-19 MX MX2018005663A patent/MX2018005663A/es unknown
- 2016-10-19 WO PCT/US2016/057646 patent/WO2017083069A1/en active Application Filing
- 2016-10-19 WO PCT/US2016/057644 patent/WO2017083068A1/en active Application Filing
- 2016-10-19 CA CA3004722A patent/CA3004722A1/en not_active Abandoned
- 2016-10-19 BR BR112018008726A patent/BR112018008726A2/pt not_active Application Discontinuation
- 2016-10-19 EP EP16790819.3A patent/EP3373748A1/en active Pending
- 2016-10-19 AU AU2016351455A patent/AU2016351455B2/en active Active
- 2016-10-19 JP JP2018523455A patent/JP2018532417A/ja active Pending
- 2016-10-27 TW TW105134844A patent/TW201729693A/zh unknown
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2018
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- 2018-11-30 HK HK18115346.9A patent/HK1256282A1/zh unknown
2020
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Also Published As

Publication number	Publication date
EP3373748A1 (en)	2018-09-19
AU2016351455A1 (en)	2018-05-10
WO2017083067A1 (en)	2017-05-18
BR112018008833A2 (pt)	2018-11-06
SG11201803123PA (en)	2018-05-30
WO2017083069A1 (en)	2017-05-18
WO2017083068A1 (en)	2017-05-18
BR112018008726A2 (pt)	2018-10-30
JP2018537441A (ja)	2018-12-20
AU2016351455B2 (en)	2020-08-20
CA3004740A1 (en)	2017-05-18
AU2016351456A1 (en)	2018-05-10
MX2018005659A (es)	2018-08-01
EP3373749A1 (en)	2018-09-19
CN108347986A (zh)	2018-07-31
BR112018008833A8 (pt)	2019-02-26
AU2016351454A1 (en)	2018-05-10
EP3373747A1 (en)	2018-09-19
CN108347985A (zh)	2018-07-31
PH12018500994A1 (en)	2019-01-28
AU2020257046A1 (en)	2020-11-12
CA3004722A1 (en)	2017-05-18
MX2018005651A (es)	2018-08-01
SG11201803125XA (en)	2018-05-30
TW201729691A (zh)	2017-09-01
BR112018008040A2 (pt)	2018-11-13
PH12018500993A1 (en)	2018-11-12
HK1256282A1 (zh)	2019-09-20
PH12018500992A1 (en)	2018-11-12
CN108347984A (zh)	2018-07-31
TW201729693A (zh)	2017-09-01
JP2018532417A (ja)	2018-11-08
MX2018005663A (es)	2018-08-01
JP2018537084A (ja)	2018-12-20
TW201729692A (zh)	2017-09-01
AU2016351456B2 (en)	2020-09-17
SG11201803121WA (en)	2018-05-30
AU2020257046B2 (en)	2022-08-11

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Date	Code	Title	Description
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2024-03-10	FZDE	Discontinued	Effective date: 20230110

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