CA2709960A1 - Chemically modified factor ix - Google Patents
Chemically modified factor ix Download PDFInfo
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- CA2709960A1 CA2709960A1 CA2709960A CA2709960A CA2709960A1 CA 2709960 A1 CA2709960 A1 CA 2709960A1 CA 2709960 A CA2709960 A CA 2709960A CA 2709960 A CA2709960 A CA 2709960A CA 2709960 A1 CA2709960 A1 CA 2709960A1
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
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- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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EP2353588B1 (en) | 2010-01-21 | 2015-04-15 | Agricultural Technology Research Institute | A sustained release preparation of factor IX |
UY35463A (es) | 2013-03-15 | 2014-10-31 | Biogen Idec Inc | Formulaciones de polipéptido fc-factor ix. |
AR099340A1 (es) * | 2014-02-12 | 2016-07-13 | Novo Nordisk As | Conjugados del factor de coagulación ix |
KR102385372B1 (ko) | 2014-03-24 | 2022-04-11 | 바이오버라티브 테라퓨틱스 인크. | 동결건조된 ix 인자 제형 |
US20220378840A1 (en) * | 2019-11-29 | 2022-12-01 | Rutgers, The State University Of New Jersey | Compositions, kits and methods for storage of blood products and methods of use thereof |
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---|---|---|---|---|
JPS538750B2 (ja) | 1971-08-18 | 1978-03-31 | ||
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US5614500A (en) * | 1983-03-04 | 1997-03-25 | The Scripps Research Institute | Compositions containing highly purified factor IX proteins prepared by immunoaffinity chromatography |
DE3313600A1 (de) | 1983-04-14 | 1984-10-18 | Laevosan-Gesellschaft mbH & Co. KG, Linz | Plasmastreckmittel auf staerkebasis und verfahren zu ihrer herstellung |
DE3919729C3 (de) * | 1989-06-16 | 1997-06-19 | Fresenius Ag | Hydroxyethylstärke als Plasmaexpander, Verfahren zu ihrer Herstellung und Verwendung als kolloidales Plasmaersatzmittel |
FR2702160B1 (fr) | 1993-03-02 | 1995-06-02 | Biovecteurs As | Vecteurs particulaires synthétiques et procédé de préparation. |
DE4310974C2 (de) | 1993-04-03 | 1996-08-01 | Fresenius Ag | Verwendung von Hydroxyethylstärke zur Verbesserung der Mikrozirkulation |
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US5621039A (en) * | 1993-06-08 | 1997-04-15 | Hallahan; Terrence W. | Factor IX- polymeric conjugates |
FR2723849B1 (fr) | 1994-08-31 | 1997-04-11 | Biovector Therapeutics Sa | Procede pour augmenter l'immunogenicite, produit obtenu et composition pharmaceutique |
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WO2005014655A2 (en) * | 2003-08-08 | 2005-02-17 | Fresenius Kabi Deutschland Gmbh | Conjugates of hydroxyalkyl starch and a protein |
US20060040856A1 (en) * | 2003-12-03 | 2006-02-23 | Neose Technologies, Inc. | Glycopegylated factor IX |
AU2004296860B2 (en) * | 2003-12-03 | 2010-04-22 | Novo Nordisk A/S | Glycopegylated factor IX |
ZA200608126B (en) | 2004-03-01 | 2008-02-27 | Braun Melsungen Ag | Hydroxyethyl starch |
EP2336192A1 (en) * | 2004-03-11 | 2011-06-22 | Fresenius Kabi Deutschland GmbH | Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination |
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EP1991257B1 (en) * | 2006-03-07 | 2015-05-06 | Baxter International Inc. | Highly phosphorylated and sulfated recombinant factor ix |
CN101454267B (zh) | 2006-03-29 | 2012-09-26 | 帝斯曼知识产权资产管理有限公司 | 姜黄素的合成 |
EP2084274A2 (en) * | 2006-06-19 | 2009-08-05 | Nautilus Technology LLC | Modified coagulation factor ix polypeptides and use thereof for treatment |
-
2008
- 2008-12-19 NZ NZ603997A patent/NZ603997A/xx not_active IP Right Cessation
- 2008-12-19 US US12/339,619 patent/US20090176708A1/en not_active Abandoned
- 2008-12-19 KR KR1020107014071A patent/KR20100110799A/ko not_active Application Discontinuation
- 2008-12-19 CA CA2709960A patent/CA2709960A1/en not_active Abandoned
- 2008-12-19 AU AU2008342260A patent/AU2008342260B2/en not_active Expired - Fee Related
- 2008-12-19 EP EP12008214A patent/EP2568041A1/en not_active Withdrawn
- 2008-12-19 EP EP12008216A patent/EP2568043A1/en not_active Withdrawn
- 2008-12-19 RU RU2010131189/10A patent/RU2010131189A/ru not_active Application Discontinuation
- 2008-12-19 NZ NZ585835A patent/NZ585835A/en not_active IP Right Cessation
- 2008-12-19 NZ NZ598193A patent/NZ598193A/xx not_active IP Right Cessation
- 2008-12-19 JP JP2010540056A patent/JP2011507919A/ja active Pending
- 2008-12-19 EP EP08868384A patent/EP2247723A1/en not_active Withdrawn
- 2008-12-19 WO PCT/EP2008/010925 patent/WO2009083187A1/en active Application Filing
- 2008-12-19 CN CN2008801232530A patent/CN101952422A/zh active Pending
- 2008-12-19 EP EP12008215A patent/EP2568042A1/en not_active Withdrawn
-
2010
- 2010-05-31 IL IL206095A patent/IL206095A0/en unknown
-
2011
- 2011-12-29 US US13/339,823 patent/US20120177625A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
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IL206095A0 (en) | 2010-11-30 |
US20090176708A1 (en) | 2009-07-09 |
NZ585835A (en) | 2012-07-27 |
US20120177625A1 (en) | 2012-07-12 |
WO2009083187A1 (en) | 2009-07-09 |
JP2011507919A (ja) | 2011-03-10 |
CN101952422A (zh) | 2011-01-19 |
WO2009083187A8 (en) | 2009-09-17 |
EP2568043A1 (en) | 2013-03-13 |
EP2568041A1 (en) | 2013-03-13 |
KR20100110799A (ko) | 2010-10-13 |
EP2568042A1 (en) | 2013-03-13 |
RU2010131189A (ru) | 2012-02-10 |
EP2247723A1 (en) | 2010-11-10 |
AU2008342260B2 (en) | 2013-10-17 |
AU2008342260A1 (en) | 2009-07-09 |
NZ603997A (en) | 2013-02-22 |
NZ598193A (en) | 2012-12-21 |
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