CA2692260A1 - Derives de macrolactone - Google Patents

Derives de macrolactone Download PDF

Info

Publication number
CA2692260A1
CA2692260A1 CA002692260A CA2692260A CA2692260A1 CA 2692260 A1 CA2692260 A1 CA 2692260A1 CA 002692260 A CA002692260 A CA 002692260A CA 2692260 A CA2692260 A CA 2692260A CA 2692260 A1 CA2692260 A1 CA 2692260A1
Authority
CA
Canada
Prior art keywords
alkyl
formula
compound
equal
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002692260A
Other languages
English (en)
Inventor
Holger Hoffmann
Christine Klemke-Jahn
Dietmar Schummer
Herbert Kogler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi-Aventis
Holger Hoffmann
Christine Klemke-Jahn
Dietmar Schummer
Herbert Kogler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis, Holger Hoffmann, Christine Klemke-Jahn, Dietmar Schummer, Herbert Kogler filed Critical Sanofi-Aventis
Publication of CA2692260A1 publication Critical patent/CA2692260A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002692260A 2007-07-04 2008-06-20 Derives de macrolactone Abandoned CA2692260A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07290841 2007-07-04
EP07290841.1 2007-07-04
PCT/EP2008/004971 WO2009003595A2 (fr) 2007-07-04 2008-06-20 Dérivés de macrolactone

Publications (1)

Publication Number Publication Date
CA2692260A1 true CA2692260A1 (fr) 2009-01-08

Family

ID=38508880

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002692260A Abandoned CA2692260A1 (fr) 2007-07-04 2008-06-20 Derives de macrolactone

Country Status (23)

Country Link
US (1) US8268775B2 (fr)
EP (1) EP2173756B1 (fr)
JP (1) JP5539193B2 (fr)
KR (1) KR20100031716A (fr)
CN (1) CN101687884B (fr)
AR (1) AR071538A1 (fr)
AT (1) ATE502039T1 (fr)
AU (1) AU2008271631B2 (fr)
BR (1) BRPI0812827A2 (fr)
CA (1) CA2692260A1 (fr)
CL (1) CL2008001973A1 (fr)
DE (1) DE502008002892D1 (fr)
DK (1) DK2173756T3 (fr)
ES (1) ES2362814T3 (fr)
HK (1) HK1142888A1 (fr)
IL (1) IL202990A (fr)
MX (1) MX2009014204A (fr)
MY (1) MY146954A (fr)
PA (1) PA8787001A1 (fr)
PE (1) PE20090736A1 (fr)
PT (1) PT2173756E (fr)
UY (1) UY31204A1 (fr)
WO (1) WO2009003595A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012512224A (ja) * 2008-12-17 2012-05-31 サノフイ マクロラクトン誘導体、その製造方法、及びがんの処置のためのその使用
US11230553B2 (en) 2016-05-09 2022-01-25 The Research Foundation For The State University Of New York Nannocystin process and products
CN106083997B (zh) * 2016-07-05 2021-03-26 北京大学深圳研究生院 Nannocystin A及其结构类似物的合成
CN109280073A (zh) * 2017-07-19 2019-01-29 南开大学 Nannocystins衍生物及其用途
CN109796468B (zh) * 2019-03-26 2021-08-31 南开大学 大环nannocystin衍生物、及其制备方法和用途
CN114907367B (zh) * 2022-05-14 2024-06-14 福建省微生物研究所 大环内酯类化合物fw-z、其发酵菌株、发酵方法及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003505459A (ja) * 1999-07-22 2003-02-12 シエーリング アクチエンゲゼルシャフト エポチロンｂおよび誘導体製造のための方法、ならびにこの方法のための中間製品
WO2006100330A2 (fr) * 2005-03-23 2006-09-28 Consejo Superior De Investigaciones Cientificas Antibiotiques polyenes, compositions les contenant, procede et micro-organismes pour leur obtention et leurs applications

Also Published As

Publication number Publication date
BRPI0812827A2 (pt) 2014-12-09
AR071538A1 (es) 2010-06-30
AU2008271631B2 (en) 2013-06-06
ATE502039T1 (de) 2011-04-15
EP2173756B1 (fr) 2011-03-16
IL202990A (en) 2013-10-31
ES2362814T3 (es) 2011-07-13
AU2008271631A1 (en) 2009-01-08
CL2008001973A1 (es) 2008-11-03
PA8787001A1 (es) 2009-02-09
WO2009003595A2 (fr) 2009-01-08
EP2173756A2 (fr) 2010-04-14
CN101687884B (zh) 2012-10-31
KR20100031716A (ko) 2010-03-24
UY31204A1 (es) 2009-01-30
JP5539193B2 (ja) 2014-07-02
US8268775B2 (en) 2012-09-18
PT2173756E (pt) 2011-05-23
MX2009014204A (es) 2010-01-28
MY146954A (en) 2012-10-15
HK1142888A1 (en) 2010-12-17
JP2010531823A (ja) 2010-09-30
US20100256049A1 (en) 2010-10-07
DE502008002892D1 (de) 2011-04-28
PE20090736A1 (es) 2009-07-17
WO2009003595A3 (fr) 2009-04-09
DK2173756T3 (da) 2011-07-18
CN101687884A (zh) 2010-03-31

Similar Documents

Publication Publication Date Title
IL98506A (en) Peptides, of antibiotics, processes for their preparation and pharmaceutical preparations containing them
US8268775B2 (en) Macrolactone derivatives
US8476222B2 (en) Isolated peptides from Actinomadura namibiensis
EP2379074B1 (fr) Dérivés de macrolactone, procédé pour leur production et leur utilisation pour le traitement du cancer
IL174524A (en) Bengamide derivatives and their medicinal preparations containing them
US8765799B2 (en) Streptospirole derivatives
US20050171089A1 (en) Bengamide derivatives, process for preparing them, and their use
MXPA06004082A (es) Derivados de 2 - fenilbenzofurano, un procedimiento para su preparacion y su uso.
AU738970B2 (en) Novel antibiotic, feglymycin, processes for its preparation and its use
US20200216496A1 (en) Antibacterial Compounds Produced by the Microorganism Strain Corallococcus Coralloides ST201330 (DSM 24989)
JPH08119983A (ja) 新規化合物ｗｆ１４８６５、その製造方法およびその用途
JPH0525150A (ja) 新規デカレストリクチン類および関連化合物、それらの製造方法およびそれらの使用

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20130605

FZDE Discontinued

Effective date: 20160610