CA2648327A1 - Genie tissulaire a l'aide de cellules souches embryonnaires humaines - Google Patents
Genie tissulaire a l'aide de cellules souches embryonnaires humaines Download PDFInfo
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- CA2648327A1 CA2648327A1 CA002648327A CA2648327A CA2648327A1 CA 2648327 A1 CA2648327 A1 CA 2648327A1 CA 002648327 A CA002648327 A CA 002648327A CA 2648327 A CA2648327 A CA 2648327A CA 2648327 A1 CA2648327 A1 CA 2648327A1
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- embryoid bodies
- embryonic stem
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/76—Agarose, agar-agar
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Vascular Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Urology & Nephrology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78985306P | 2006-04-05 | 2006-04-05 | |
| US78985506P | 2006-04-05 | 2006-04-05 | |
| US78985106P | 2006-04-05 | 2006-04-05 | |
| US60/789,851 | 2006-04-05 | ||
| US60/789,853 | 2006-04-05 | ||
| US60/789,855 | 2006-04-05 | ||
| PCT/US2007/066092 WO2007115337A2 (fr) | 2006-04-05 | 2007-04-05 | Ingéniérie tissulaire utilisant des cellules souches embryonnaires humaines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2648327A1 true CA2648327A1 (fr) | 2007-10-11 |
Family
ID=38564326
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002648327A Abandoned CA2648327A1 (fr) | 2006-04-05 | 2007-04-05 | Genie tissulaire a l'aide de cellules souches embryonnaires humaines |
| CA002648332A Abandoned CA2648332A1 (fr) | 2006-04-05 | 2007-04-05 | Approche basee sur la forme pour ingenierie tissulaire sans echafaudage |
| CA002648648A Abandoned CA2648648A1 (fr) | 2006-04-05 | 2007-04-05 | Cellules derivees du derme pour des applications de genie histologique |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
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| CA002648332A Abandoned CA2648332A1 (fr) | 2006-04-05 | 2007-04-05 | Approche basee sur la forme pour ingenierie tissulaire sans echafaudage |
| CA002648648A Abandoned CA2648648A1 (fr) | 2006-04-05 | 2007-04-05 | Cellules derivees du derme pour des applications de genie histologique |
Country Status (4)
| Country | Link |
|---|---|
| EP (3) | EP2007875A4 (fr) |
| AU (3) | AU2007234366A1 (fr) |
| CA (3) | CA2648327A1 (fr) |
| WO (3) | WO2007136936A2 (fr) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2403357T3 (es) | 2003-12-11 | 2013-05-17 | Isto Technologies Inc. | Sistema de cartílago particulado |
| WO2005081970A2 (fr) | 2004-02-24 | 2005-09-09 | The Curators Of The University Of Missouri | Agregats cellulaires d'auto-assemblage et procedes de fabrication de tissu genetiquement modifies utilisant de tels agregats |
| WO2010022074A1 (fr) * | 2008-08-18 | 2010-02-25 | William Marsh Rice University | Procédé de décellularisation pour cartilage articulaire modifié de tissu sans échafaudage ou pour tissu de cartilage natif |
| US20110212894A1 (en) * | 2004-07-09 | 2011-09-01 | Athanasiou Kyriacos A | Decellularization method for scaffoldless tissue engineered articular cartilage or native cartilage tissue |
| WO2009111390A1 (fr) * | 2008-03-03 | 2009-09-11 | William Marsh Rice University | Procédés de fabrication d'un cartilage amélioré d'ingénierie tissulaire |
| JP5292533B2 (ja) | 2005-08-26 | 2013-09-18 | ジンマー・インコーポレイテッド | インプラントおよび関節疾患の治療、置換および治療方法 |
| US8163549B2 (en) | 2006-12-20 | 2012-04-24 | Zimmer Orthobiologics, Inc. | Method of obtaining viable small tissue particles and use for tissue repair |
| CA2684040C (fr) | 2007-04-12 | 2016-12-06 | Isto Technologies, Inc. | Procede de formation d'un implant a l'aide d'un moule imitant la forme du site tissulaire defectueux et implant forme a partir de celui-ci |
| WO2009154466A1 (fr) * | 2008-06-20 | 2009-12-23 | Universiteit Twente | Modules de tissu auto-assemblables |
| EP2310847B1 (fr) | 2008-06-24 | 2016-05-04 | The Curators Of The University Of Missouri | Corps multicellulaires auto-assemblés et procédés de production d une structure biologique tridimensionnelle utilisant ceux-ci |
| CN105796601A (zh) * | 2009-07-16 | 2016-07-27 | 生物时代股份有限公司 | 用于体外和体内软骨发生的方法和组合物 |
| KR20160125530A (ko) | 2010-10-21 | 2016-10-31 | 오가노보, 인크. | 조직의 제작을 위한 디바이스, 시스템 및 방법 |
| WO2013010045A1 (fr) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Nouveaux procédés et formulations pour thérapie cellulaire orthopédique |
| US9499779B2 (en) | 2012-04-20 | 2016-11-22 | Organovo, Inc. | Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking |
| US20140178343A1 (en) | 2012-12-21 | 2014-06-26 | Jian Q. Yao | Supports and methods for promoting integration of cartilage tissue explants |
| US9442105B2 (en) | 2013-03-15 | 2016-09-13 | Organovo, Inc. | Engineered liver tissues, arrays thereof, and methods of making the same |
| SG11201600770RA (en) | 2013-07-31 | 2016-02-26 | Organovo Inc | Automated devices, systems, and methods for the fabrication of tissue |
| CA2944723C (fr) | 2014-04-04 | 2023-03-14 | Organovo, Inc. | Tissu mammaire tridimensionnel artificiel, tissu adipeux, et modele de maladies tumorales |
| US9670443B2 (en) * | 2014-06-25 | 2017-06-06 | University Of Leeds | Tissue engineered constructs |
| MA40495A (fr) | 2014-10-06 | 2016-04-14 | Organovo Inc | Tissus rénaux produits par génie génétique, réseaux correspondants, et procédés de production |
| MA40598A (fr) | 2014-11-05 | 2017-09-13 | Oreal | Tissus cutanés tridimensionnels manipulés, ensembles correspondants et leurs procédés de production |
| JP7007267B2 (ja) | 2015-11-09 | 2022-01-24 | オルガノボ インコーポレイテッド | 組織製造のための改善された方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997017038A1 (fr) * | 1995-11-09 | 1997-05-15 | University Of Massachusetts | Regeneration de surfaces tissulaires a l'aide de compositions hydrogel-cellules |
| WO2000052145A2 (fr) * | 1999-03-02 | 2000-09-08 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus | Lignees cellulaires embryonnaires ou de type souche produites par transplantation nucleaire d'especes croisees |
| JP2004504834A (ja) * | 2000-08-01 | 2004-02-19 | イスム リサーチ ディベロップメント カンパニー | 胚性細胞の定方向分化 |
| AU2002258477A1 (en) * | 2001-03-08 | 2002-09-24 | Advanced Cell Technology, Inc. | Use of rna interference for the creation of lineage specific es and other undifferentiated cells and production of differentiated cells in vitro by co-culture |
| CA2468335C (fr) * | 2001-12-07 | 2014-07-08 | Geron Corporation | Precurseurs de chondrocytes derives de cellules souches embryonnaires humaines |
| US20020106625A1 (en) * | 2002-02-07 | 2002-08-08 | Hung Clark T. | Bioreactor for generating functional cartilaginous tissue |
| AU2003226201A1 (en) * | 2002-04-02 | 2003-10-20 | William Marsh Rice University | Redifferentiated cells for repairing cartilage defects |
| US20040082063A1 (en) * | 2002-10-18 | 2004-04-29 | Reliance Life Sciences Pvt. Ltd. | Tissue-like organization of cells and macroscopic tissue-like constructs, generated by macromass culture of cells, and the method of macromass culture |
| DE602005026690D1 (de) * | 2004-07-09 | 2011-04-14 | Univ Rice William M | Gerüstlose konstrukte für die erzeugung von gelenkknorpel aus gewebe |
-
2007
- 2007-04-05 CA CA002648327A patent/CA2648327A1/fr not_active Abandoned
- 2007-04-05 EP EP07760205A patent/EP2007875A4/fr not_active Withdrawn
- 2007-04-05 AU AU2007234366A patent/AU2007234366A1/en not_active Abandoned
- 2007-04-05 EP EP07760211A patent/EP2007881A4/fr not_active Withdrawn
- 2007-04-05 CA CA002648332A patent/CA2648332A1/fr not_active Abandoned
- 2007-04-05 WO PCT/US2007/066085 patent/WO2007136936A2/fr active Application Filing
- 2007-04-05 EP EP20070760209 patent/EP2007312A4/fr not_active Withdrawn
- 2007-04-05 WO PCT/US2007/066092 patent/WO2007115337A2/fr active Application Filing
- 2007-04-05 WO PCT/US2007/066089 patent/WO2007115336A2/fr active Application Filing
- 2007-04-05 CA CA002648648A patent/CA2648648A1/fr not_active Abandoned
- 2007-04-05 AU AU2007234365A patent/AU2007234365A1/en not_active Abandoned
- 2007-04-05 AU AU2007254048A patent/AU2007254048A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2648648A1 (fr) | 2007-11-29 |
| CA2648332A1 (fr) | 2007-10-11 |
| EP2007312A4 (fr) | 2012-08-22 |
| WO2007136936A3 (fr) | 2008-10-23 |
| WO2007136936A2 (fr) | 2007-11-29 |
| AU2007234366A1 (en) | 2007-10-11 |
| EP2007881A4 (fr) | 2009-07-08 |
| AU2007254048A1 (en) | 2007-11-29 |
| WO2007115337A2 (fr) | 2007-10-11 |
| WO2007115336A2 (fr) | 2007-10-11 |
| EP2007875A4 (fr) | 2009-12-16 |
| AU2007234365A1 (en) | 2007-10-11 |
| EP2007312A2 (fr) | 2008-12-31 |
| EP2007875A2 (fr) | 2008-12-31 |
| EP2007881A2 (fr) | 2008-12-31 |
| WO2007115337A8 (fr) | 2007-12-13 |
| WO2007115336A3 (fr) | 2008-05-22 |
| WO2007115337A3 (fr) | 2008-07-03 |
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