CA2518049C - Method of producing microbial transglutaminase - Google Patents
Method of producing microbial transglutaminase Download PDFInfo
- Publication number
- CA2518049C CA2518049C CA2518049A CA2518049A CA2518049C CA 2518049 C CA2518049 C CA 2518049C CA 2518049 A CA2518049 A CA 2518049A CA 2518049 A CA2518049 A CA 2518049A CA 2518049 C CA2518049 C CA 2518049C
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- ala
- gly
- mtg
- ser
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
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- Chemical & Material Sciences (AREA)
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MXPA02007154A (es) * | 2000-01-21 | 2004-09-06 | Ajinomoto Kk | Procedimiento para producir l-lisina. |
DK1602722T3 (da) | 2003-03-07 | 2011-05-16 | Ajinomoto Kk | Fremgangsmåde til fremstilling af mikrobiel transglutaminase |
WO2005103278A1 (ja) * | 2004-04-20 | 2005-11-03 | Ajinomoto Co., Inc. | タンパク質の製造法 |
JP4631436B2 (ja) * | 2004-12-22 | 2011-02-16 | 岡山県 | メタロエンドペプチダーゼ |
TW200801198A (en) * | 2005-08-30 | 2008-01-01 | Ajinomoto Kk | Method for measuring protease activity of transglutaminase and transglutaminase composition |
JP4905351B2 (ja) * | 2005-08-30 | 2012-03-28 | 味の素株式会社 | プロテアーゼ活性が低減されているトランスグルタミナーゼ含有物の製造方法 |
WO2008099898A1 (ja) * | 2007-02-15 | 2008-08-21 | Ajinomoto Co., Inc. | ジスルフィド結合導入トランスグルタミナーゼ |
EP2138049B1 (en) | 2007-03-29 | 2014-06-25 | Ajinomoto Co., Inc. | Enzyme preparation for adhesion and method of producing adhesion-molded food product |
WO2009066785A1 (ja) | 2007-11-19 | 2009-05-28 | Ajinomoto Co., Inc. | 繊維加工物及びその製造法 |
WO2009102050A1 (ja) * | 2008-02-15 | 2009-08-20 | Ajinomoto Co., Inc. | 腸管免疫賦活剤 |
EP2302066A4 (en) * | 2008-07-09 | 2012-02-08 | Ajinomoto Kk | METHOD FOR PRODUCING AMINOHYDROXYBENZOIC ACID |
TWI444146B (zh) | 2008-09-25 | 2014-07-11 | Ajinomoto Kk | 黏著成型食品用酵素製劑及黏著成型食品之製造方法 |
EP2404999B1 (en) | 2009-03-06 | 2015-04-29 | Ajinomoto Co., Inc. | Thermotolerant transglutaminase originating in actinomyces |
CN107365388B (zh) | 2011-06-23 | 2021-05-14 | 味之素株式会社 | 多聚体蛋白的制备方法 |
WO2013062029A1 (ja) | 2011-10-25 | 2013-05-02 | 味の素株式会社 | タンパク質の分泌生産法 |
WO2013065772A1 (ja) * | 2011-11-02 | 2013-05-10 | 味の素株式会社 | タンパク質の分泌生産法 |
EP2748340B1 (en) | 2011-11-02 | 2016-06-01 | Ajinomoto Co., Inc. | Method for secretory production of proteins |
JP6183358B2 (ja) | 2012-05-29 | 2017-08-23 | 味の素株式会社 | 3−アセチルアミノ−4−ヒドロキシ安息香酸の製造方法 |
CN107075492B (zh) * | 2014-11-10 | 2021-07-27 | 诺维信公司 | 金属蛋白酶及其用途 |
CN108103041A (zh) * | 2018-02-02 | 2018-06-01 | 泰兴市东圣生物科技有限公司 | 一种热稳定微生物转谷氨酰胺酶及其编码基因 |
CN113528479B (zh) * | 2020-04-13 | 2023-01-24 | 中国科学院微生物研究所 | 一种转谷氨酰胺酶的高效制备方法及其专用工程菌 |
CN113528478B (zh) * | 2020-04-13 | 2023-01-20 | 中国科学院微生物研究所 | 一种高效生产转谷氨酰胺酶的方法及其专用工程菌 |
KR102277403B1 (ko) * | 2021-01-27 | 2021-07-14 | 씨제이제일제당 주식회사 | 신규한 리보뉴클레아제 p 변이체 및 이를 이용한 l-글루탐산 생산 방법 |
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JPH0970291A (ja) | 1995-06-30 | 1997-03-18 | Ajinomoto Co Inc | 人工トランスポゾンを用いた遺伝子増幅方法 |
CN1174889A (zh) * | 1997-06-16 | 1998-03-04 | 中国医学科学院医药生物技术研究所 | 一种链霉菌产生的新型纤溶酶 |
ATE532870T1 (de) * | 1999-09-30 | 2011-11-15 | Ajinomoto Kk | Verfahren zur herstellung von transglutaminase |
DE60234247D1 (de) | 2001-03-30 | 2009-12-17 | Ajinomoto Kk | Verfahren zur sekretion und produktion von protein |
DK1602722T3 (da) * | 2003-03-07 | 2011-05-16 | Ajinomoto Kk | Fremgangsmåde til fremstilling af mikrobiel transglutaminase |
WO2005103278A1 (ja) | 2004-04-20 | 2005-11-03 | Ajinomoto Co., Inc. | タンパク質の製造法 |
-
2004
- 2004-03-05 DK DK04717856.1T patent/DK1602722T3/da active
- 2004-03-05 EP EP04717856A patent/EP1602722B1/en not_active Expired - Lifetime
- 2004-03-05 CN CNB2004800062248A patent/CN100381569C/zh not_active Expired - Fee Related
- 2004-03-05 BR BRPI0407911-6A patent/BRPI0407911A/pt not_active Application Discontinuation
- 2004-03-05 AT AT04717856T patent/ATE496995T1/de not_active IP Right Cessation
- 2004-03-05 WO PCT/JP2004/002923 patent/WO2004078973A1/ja active Application Filing
- 2004-03-05 KR KR1020057016640A patent/KR20050106502A/ko not_active Application Discontinuation
- 2004-03-05 JP JP2005503155A patent/JP4482938B2/ja not_active Expired - Fee Related
- 2004-03-05 DE DE602004031198T patent/DE602004031198D1/de not_active Expired - Lifetime
- 2004-03-05 CA CA2518049A patent/CA2518049C/en not_active Expired - Lifetime
- 2004-03-05 ES ES04717856T patent/ES2356149T3/es not_active Expired - Lifetime
- 2004-03-05 RU RU2005127869/13A patent/RU2316594C2/ru active
-
2005
- 2005-09-06 US US11/218,780 patent/US7704707B2/en active Active
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2010
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Also Published As
Publication number | Publication date |
---|---|
DE602004031198D1 (de) | 2011-03-10 |
KR20050106502A (ko) | 2005-11-09 |
EP1602722A4 (en) | 2006-08-02 |
ES2356149T3 (es) | 2011-04-05 |
US20060019367A1 (en) | 2006-01-26 |
RU2005127869A (ru) | 2006-02-10 |
CA2518049A1 (en) | 2004-09-16 |
RU2316594C2 (ru) | 2008-02-10 |
US8105802B2 (en) | 2012-01-31 |
EP1602722B1 (en) | 2011-01-26 |
JPWO2004078973A1 (ja) | 2006-06-08 |
WO2004078973A1 (ja) | 2004-09-16 |
CN100381569C (zh) | 2008-04-16 |
DK1602722T3 (da) | 2011-05-16 |
EP1602722A1 (en) | 2005-12-07 |
ATE496995T1 (de) | 2011-02-15 |
JP4482938B2 (ja) | 2010-06-16 |
US20100159560A1 (en) | 2010-06-24 |
CN1759180A (zh) | 2006-04-12 |
US7704707B2 (en) | 2010-04-27 |
BRPI0407911A (pt) | 2006-02-14 |
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