CA2432792C - Procedes relatifs a la modulation de la croissance tumorale et de la metastase - Google Patents
Procedes relatifs a la modulation de la croissance tumorale et de la metastase Download PDFInfo
- Publication number
- CA2432792C CA2432792C CA2432792A CA2432792A CA2432792C CA 2432792 C CA2432792 C CA 2432792C CA 2432792 A CA2432792 A CA 2432792A CA 2432792 A CA2432792 A CA 2432792A CA 2432792 C CA2432792 C CA 2432792C
- Authority
- CA
- Canada
- Prior art keywords
- combretastatin
- compound
- tumor
- administration
- agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
L'invention concerne des procédés et des compositions pharmaceutiques pour la modulation de la croissance tumorale ou de la métastase.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25819500P | 2000-12-22 | 2000-12-22 | |
US60/258,195 | 2000-12-22 | ||
PCT/US2001/050261 WO2002056692A1 (fr) | 2000-12-22 | 2001-12-20 | Procedes relatifs a la modulation de la croissance tumorale et de la metastase |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2432792A1 CA2432792A1 (fr) | 2002-07-25 |
CA2432792C true CA2432792C (fr) | 2012-04-03 |
Family
ID=22979500
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2432792A Expired - Fee Related CA2432792C (fr) | 2000-12-22 | 2001-12-20 | Procedes relatifs a la modulation de la croissance tumorale et de la metastase |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1351573A4 (fr) |
JP (2) | JP2004523517A (fr) |
AU (1) | AU2002246827B2 (fr) |
CA (1) | CA2432792C (fr) |
WO (1) | WO2002056692A1 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69931766T2 (de) | 1998-04-03 | 2007-05-31 | Ajinomoto Co., Inc. | Antitumorale mittel |
AU2002216029B2 (en) | 2000-10-27 | 2006-01-05 | Pfizer, Inc. | A combination comprising camptothecin and a stilbene derivative for the treatment of cancer |
WO2002056692A1 (fr) * | 2000-12-22 | 2002-07-25 | Bristol-Myers Squibb Company | Procedes relatifs a la modulation de la croissance tumorale et de la metastase |
US20050209310A1 (en) * | 2000-12-22 | 2005-09-22 | Chaplin David J | Methods for modulating tumor growth and metastasis |
US20020183266A1 (en) * | 2001-03-15 | 2002-12-05 | Aventis Pharma, S.A. | Combination comprising combretastatin and anticancer agents |
JP2006503852A (ja) * | 2002-09-25 | 2006-02-02 | ユニバーシティー オブ ロチェスター | 抗癌薬としてのカスパーゼインヒビター |
WO2004032947A1 (fr) * | 2002-10-09 | 2004-04-22 | Unibioscreen S.A. | Extrait ayant un action antitumoral et antitoxique |
TWI323662B (en) * | 2002-11-15 | 2010-04-21 | Telik Inc | Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy |
US9050378B2 (en) | 2003-12-10 | 2015-06-09 | Board Of Regents, The University Of Texas System | N2S2 chelate-targeting ligand conjugates |
US10925977B2 (en) | 2006-10-05 | 2021-02-23 | Ceil>Point, LLC | Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications |
EP2047858A1 (fr) * | 2007-10-10 | 2009-04-15 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Produits de combinaison pour le traitement contre le cancer |
ES2529434T3 (es) * | 2007-11-21 | 2015-02-20 | Oxigene, Inc. | Método para tratar neoplasias hematopoyéticas |
US20090209496A1 (en) * | 2008-02-15 | 2009-08-20 | David Chaplin | Methods and compositions for enhancing the efficacy of rtk inhibitors |
FR2939665B1 (fr) | 2008-12-12 | 2011-10-07 | Sanofi Aventis | Combinaison antitumorale associant l'ave8062a et le docetaxel |
JP2018523712A (ja) | 2015-08-18 | 2018-08-23 | マテオン セラピューティクス, インク.Mateon Therapeutics, Inc. | 腫瘍に対する免疫調節療法を向上させる為のvdasの使用 |
CN107773556B (zh) * | 2016-08-26 | 2020-08-18 | 广州安好医药科技有限公司 | 一种具有抗肿瘤药物功效的联合用药物 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4996237A (en) | 1987-01-06 | 1991-02-26 | Arizona Board Of Regents | Combretastatin A-4 |
CA1338645C (fr) | 1987-01-06 | 1996-10-15 | George R. Pettit | Isolation, caracterisation structurelle et synthese de nouvelles substances antineoplastiques, appelees "combretastatines" |
US5561122A (en) | 1994-12-22 | 1996-10-01 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Combretastatin A-4 prodrug |
WO1999035150A1 (fr) | 1998-01-09 | 1999-07-15 | Arizona Board Of Regents, A Body Corporate, Acting On Behalf Of Arizona State University | Synthese de promedicaments a base de combrestatine a-4 et de leurs trans-isomeres |
GB9903404D0 (en) * | 1999-02-16 | 1999-04-07 | Angiogene Pharm Ltd | Methods of treatment and compositions useful for the treatment of diseases involving angiogenesis |
US6538038B1 (en) | 1999-02-18 | 2003-03-25 | Oxigene, Inc. | Compositions and methods for use in targeting vascular destruction |
WO2002056692A1 (fr) * | 2000-12-22 | 2002-07-25 | Bristol-Myers Squibb Company | Procedes relatifs a la modulation de la croissance tumorale et de la metastase |
-
2001
- 2001-12-20 WO PCT/US2001/050261 patent/WO2002056692A1/fr active Application Filing
- 2001-12-20 JP JP2002557211A patent/JP2004523517A/ja active Pending
- 2001-12-20 CA CA2432792A patent/CA2432792C/fr not_active Expired - Fee Related
- 2001-12-20 EP EP01994435A patent/EP1351573A4/fr not_active Withdrawn
- 2001-12-20 AU AU2002246827A patent/AU2002246827B2/en not_active Ceased
-
2008
- 2008-12-10 JP JP2008315096A patent/JP2009102350A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2004523517A (ja) | 2004-08-05 |
AU2002246827B2 (en) | 2008-02-21 |
EP1351573A1 (fr) | 2003-10-15 |
CA2432792A1 (fr) | 2002-07-25 |
EP1351573A4 (fr) | 2007-03-28 |
JP2009102350A (ja) | 2009-05-14 |
WO2002056692A1 (fr) | 2002-07-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20171220 |