CA2356446A1 - Pyruvate carboxylase from corynebacterium glutamicum - Google Patents

Pyruvate carboxylase from corynebacterium glutamicum Download PDF

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Publication number
CA2356446A1
CA2356446A1 CA002356446A CA2356446A CA2356446A1 CA 2356446 A1 CA2356446 A1 CA 2356446A1 CA 002356446 A CA002356446 A CA 002356446A CA 2356446 A CA2356446 A CA 2356446A CA 2356446 A1 CA2356446 A1 CA 2356446A1
Authority
CA
Canada
Prior art keywords
pyruvate carboxylase
sequence
amino acid
nucleotide sequence
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002356446A
Other languages
English (en)
French (fr)
Inventor
Anthony J. Sinskey
Philip A. Lessard
Laura B. Willis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2356446A1 publication Critical patent/CA2356446A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
    • C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01001—Pyruvate carboxylase (6.4.1.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002356446A 1998-12-23 1998-12-23 Pyruvate carboxylase from corynebacterium glutamicum Abandoned CA2356446A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/027301 WO2000039305A1 (en) 1998-12-23 1998-12-23 PYRUVATE CARBOXYLASE FROM $i(CORYNEBACTERIUM GLUTAMICUM)

Publications (1)

Publication Number Publication Date
CA2356446A1 true CA2356446A1 (en) 2000-07-06

Family

ID=22268534

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002356446A Abandoned CA2356446A1 (en) 1998-12-23 1998-12-23 Pyruvate carboxylase from corynebacterium glutamicum

Country Status (9)

Country Link
EP (1) EP1147198A1 (pt)
JP (1) JP2003503006A (pt)
KR (1) KR20010112232A (pt)
CN (1) CN1336958A (pt)
AU (1) AU2203399A (pt)
BR (1) BR9816106A (pt)
CA (1) CA2356446A1 (pt)
MX (1) MXPA01006290A (pt)
WO (1) WO2000039305A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999053035A1 (en) 1998-04-13 1999-10-21 The University Of Georgia Research Foundation, Inc. Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
US6965021B2 (en) * 2000-10-13 2005-11-15 Archer-Daniels-Midland Company Feedback-resistant pyruvate carboxylase gene from corynebacterium
DE102006032634A1 (de) 2006-07-13 2008-01-17 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
EP3170889A1 (en) * 2006-09-15 2017-05-24 CJ Cheiljedang Corporation A corynebacteria having enhanced l-lysine productivity and a method of producing l-lysine using the same
KR100830826B1 (ko) 2007-01-24 2008-05-19 씨제이제일제당 (주) 코리네박테리아를 이용하여 글리세롤을 포함한탄소원으로부터 발효산물을 생산하는 방법
KR101126041B1 (ko) 2008-04-10 2012-03-19 씨제이제일제당 (주) 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로형질전환된 미생물 및 이를 이용한 ｌ-라이신 생산방법
US8932861B2 (en) 2008-04-10 2015-01-13 Cj Cheiljedang Corporation Transformation vector comprising transposon, microorganisms transformed with the vector, and method for producing L-lysine using the microorganism
DE102008001874A1 (de) 2008-05-20 2009-11-26 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
DE102008044768A1 (de) 2008-08-28 2010-03-04 Evonik Degussa Gmbh Verfahren zur Herstellung von organisch-chemischen Verbindungen unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
RU2615454C1 (ru) * 2011-12-21 2017-04-04 СиДжей ЧеилДжеданг Корпорейшн Способ получения L-лизина с использованием микроорганизмов, обладающих способностью продуцировать L-лизин
CN103695454A (zh) * 2013-12-18 2014-04-02 山东寿光巨能金玉米开发有限公司 表达l-赖氨酸转运蛋白的重组质粒、工程菌及应用
KR101922113B1 (ko) * 2017-04-25 2018-11-27 한양대학교 산학협력단 패오닥틸럼 트리코누튬 유래 피루브산 전달효소
CN113755492B (zh) * 2020-07-20 2023-05-30 中国科学院天津工业生物技术研究所 丙酮酸羧化酶基因启动子的突变体及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2169170C (en) * 1993-08-24 2007-01-09 Masakazu Sugimoto Mutant phosphoenolpyruvate carboxylase, its gene, and production method of amino acid
ES2238773T3 (es) * 1997-10-04 2005-09-01 Degussa Ag Procedimiento para la produccion microbiana de aminoacidos de las familias del aspartato y/o glutamato, y agentes utilizables en el procedimiento.

Also Published As

Publication number Publication date
JP2003503006A (ja) 2003-01-28
KR20010112232A (ko) 2001-12-20
AU2203399A (en) 2000-07-31
CN1336958A (zh) 2002-02-20
WO2000039305A1 (en) 2000-07-06
EP1147198A1 (en) 2001-10-24
BR9816106A (pt) 2001-09-11
MXPA01006290A (es) 2002-04-17

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