CA2338396A1 - Ameliorations par ultra-sons de l'injection de medicaments - Google Patents

Ameliorations par ultra-sons de l'injection de medicaments Download PDF

Info

Publication number
CA2338396A1
CA2338396A1 CA002338396A CA2338396A CA2338396A1 CA 2338396 A1 CA2338396 A1 CA 2338396A1 CA 002338396 A CA002338396 A CA 002338396A CA 2338396 A CA2338396 A CA 2338396A CA 2338396 A1 CA2338396 A1 CA 2338396A1
Authority
CA
Canada
Prior art keywords
substance
vibrational energy
tissue
target region
catheter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002338396A
Other languages
English (en)
Inventor
Jeff Isner
Meno Nassi
John Mckenzie
Robert Zuk
Alex Brisken
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmasonics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/126,011 external-priority patent/US6464680B1/en
Application filed by Individual filed Critical Individual
Publication of CA2338396A1 publication Critical patent/CA2338396A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne un procédé permettant d'améliorer l'absorption cellulaire d'une substance administrée dans la zone cible du corps d'un patient. Ce procédé consiste à administrer la substance (21) dans une zone cible (22); et diriger l'énergie vibratoire (32) vers la zone cible. L'énergie vibratoire est d'un type approprié et en quantité suffisante pour améliorer l'absorption dans les cellules (24) de la zone cible.
CA002338396A 1998-07-29 1999-07-29 Ameliorations par ultra-sons de l'injection de medicaments Abandoned CA2338396A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/126,011 US6464680B1 (en) 1998-07-29 1998-07-29 Ultrasonic enhancement of drug injection
US09/126,011 1998-07-29
US25529099A 1999-02-22 1999-02-22
US09/255,290 1999-02-22
PCT/US1999/017305 WO2000006032A1 (fr) 1998-07-29 1999-07-29 Ameliorations par ultra-sons de l'injection de medicaments

Publications (1)

Publication Number Publication Date
CA2338396A1 true CA2338396A1 (fr) 2000-02-10

Family

ID=26824191

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002338396A Abandoned CA2338396A1 (fr) 1998-07-29 1999-07-29 Ameliorations par ultra-sons de l'injection de medicaments

Country Status (6)

Country Link
EP (1) EP1107702A4 (fr)
JP (1) JP2002521118A (fr)
AU (1) AU754022B2 (fr)
BR (1) BR9912587A (fr)
CA (1) CA2338396A1 (fr)
WO (1) WO2000006032A1 (fr)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6050943A (en) 1997-10-14 2000-04-18 Guided Therapy Systems, Inc. Imaging, therapy, and temperature monitoring ultrasonic system
WO2000048518A1 (fr) * 1999-02-22 2000-08-24 Pharmasonics, Inc. Methodes et appareil destines a la therapie transcutanee par champs uniforme d'ultrasons
US7914453B2 (en) 2000-12-28 2011-03-29 Ardent Sound, Inc. Visual imaging system for ultrasonic probe
US6623444B2 (en) * 2001-03-21 2003-09-23 Advanced Medical Applications, Inc. Ultrasonic catheter drug delivery method and device
US20030147812A1 (en) * 2001-12-11 2003-08-07 Friedrich Ueberle Device and methods for initiating chemical reactions and for the targeted delivery of drugs or other agents
US7358226B2 (en) * 2003-08-27 2008-04-15 The Regents Of The University Of California Ultrasonic concentration of drug delivery capsules
US9011336B2 (en) 2004-09-16 2015-04-21 Guided Therapy Systems, Llc Method and system for combined energy therapy profile
US7824348B2 (en) 2004-09-16 2010-11-02 Guided Therapy Systems, L.L.C. System and method for variable depth ultrasound treatment
US7393325B2 (en) 2004-09-16 2008-07-01 Guided Therapy Systems, L.L.C. Method and system for ultrasound treatment with a multi-directional transducer
US10864385B2 (en) 2004-09-24 2020-12-15 Guided Therapy Systems, Llc Rejuvenating skin by heating tissue for cosmetic treatment of the face and body
US8444562B2 (en) 2004-10-06 2013-05-21 Guided Therapy Systems, Llc System and method for treating muscle, tendon, ligament and cartilage tissue
US8535228B2 (en) 2004-10-06 2013-09-17 Guided Therapy Systems, Llc Method and system for noninvasive face lifts and deep tissue tightening
US9694212B2 (en) 2004-10-06 2017-07-04 Guided Therapy Systems, Llc Method and system for ultrasound treatment of skin
EP1879502A2 (fr) 2004-10-06 2008-01-23 Guided Therapy Systems, L.L.C. Methode et systeme de chirurgie esthetique non invasif
US8133180B2 (en) 2004-10-06 2012-03-13 Guided Therapy Systems, L.L.C. Method and system for treating cellulite
ES2643864T3 (es) 2004-10-06 2017-11-24 Guided Therapy Systems, L.L.C. Procedimiento y sistema para el tratamiento de tejidos por ultrasonidos
US20060111744A1 (en) 2004-10-13 2006-05-25 Guided Therapy Systems, L.L.C. Method and system for treatment of sweat glands
US7758524B2 (en) 2004-10-06 2010-07-20 Guided Therapy Systems, L.L.C. Method and system for ultra-high frequency ultrasound treatment
US9827449B2 (en) 2004-10-06 2017-11-28 Guided Therapy Systems, L.L.C. Systems for treating skin laxity
US11235179B2 (en) 2004-10-06 2022-02-01 Guided Therapy Systems, Llc Energy based skin gland treatment
US11883688B2 (en) 2004-10-06 2024-01-30 Guided Therapy Systems, Llc Energy based fat reduction
US8690778B2 (en) 2004-10-06 2014-04-08 Guided Therapy Systems, Llc Energy-based tissue tightening
US11207548B2 (en) 2004-10-07 2021-12-28 Guided Therapy Systems, L.L.C. Ultrasound probe for treating skin laxity
US11724133B2 (en) 2004-10-07 2023-08-15 Guided Therapy Systems, Llc Ultrasound probe for treatment of skin
EP1875327A2 (fr) 2005-04-25 2008-01-09 Guided Therapy Systems, L.L.C. Procede et systeme pour ameliorer la securite de peripherique d'ordinateur
US20070232986A1 (en) * 2006-03-31 2007-10-04 Cytodome, Inc. Low-profile implantable ultrasound array and method for enhancing drug delivery to tissue
US9566454B2 (en) 2006-09-18 2017-02-14 Guided Therapy Systems, Llc Method and sysem for non-ablative acne treatment and prevention
JP2010526589A (ja) * 2007-05-07 2010-08-05 ガイデッド セラピー システムズ， エル．エル．シー． 音響エネルギーを使用してメディカントを調節するための方法およびシステム
US20150174388A1 (en) 2007-05-07 2015-06-25 Guided Therapy Systems, Llc Methods and Systems for Ultrasound Assisted Delivery of a Medicant to Tissue
CN104545998B (zh) 2008-06-06 2020-07-14 奥赛拉公司 用于美容处理和成像的***和方法
CA2748362A1 (fr) 2008-12-24 2010-07-01 Michael H. Slayton Procedes et systemes pour reduire les graisses et/ou traiter la cellulite
US8715186B2 (en) 2009-11-24 2014-05-06 Guided Therapy Systems, Llc Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
US9504446B2 (en) 2010-08-02 2016-11-29 Guided Therapy Systems, Llc Systems and methods for coupling an ultrasound source to tissue
WO2012018385A2 (fr) 2010-08-02 2012-02-09 Guided Therapy Systems, Llc Système et méthode de traitement du cartilage
US8857438B2 (en) 2010-11-08 2014-10-14 Ulthera, Inc. Devices and methods for acoustic shielding
KR102068724B1 (ko) 2011-07-10 2020-01-21 가이디드 테라피 시스템스, 엘.엘.씨. 에너지원으로 초음파를 이용한 피부 외양을 개선하는 시스템 및 방법
KR20190080967A (ko) 2011-07-11 2019-07-08 가이디드 테라피 시스템스, 엘.엘.씨. 조직에 초음파원을 연결하는 시스템 및 방법
US9263663B2 (en) 2012-04-13 2016-02-16 Ardent Sound, Inc. Method of making thick film transducer arrays
US9510802B2 (en) 2012-09-21 2016-12-06 Guided Therapy Systems, Llc Reflective ultrasound technology for dermatological treatments
CN204637350U (zh) 2013-03-08 2015-09-16 奥赛拉公司 美学成像与处理***、多焦点处理***和执行美容过程的***
US10561862B2 (en) 2013-03-15 2020-02-18 Guided Therapy Systems, Llc Ultrasound treatment device and methods of use
EP3131630B1 (fr) 2014-04-18 2023-11-29 Ulthera, Inc. Traitement par ultrasons émis par un transducteur à bandes
AU2017208980B2 (en) 2016-01-18 2022-03-31 Ulthera, Inc. Compact ultrasound device having annular ultrasound array peripherally electrically connected to flexible printed circuit board and method of assembly thereof
RU2748788C2 (ru) 2016-08-16 2021-05-31 Ультера, Инк. Системы и способы для косметической ультразвуковой обработки кожи
US11944849B2 (en) 2018-02-20 2024-04-02 Ulthera, Inc. Systems and methods for combined cosmetic treatment of cellulite with ultrasound
WO2021100316A1 (fr) * 2019-11-18 2021-05-27 株式会社カネカ Système de diffusion de solution médicamenteuse et dispositif favorisant la diffusion d'une solution médicamenteuse
CN112023243B (zh) * 2020-09-15 2022-03-25 南京大学 超声循环聚焦发射的透皮给药装置及控制方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5016615A (en) * 1990-02-20 1991-05-21 Riverside Research Institute Local application of medication with ultrasound
US5197946A (en) * 1990-06-27 1993-03-30 Shunro Tachibana Injection instrument with ultrasonic oscillating element
US5386837A (en) * 1993-02-01 1995-02-07 Mmtc, Inc. Method for enhancing delivery of chemotherapy employing high-frequency force fields
US5667487A (en) * 1993-04-07 1997-09-16 Henley; Julian L. Ionosonic drug delivery apparatus
US5490840A (en) * 1994-09-26 1996-02-13 General Electric Company Targeted thermal release of drug-polymer conjugates
US5752515A (en) * 1996-08-21 1998-05-19 Brigham & Women's Hospital Methods and apparatus for image-guided ultrasound delivery of compounds through the blood-brain barrier
WO1998018391A1 (fr) * 1996-10-30 1998-05-07 Ekos Corporation Dispositif d'administration de medicament par les parois intraluminales

Also Published As

Publication number Publication date
AU754022B2 (en) 2002-10-31
WO2000006032A1 (fr) 2000-02-10
EP1107702A1 (fr) 2001-06-20
AU5245099A (en) 2000-02-21
BR9912587A (pt) 2002-06-11
JP2002521118A (ja) 2002-07-16
EP1107702A4 (fr) 2002-10-09

Similar Documents

Publication Publication Date Title
AU754022B2 (en) Ultrasonic enhancement of drug injection
US20030009153A1 (en) Ultrasonic enhancement of drug injection
US6464680B1 (en) Ultrasonic enhancement of drug injection
US6484052B1 (en) Optically generated ultrasound for enhanced drug delivery
US7135029B2 (en) Ultrasonic surgical instrument for intracorporeal sonodynamic therapy
ES2293473T3 (es) Administracion intracardiaca de farmaco.
JP4860031B2 (ja) 心臓内細胞送達システムおよび方法
Huber et al. Focused ultrasound (HIFU) induces localized enhancement of reporter gene expression in rabbit carotid artery
US6575956B1 (en) Methods and apparatus for uniform transcutaneous therapeutic ultrasound
JP3980143B2 (ja) レーザ補助による薬剤のデリバリー装置
US6620123B1 (en) Method and apparatus for producing homogenous cavitation to enhance transdermal transport
JP3712668B2 (ja) 生体の目標組織に作用物質を送達するためのシステム
US20030229331A1 (en) Methods and apparatus for uniform transcutaneous therapeutic ultrasound
KR20040038758A (ko) 활성 치료제 또는 물질을 사용하여 조직의 목표 영역에배아 간상 세포를 안치시키는 방법
KR20040038757A (ko) 활성 치료제 또는 물질을 사용하여 조직의 목표 영역에도너 세포를 안치시키는 방법
AU2002316433A1 (en) An ultrasonic surgical instrument for intracorporeal sonodynamic therapy
JP2007289693A (ja) 超音波診断及び超音波治療を同時に実行する方法及び装置
JP4125130B2 (ja) 血管再生および薬剤送達用の超音波方法
WO2000048518A9 (fr) Methodes et appareil destines a la therapie transcutanee par champs uniforme d'ultrasons
US20040030250A1 (en) Injection system for gene delivery
Kalli et al. Introduction of genes via sonoporation and electroporation
Ho et al. Ultrasonic transdermal delivery system with acid–base neutralization-generated CO2 microbubble cavitation
Visuri et al. Optically generated ultrasound for enhanced drug delivery
US20090118673A1 (en) Needle injection catheter
Kost et al. 16 Ultrasound in Percutaneous Absorption

Legal Events

Date Code Title Description
FZDE Dead