CA2329075A1 - Carboxy substituted carboxamide derivatives as tachykinin receptor antagonists - Google Patents

Carboxy substituted carboxamide derivatives as tachykinin receptor antagonists Download PDF

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Publication number
CA2329075A1
CA2329075A1 CA002329075A CA2329075A CA2329075A1 CA 2329075 A1 CA2329075 A1 CA 2329075A1 CA 002329075 A CA002329075 A CA 002329075A CA 2329075 A CA2329075 A CA 2329075A CA 2329075 A1 CA2329075 A1 CA 2329075A1
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CA
Canada
Prior art keywords
receptor antagonists
carboxamide derivatives
carboxy substituted
tachykinin receptor
substituted carboxamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002329075A
Other languages
French (fr)
Other versions
CA2329075C (en
Inventor
George D. Maynard
Elizabeth M. Kudlacz
Timothy P. Burkholder
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Aventis Pharmaceuticals Inc
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Individual
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Publication date
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Priority claimed from PCT/US1999/009450 external-priority patent/WO1999059972A1/en
Publication of CA2329075A1 publication Critical patent/CA2329075A1/en
Application granted granted Critical
Publication of CA2329075C publication Critical patent/CA2329075C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to novel carboxy substituted acyclic carboxamide derivatives of formula (1), and stereoisomers and pharmaceutically acceptable salts thereof and their use as tachykinin receptor antagonists. Such antagonists are useful in the treatment of tachykinin-mediated diseases and conditions disclosed herein including:
asthma, cough, and bronchitis.
CA002329075A 1998-05-15 1999-04-30 Carboxy substituted carboxamide derivatives as tachykinin receptor antagonists Expired - Fee Related CA2329075C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12644798P 1998-05-15 1998-05-15
US60/126,447 1998-05-15
PCT/US1999/009450 WO1999059972A1 (en) 1998-05-15 1999-04-30 Carboxy substituted carboxamide derivatives as tachykinin receptor antagonists

Publications (2)

Publication Number Publication Date
CA2329075A1 true CA2329075A1 (en) 1999-11-25
CA2329075C CA2329075C (en) 2005-10-18

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ID=35285486

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002329075A Expired - Fee Related CA2329075C (en) 1998-05-15 1999-04-30 Carboxy substituted carboxamide derivatives as tachykinin receptor antagonists

Country Status (1)

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CA (1) CA2329075C (en)

Also Published As

Publication number Publication date
CA2329075C (en) 2005-10-18

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Legal Events

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EEER Examination request
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Effective date: 20080430