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Aventis Pharmaceuticals Inc
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Individual
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Priority claimed from PCT/US1999/009450external-prioritypatent/WO1999059972A1/en
Publication of CA2329075A1publicationCriticalpatent/CA2329075A1/en
Application grantedgrantedCritical
Publication of CA2329075CpublicationCriticalpatent/CA2329075C/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Abstract
The present invention relates to novel carboxy substituted acyclic carboxamide derivatives of formula (1), and stereoisomers and pharmaceutically acceptable salts thereof and their use as tachykinin receptor antagonists. Such antagonists are useful in the treatment of tachykinin-mediated diseases and conditions disclosed herein including: asthma, cough, and bronchitis.