CA2302630A1 - Purine acyclonucleosides as antiviral agents - Google Patents

Purine acyclonucleosides as antiviral agents Download PDF

Info

Publication number
CA2302630A1
CA2302630A1 CA002302630A CA2302630A CA2302630A1 CA 2302630 A1 CA2302630 A1 CA 2302630A1 CA 002302630 A CA002302630 A CA 002302630A CA 2302630 A CA2302630 A CA 2302630A CA 2302630 A1 CA2302630 A1 CA 2302630A1
Authority
CA
Canada
Prior art keywords
hydroxy
amino
hydrogen
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002302630A
Other languages
English (en)
French (fr)
Inventor
Karen Elizabeth Jarvis
Sebastian Mario Marcuccio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commonwealth Scientific and Industrial Research Organization CSIRO
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2302630A1 publication Critical patent/CA2302630A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/36—Sulfur atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002302630A 1997-09-11 1998-09-11 Purine acyclonucleosides as antiviral agents Abandoned CA2302630A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPO9129A AUPO912997A0 (en) 1997-09-11 1997-09-11 Antiviral agents
AUPO9129 1997-09-11
PCT/AU1998/000748 WO1999012927A1 (en) 1997-09-11 1998-09-11 Purine acyclonucleosides as antiviral agents

Publications (1)

Publication Number Publication Date
CA2302630A1 true CA2302630A1 (en) 1999-03-18

Family

ID=3803414

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002302630A Abandoned CA2302630A1 (en) 1997-09-11 1998-09-11 Purine acyclonucleosides as antiviral agents

Country Status (9)

Country Link
EP (1) EP1019404A4 (de)
JP (1) JP2001515900A (de)
KR (1) KR20010023890A (de)
CN (1) CN1269801A (de)
AU (1) AUPO912997A0 (de)
CA (1) CA2302630A1 (de)
ID (1) ID26937A (de)
NZ (1) NZ502994A (de)
WO (1) WO1999012927A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI20022A (sl) * 1998-07-29 2000-02-29 Kemijski inštitut Alkilno substituirani purinovi derivati in njihova priprava
KR100377138B1 (ko) * 1998-11-10 2003-06-12 주식회사 엘지생명과학 퓨린구조를갖는싸이클린의존키나아제저해제,그제조방법및그를함유하는항암제조성물
GB9903762D0 (en) 1999-02-18 1999-04-14 Novartis Ag Organic compounds
AU2001253226B2 (en) * 2000-04-07 2006-06-08 University Of Maryland, Baltimore Bile acid containing prodrugs with enhanced bioavailability
AU2002343604C1 (en) 2001-10-30 2009-09-17 Conforma Therapeutics Corporation Purine analogs having HSP90-inhibiting activity
ES2283788T3 (es) * 2002-06-27 2007-11-01 F. Hoffmann-La Roche Ag Sintesis de derivados de purina.
WO2004094426A1 (en) * 2003-04-21 2004-11-04 Ustav Organické Chemie A Biochemie Akademie Ved Ceské Republiky (purin-6-yl) amino acid and production method thereof
CN101906106A (zh) 2003-09-18 2010-12-08 康福玛医药公司 作为hsp90-抑制剂的新的杂环化合物
US7544672B2 (en) 2005-03-30 2009-06-09 Conforma Therapeutics Corporation Alkynyl pyrrolo[2,3-d]pyrimidines and related analogs as HSP90-inhibitors
CN102002043B (zh) * 2010-11-16 2012-10-24 江苏科技大学 4-氨基吡啶催化下的6-甲氧基嘌呤衍生物的合成方法
CN102633767B (zh) * 2012-04-09 2013-10-30 武汉工程大学 一种非离子型碘造影剂中间体2－异丙基－5－羧基－1，3－二氧六环的制备方法
NZ750604A (en) * 2016-08-29 2024-02-23 Hoffmann La Roche Novel 7-substituted sulfonimidoylpurinone compounds and derivatives for the treatment and prophylaxis of virus infection

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216141A (en) * 1988-06-06 1993-06-01 Benner Steven A Oligonucleotide analogs containing sulfur linkages
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment

Also Published As

Publication number Publication date
KR20010023890A (ko) 2001-03-26
CN1269801A (zh) 2000-10-11
EP1019404A4 (de) 2001-07-04
WO1999012927A1 (en) 1999-03-18
EP1019404A1 (de) 2000-07-19
AUPO912997A0 (en) 1997-10-02
ID26937A (id) 2001-02-22
NZ502994A (en) 2001-12-21
JP2001515900A (ja) 2001-09-25

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Legal Events

Date Code Title Description
FZDE Discontinued