CA2121121C - Preparation of recombinant borrelia proteins - Google Patents

Preparation of recombinant borrelia proteins Download PDF

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Publication number
CA2121121C
CA2121121C CA002121121A CA2121121A CA2121121C CA 2121121 C CA2121121 C CA 2121121C CA 002121121 A CA002121121 A CA 002121121A CA 2121121 A CA2121121 A CA 2121121A CA 2121121 C CA2121121 C CA 2121121C
Authority
CA
Canada
Prior art keywords
ospa
lipoprotein
protein
phase
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002121121A
Other languages
English (en)
French (fr)
Other versions
CA2121121A1 (en
Inventor
Lorne F. Erdile
Mary-Ann Brandt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Inc
Original Assignee
Connaught Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Connaught Laboratories Inc filed Critical Connaught Laboratories Inc
Publication of CA2121121A1 publication Critical patent/CA2121121A1/en
Application granted granted Critical
Publication of CA2121121C publication Critical patent/CA2121121C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002121121A 1991-10-18 1992-10-16 Preparation of recombinant borrelia proteins Expired - Fee Related CA2121121C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US77904891A 1991-10-18 1991-10-18
US779,048 1991-10-18
US88876592A 1992-05-27 1992-05-27
US888,765 1992-05-27
PCT/US1992/008697 WO1993008299A1 (en) 1991-10-18 1992-10-16 Preparation of recombinant borrelia proteins

Publications (2)

Publication Number Publication Date
CA2121121A1 CA2121121A1 (en) 1993-04-29
CA2121121C true CA2121121C (en) 2003-06-10

Family

ID=27119531

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002121121A Expired - Fee Related CA2121121C (en) 1991-10-18 1992-10-16 Preparation of recombinant borrelia proteins

Country Status (9)

Country Link
EP (1) EP0620860A4 (sv)
JP (1) JPH06511154A (sv)
AU (1) AU676140B2 (sv)
CA (1) CA2121121C (sv)
FI (1) FI941749A (sv)
IL (1) IL103462A0 (sv)
NO (1) NO310417B1 (sv)
PT (1) PT100980B (sv)
WO (1) WO1993008299A1 (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4015911A1 (de) * 1989-09-19 1991-03-28 Max Planck Gesellschaft Impfstoff gegen die lyme-krankheit
ATE181572T1 (de) * 1991-08-15 1999-07-15 Smithkline Beecham Biolog Ospa proteine von borrelia burgdorferi untergruppen, dafür kodierende gene sowie impfstoffe
US6676942B1 (en) 1991-08-15 2004-01-13 Smithkline Beecham Biologicals (S.A.) Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines
CA2105629A1 (en) * 1992-09-14 1994-03-15 Robert S. Becker Potentiation of immunogenic response
US7008625B2 (en) 1993-11-01 2006-03-07 Research Foundation Of The State University Of New York Recombinant constructs of Borrelia burgdorferi
US6248562B1 (en) 1993-11-01 2001-06-19 Research Foundation State University Of New York Chimeric proteins comprising borrelia polypeptides and uses therefor
US6610838B1 (en) 1997-09-10 2003-08-26 Symbicom Aktiebolag P13 antigens from Borrelia
US6224882B1 (en) 1997-11-07 2001-05-01 Protein Science Corp. Insect cells or fractions as adjuvant for antigens
GB9811219D0 (en) * 1998-05-26 1998-07-22 Smithkline Beecham Biolog Novel process
WO2000063386A2 (en) * 1999-04-21 2000-10-26 Boston Medical Center Corporation Prevention, diagnosis and treatment of lyme disease
ES2298249T3 (es) 2000-08-18 2008-05-16 Research Foundation Of State University Of New York Ospa modificada de borrelia burgdorferi.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK590288D0 (da) * 1988-10-24 1988-10-24 Symbicom Ab Kemiske forbindelser
DE4015911A1 (de) * 1989-09-19 1991-03-28 Max Planck Gesellschaft Impfstoff gegen die lyme-krankheit
ATE140461T1 (de) * 1989-12-22 1996-08-15 Mikrogen Molekularbiol Entw Immunologisch aktive proteine von borrelia burgdorferi, zusammenhängende testkits und impfstoff
CA2057536C (en) * 1990-12-21 1999-10-26 John J. Dunn Cloning and expression of borrelia lipoproteins
ATE181572T1 (de) * 1991-08-15 1999-07-15 Smithkline Beecham Biolog Ospa proteine von borrelia burgdorferi untergruppen, dafür kodierende gene sowie impfstoffe

Also Published As

Publication number Publication date
AU676140B2 (en) 1997-03-06
EP0620860A4 (en) 1997-05-02
NO310417B1 (no) 2001-07-02
WO1993008299A1 (en) 1993-04-29
EP0620860A1 (en) 1994-10-26
FI941749A0 (sv) 1994-04-15
IL103462A0 (en) 1993-03-15
CA2121121A1 (en) 1993-04-29
NO941376L (no) 1994-06-17
PT100980A (pt) 1994-01-31
AU2801192A (en) 1993-05-21
NO941376D0 (no) 1994-04-15
JPH06511154A (ja) 1994-12-15
PT100980B (pt) 1999-07-30
FI941749A (sv) 1994-05-25

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