CA2071871A1 - Muteines inhibitrices c1 et leur utilisation - Google Patents

Muteines inhibitrices c1 et leur utilisation

Info

Publication number
CA2071871A1
CA2071871A1 CA002071871A CA2071871A CA2071871A1 CA 2071871 A1 CA2071871 A1 CA 2071871A1 CA 002071871 A CA002071871 A CA 002071871A CA 2071871 A CA2071871 A CA 2071871A CA 2071871 A1 CA2071871 A1 CA 2071871A1
Authority
CA
Canada
Prior art keywords
inhibitor
muteins
recombinant
replaced
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002071871A
Other languages
English (en)
Inventor
Eric Eldering
Lucien Aarden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2071871A1 publication Critical patent/CA2071871A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002071871A 1989-10-27 1990-10-22 Muteines inhibitrices c1 et leur utilisation Abandoned CA2071871A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42820289A 1989-10-27 1989-10-27
US428,202 1989-10-27

Publications (1)

Publication Number Publication Date
CA2071871A1 true CA2071871A1 (fr) 1991-04-28

Family

ID=23697954

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002071871A Abandoned CA2071871A1 (fr) 1989-10-27 1990-10-22 Muteines inhibitrices c1 et leur utilisation

Country Status (5)

Country Link
EP (1) EP0497833A1 (fr)
JP (1) JPH05503001A (fr)
AU (1) AU658560B2 (fr)
CA (1) CA2071871A1 (fr)
WO (1) WO1991006650A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992022320A1 (fr) * 1991-06-14 1992-12-23 Genentech, Inc. Variantes de l'inhibiteur c1 et traitement des reactions inflammatoires avec l'inhibiteur c1
EP0716611B1 (fr) * 1993-09-01 2002-02-06 Stichting Sanquin Bloedvoorziening Inhibiteur de l'esterase de c1 pour reduire des lesions du myocarde au cours d'un infarctus du myocarde aigu
DE19829014A1 (de) * 1998-06-30 2000-01-05 Centeon Pharma Gmbh Modifizierter C1-Esterase-Inhibitor zur Blockierung der Infektiosität von HIV
AU2006203549B2 (en) * 2000-01-31 2008-10-09 Pharming Intellectual Property B.V. C1 inhibitor produced in the milk of transgenic mammals
US7067713B2 (en) 2000-01-31 2006-06-27 Pharming Intellectual Property B.V. C1 Inhibitor produced in the milk of transgenic non-human mammals
EP1252184B1 (fr) * 2000-01-31 2008-01-02 Pharming Intellectual Property B.V. Inhibiteur de c1 human produit dans du lait de mammiferes transgeniques
PL1626736T3 (pl) 2003-05-16 2021-05-04 Pharming Intellectual Property B.V. Inhibitor c1 o krótkim okresie półtrwania do leczenia przejściowego
EP1675597A2 (fr) * 2003-10-21 2006-07-05 Aga Ab Utilisation du xenon pou la prévention de la mort cellulaire programmée
CA3154415A1 (fr) 2006-10-10 2008-04-17 Regenesance B.V. Oligonucleotide antisens destine a l'utilisation dans la facilitation de la regeneration axonale

Also Published As

Publication number Publication date
AU6611290A (en) 1991-05-31
JPH05503001A (ja) 1993-05-27
EP0497833A1 (fr) 1992-08-12
AU658560B2 (en) 1995-04-27
WO1991006650A1 (fr) 1991-05-16

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Legal Events

Date Code Title Description
FZDE Dead