CA2070989A1 - Production de muteine du fgf de base humain - Google Patents

Production de muteine du fgf de base humain

Info

Publication number: CA2070989A1
Authority: CA; Canada
Prior art keywords: mutein; amino acid; hbfgf; transformant; iptg
Prior art date: 1989-12-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002070989A

Other languages

English (en)

Inventor

Kazuaki Kitano

Masato Kuriyama

Osamu Nishimura

Koichi Igarashi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Takeda Pharmaceutical Co Ltd

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-19

Filing date

1990-12-18

Publication date

1991-06-20

1990-12-18 Application filed by Individual filed Critical Individual

1991-06-20 Publication of CA2070989A1 publication Critical patent/CA2070989A1/fr

Status Abandoned legal-status Critical Current

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C07K14/503—Fibroblast growth factor [FGF] basic FGF [bFGF]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Mycology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Microbiology (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Botany (AREA)
Tropical Medicine & Parasitology (AREA)
Virology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

CA002070989A 1989-12-19 1990-12-18 Production de muteine du fgf de base humain Abandoned CA2070989A1 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP33022589		1989-12-19
JP1-330225/1989		1989-12-19
PCT/JP1990/001646 WO1991009126A1 (fr)	1989-12-19	1990-12-18	Production d'une muteine du facteur de croissance fibroblastique basique de l'homme

Publications (1)

Publication Number	Publication Date
CA2070989A1 true CA2070989A1 (fr)	1991-06-20

Family

ID=18230255

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002070989A Abandoned CA2070989A1 (fr)	1989-12-19	1990-12-18	Production de muteine du fgf de base humain

Country Status (7)

Country	Link
EP (1)	EP0506963A1 (fr)
JP (1)	JP3130313B2 (fr)
KR (1)	KR920703789A (fr)
CN (1)	CN1055009A (fr)
CA (1)	CA2070989A1 (fr)
HU (1)	HUT64593A (fr)
WO (1)	WO1991009126A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100374310B1 (ko) *	1995-02-14	2003-05-22	주식회사 엘지생명과학	변형된인간염기성섬유아세포성장인자및이의생산방법
US6274712B1 (en)	1997-12-23	2001-08-14	3-Dimensional Pharmaceuticals, Inc.	Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamute 89, aspartate 101 or leucine 137
AU2002236477A1 (en) *	2000-11-21	2002-06-03	The Texas A & M University System	Fgf-affinity chromatography
JP2009508596A (ja)	2005-09-19	2009-03-05	ヒストジェニックスコーポレイション	細胞支持基材及びその調製方法
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DE102021211272A1 (de)	2021-10-06	2023-04-06	Ruhr-Universität Bochum, Körperschaft des öffentlichen Rechts	Zusammensetzung enthaltend künstliche Sauerstoffträger zur Verhinderung von Organschäden in Transplantationsorganen

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EP0326907A1 (fr) *	1988-01-26	1989-08-09	Takeda Chemical Industries, Ltd.	Polypeptide, DNA et leur utilisation

1990
- 1990-12-18 CA CA002070989A patent/CA2070989A1/fr not_active Abandoned
- 1990-12-18 JP JP03501005A patent/JP3130313B2/ja not_active Expired - Fee Related
- 1990-12-18 EP EP91900328A patent/EP0506963A1/fr not_active Withdrawn
- 1990-12-18 WO PCT/JP1990/001646 patent/WO1991009126A1/fr not_active Application Discontinuation
- 1990-12-18 KR KR1019920701470A patent/KR920703789A/ko not_active IP Right Cessation
- 1990-12-18 HU HU9202039A patent/HUT64593A/hu unknown
- 1990-12-19 CN CN90110115A patent/CN1055009A/zh active Pending

Also Published As

Publication number	Publication date
HUT64593A (en)	1994-01-28
JPH05503006A (ja)	1993-05-27
HU9202039D0 (en)	1992-09-28
KR920703789A (ko)	1992-12-18
CN1055009A (zh)	1991-10-02
EP0506963A1 (fr)	1992-10-07
WO1991009126A1 (fr)	1991-06-27
JP3130313B2 (ja)	2001-01-31

Legal Events

Date	Code	Title	Description
1996-06-18	FZDE	Dead

Publication	Publication Date	Title
EP0503297B1 (fr)	1999-07-14	Facteur d'activation des cellules gliales et sa production
US5670338A (en)	1997-09-23	DNA encoding bone morphogenetic proteins, host cells transformed there by, and uses thereof
US5559093A (en)	1996-09-24	N-terminally truncated hst-1 is a platelet-increasing factor
EP0293793A2 (fr)	1988-12-07	Polypeptide et sa production
US5851990A (en)	1998-12-22	bFGF mutein and its production
CA2070989A1 (fr)	1991-06-20	Production de muteine du fgf de base humain
US5750371A (en)	1998-05-12	Water-soluble mutein of FGF receptor, DNA and production thereof
US5120715A (en)	1992-06-09	Method for purifying fibroblast growth factor protein
JPH05271279A (ja)	1993-10-19	ヒト副甲状腺ホルモンムテインおよびその製造法
CA2027075C (fr)	2002-11-26	Muteine de hst-1 et sa production
US5395756A (en)	1995-03-07	Production of acidic FGF protein
EP0529076B1 (fr)	1995-12-06	Proteines presentant une activite de recepteur de facteur de croissance de fibroblaste
JP3287869B2 (ja)	2002-06-04	ヒト神経成長因子２の製造法
US5679550A (en)	1997-10-21	Hst-2 muteins, pharmaceutical compositions and kits comprising same, and preparation of same
EP0406738A2 (fr)	1991-01-09	Préparation du facteur acide de croissance des fibrolastes
EP0528271A1 (fr)	1993-02-24	Mutéines de l'hormone parathyroidienne humaine et leur production
EP0488196A2 (fr)	1992-06-03	HST-2, un membre de la famille des facteurs de croissance liant l'héparine
JPH04164096A (ja)	1992-06-09	ａＦＧＦムテイン，ＤＮＡおよびその用途
JPH0541988A (ja)	1993-02-23	ラツトｂＦＧＦ蛋白質の製造法
AU607129B2 (en)	1991-02-28	Human basic fibroblast growth factor (hbFGF) and method of production thereof using genetic engineering techniques
JPH03184998A (ja)	1991-08-12	ハイブリッド蛋白質，ｄｎａおよびその用途
CA2010593A1 (fr)	1990-08-31	Obtention d'un nouveau polypeptide
JPH07126293A (ja)	1995-05-16	ｈｓｔ−２ムテイン、その製造法および用途