CA2063791A1 - Capsule de gelatine dure renfermant des nutriments liposolubles - Google Patents
Capsule de gelatine dure renfermant des nutriments liposolublesInfo
- Publication number
- CA2063791A1 CA2063791A1 CA2063791A CA2063791A CA2063791A1 CA 2063791 A1 CA2063791 A1 CA 2063791A1 CA 2063791 A CA2063791 A CA 2063791A CA 2063791 A CA2063791 A CA 2063791A CA 2063791 A1 CA2063791 A1 CA 2063791A1
- Authority
- CA
- Canada
- Prior art keywords
- fat
- soluble
- containing fat
- capsule containing
- soluble nutrients
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000015097 nutrients Nutrition 0.000 title abstract 3
- 229920000159 gelatin Polymers 0.000 title abstract 2
- 235000019322 gelatine Nutrition 0.000 title abstract 2
- 239000001828 Gelatine Substances 0.000 title 1
- 239000002775 capsule Substances 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- 239000007903 gelatin capsule Substances 0.000 abstract 2
- 239000000263 2,3-dihydroxypropyl (Z)-octadec-9-enoate Substances 0.000 abstract 1
- RZRNAYUHWVFMIP-GDCKJWNLSA-N 3-oleoyl-sn-glycerol Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](O)CO RZRNAYUHWVFMIP-GDCKJWNLSA-N 0.000 abstract 1
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 239000004902 Softening Agent Substances 0.000 abstract 1
- 239000004359 castor oil Substances 0.000 abstract 1
- 235000019438 castor oil Nutrition 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 abstract 1
- RZRNAYUHWVFMIP-UHFFFAOYSA-N monoelaidin Natural products CCCCCCCCC=CCCCCCCCC(=O)OCC(O)CO RZRNAYUHWVFMIP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 150000003722 vitamin derivatives Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nutrition Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- General Preparation And Processing Of Foods (AREA)
Abstract
Capsules dures de gélatine contenant: (a) un nutriment soluble dans la matière grasse, tel qu'une vitamine (A, D, E ou K) soluble dans de la matière grasse ou un glycéride d'acide gras insaturé; (b) un tensio-actif non ionique tel qu'une huile de ricin polyoxyéthylée (facultativement hydrogénée), et/ou un polyéthylène glycol; (c) un agent adoucissant la gélatine tel que le glycérol, le propylène glycol ou, de préférence, du mono-oléate de glycéryle; et facultativement (d) de l'eau. Ainsi, on réduit ou on évite les problèmes de fragilité rencontrés habituellement avec les capsules dures de gélatine contenant des nutriments solubles dans la matière grasse.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8918809.8 | 1989-08-17 | ||
GB898918809A GB8918809D0 (en) | 1989-08-17 | 1989-08-17 | Pharmaceutical formulations |
PCT/GB1990/001299 WO1991002520A1 (fr) | 1989-08-17 | 1990-08-17 | Compositions pharmaceutiques |
US08/430,500 US5738871A (en) | 1989-08-17 | 1995-04-28 | Pharmaceutical formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2063791A1 true CA2063791A1 (fr) | 1991-02-18 |
CA2063791C CA2063791C (fr) | 2000-12-19 |
Family
ID=26295779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002063791A Expired - Lifetime CA2063791C (fr) | 1989-08-17 | 1990-08-17 | Capsule de gelatine dure renfermant des nutriments liposolubles |
Country Status (13)
Country | Link |
---|---|
US (1) | US5738871A (fr) |
EP (1) | EP0487575B1 (fr) |
JP (1) | JPH04507418A (fr) |
AT (1) | ATE113471T1 (fr) |
AU (1) | AU633959B2 (fr) |
CA (1) | CA2063791C (fr) |
DE (1) | DE69013923T2 (fr) |
DK (1) | DK0487575T3 (fr) |
ES (1) | ES2062543T3 (fr) |
FI (1) | FI920646A0 (fr) |
HK (1) | HK85196A (fr) |
NO (1) | NO302333B1 (fr) |
WO (1) | WO1991002520A1 (fr) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2281697A (en) * | 1993-09-14 | 1995-03-15 | Euro Celtique Sa | Laxative compositions in capsules |
ES2308955T5 (es) * | 1993-09-28 | 2012-04-03 | R.P. Scherer Gmbh | Fabricación de cápsulas de gelatina blanda |
GB9325445D0 (en) | 1993-12-13 | 1994-02-16 | Cortecs Ltd | Pharmaceutical formulations |
US5567592A (en) * | 1994-02-02 | 1996-10-22 | Regents Of The University Of California | Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal |
GB9405304D0 (en) * | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
CA2236089C (fr) * | 1995-11-24 | 2002-03-05 | Loders-Croklaan B.V. | Composition a base d'huiles de poisson |
US6056971A (en) * | 1996-07-24 | 2000-05-02 | Biosytes Usa, Inc. | Method for enhancing dissolution properties of relatively insoluble dietary supplements and product incorporating same |
GB9705813D0 (en) * | 1997-03-20 | 1997-05-07 | Smithkline Beecham Plc | Novel compositions |
AUPP022297A0 (en) | 1997-11-06 | 1997-11-27 | R.P. Scherer Holdings Pty Ltd | Vitamin coating |
TW367247B (en) * | 1998-02-03 | 1999-08-21 | Otsuka Pharma Co Ltd | Storage container for Vitamin D solution and transfusion container |
US6652880B1 (en) | 1999-04-01 | 2003-11-25 | R.P. Scherer Technologies, Inc. | Oral pharmaceutical compositions containing long-chain triglycerides and liphophilic surfactants |
US6346231B1 (en) * | 1999-10-06 | 2002-02-12 | Joar Opheim | Flavored gelatin capsule and method of manufacture |
US6365181B1 (en) | 2000-04-20 | 2002-04-02 | Gattefosse Corporation | Thixatropic gelatin carrier composition |
GB0101198D0 (en) | 2001-01-17 | 2001-02-28 | Scherer Technologies Inc R P | Ingestible compositions containing an odoriferous oil |
AUPR510001A0 (en) * | 2001-05-18 | 2001-06-14 | Jupitar Pty Ltd | Formulation and method |
NZ536267A (en) * | 2002-04-10 | 2007-06-29 | Fred H Miller | Multi-phase, multi-compartment and multi-ingredient capsular system |
US7670612B2 (en) * | 2002-04-10 | 2010-03-02 | Innercap Technologies, Inc. | Multi-phase, multi-compartment capsular delivery apparatus and methods for using same |
EP1589930A2 (fr) * | 2003-01-08 | 2005-11-02 | Flacco-Nesselroad Family Trust | Therapie combinee anticoagulante |
JP2005075804A (ja) * | 2003-09-03 | 2005-03-24 | Toyo Capsule Kk | メナテトレノン含有医薬組成物 |
WO2005089716A1 (fr) * | 2004-03-24 | 2005-09-29 | Takeda Pharmaceutical Company Limited | Préparation en teneur élevée |
US8241670B2 (en) | 2004-04-15 | 2012-08-14 | Chiasma Inc. | Compositions capable of facilitating penetration across a biological barrier |
AU2005279201B2 (en) * | 2004-08-31 | 2011-08-04 | Akzo Nobel N.V. | Method for pigment solubilisation, a pigment composition and its use |
CA2659206A1 (fr) * | 2006-06-27 | 2008-01-03 | Akzo Nobel N.V. | Formulations comprenant une vitamine et utilisation de celles-ci pour fabriquer une nourriture pour animaux enrichie et des formulations de soin personnel |
EP2214481B1 (fr) | 2007-10-15 | 2019-05-01 | United Animal Health, Inc. | Procédé permettant d'accroître la performance d'une progéniture |
EP2296682B8 (fr) | 2008-04-29 | 2018-07-04 | Nikken Sohonsha Corporation | Procédés de traitement de troubles ophtalmiques |
JP6063615B2 (ja) * | 2008-04-29 | 2017-01-18 | 株式会社日健総本社 | 眼の医学的症状の治療用組成物 |
MX348705B (es) | 2008-09-17 | 2017-06-26 | Chiasma Inc | Composiciones farmacéuticas y métodos de administración relacionados. |
EP2405902B1 (fr) | 2009-03-09 | 2021-07-21 | Basf As | Compositions comprenant un mélange d'huile d'acide gras et d'agent tensio-actif, et leurs procédés et utilisations |
US8197871B2 (en) * | 2009-05-13 | 2012-06-12 | L Europa Gary A | Composition for headache treatment |
KR20200013123A (ko) * | 2009-10-23 | 2020-02-05 | 바스프 에이에스 | 지방산 오일 혼합물의 코팅된 캡슐 및 정제 |
US10610528B2 (en) * | 2009-12-08 | 2020-04-07 | Intelgenx Corp. | Solid oral film dosage forms and methods for making same |
ES2610907T3 (es) | 2010-09-07 | 2017-05-04 | Dsm Nutritional Products Ag | Emulsiones comestibles |
US8951514B2 (en) | 2011-02-16 | 2015-02-10 | Pivotal Therapeutics Inc. | Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels |
US8952000B2 (en) | 2011-02-16 | 2015-02-10 | Pivotal Therapeutics Inc. | Cholesterol absorption inhibitor and omega 3 fatty acids for the reduction of cholesterol and for the prevention or reduction of cardiovascular, cardiac and vascular events |
US9119826B2 (en) | 2011-02-16 | 2015-09-01 | Pivotal Therapeutics, Inc. | Omega 3 fatty acid for use as a prescription medical food and omega 3 fatty acid diagniostic assay for the dietary management of cardiovascular patients with cardiovascular disease (CVD) who are deficient in blood EPA and DHA levels |
US8715648B2 (en) | 2011-02-16 | 2014-05-06 | Pivotal Therapeutics Inc. | Method for treating obesity with anti-obesity formulations and omega 3 fatty acids for the reduction of body weight in cardiovascular disease patients (CVD) and diabetics |
CA2950670A1 (fr) | 2014-06-17 | 2015-12-23 | Merck Sharp & Dohme B.V. | Formulations stables d'undecanoate de testosterone |
WO2016126830A1 (fr) | 2015-02-03 | 2016-08-11 | Chiasma Inc. | Méthode de traitement de maladies |
US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
DE102021003906B4 (de) | 2021-07-30 | 2023-03-30 | Mirco Bienhaus | Verfahren und Vorrichtungen zur Herstellung fester oder halbfester Arzneiformen mit einem mehrschichtigen Aufbau |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5665820A (en) * | 1979-11-02 | 1981-06-03 | Eisai Co Ltd | Hard capsule with high content of tocopherol nicotinate |
DE3237814A1 (de) * | 1982-10-12 | 1984-04-12 | Warner-Lambert Co., 07950 Morris Plains, N.J. | Wasserfreie emulsionen und verwendung derselben |
AU561367B2 (en) * | 1983-05-02 | 1987-05-07 | Scherer, R.P. Pty. Ltd. | Vitamin composition with enhanced bioavailability |
US4572915A (en) * | 1984-05-01 | 1986-02-25 | Bioglan Laboratories | Clear micellized solutions of fat soluble essential nutrients |
JPS61221131A (ja) * | 1985-03-28 | 1986-10-01 | Eisai Co Ltd | 吸収促進したユビデカレノン含有組成物 |
US4795642A (en) * | 1986-05-01 | 1989-01-03 | Pharmacaps, Inc. | Gelatin-encapsulated controlled-release composition |
GB8630273D0 (en) * | 1986-12-18 | 1987-01-28 | Til Medical Ltd | Pharmaceutical delivery systems |
US4816259A (en) * | 1987-02-12 | 1989-03-28 | Chase Chemical Company, L.P. | Process for coating gelatin capsules |
NZ224497A (en) * | 1987-05-18 | 1990-04-26 | Janssen Pharmaceutica Nv | Pharmaceutical composition comprising flunarizine |
JPH01233218A (ja) * | 1988-03-15 | 1989-09-19 | Daikyo Yakuhin Kogyo Kk | ビタミン組成物 |
US5188688A (en) * | 1990-07-20 | 1993-02-23 | Minnesota Mining And Manufacturing Company | Method of sealing a gelatin capsule |
US5455045A (en) * | 1993-05-13 | 1995-10-03 | Syntex (U.S.A.) Inc. | High dose formulations |
-
1990
- 1990-08-17 DE DE69013923T patent/DE69013923T2/de not_active Expired - Fee Related
- 1990-08-17 ES ES90912234T patent/ES2062543T3/es not_active Expired - Lifetime
- 1990-08-17 DK DK90912234.3T patent/DK0487575T3/da active
- 1990-08-17 JP JP2511491A patent/JPH04507418A/ja active Pending
- 1990-08-17 WO PCT/GB1990/001299 patent/WO1991002520A1/fr active IP Right Grant
- 1990-08-17 AT AT90912234T patent/ATE113471T1/de not_active IP Right Cessation
- 1990-08-17 CA CA002063791A patent/CA2063791C/fr not_active Expired - Lifetime
- 1990-08-17 AU AU61619/90A patent/AU633959B2/en not_active Ceased
- 1990-08-17 EP EP90912234A patent/EP0487575B1/fr not_active Expired - Lifetime
-
1992
- 1992-02-14 FI FI920646A patent/FI920646A0/fi unknown
- 1992-02-14 NO NO920604A patent/NO302333B1/no unknown
-
1995
- 1995-04-28 US US08/430,500 patent/US5738871A/en not_active Expired - Fee Related
-
1996
- 1996-05-16 HK HK85196A patent/HK85196A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US5738871A (en) | 1998-04-14 |
ATE113471T1 (de) | 1994-11-15 |
CA2063791C (fr) | 2000-12-19 |
AU633959B2 (en) | 1993-02-11 |
DK0487575T3 (da) | 1994-11-28 |
NO920604D0 (no) | 1992-02-14 |
NO302333B1 (no) | 1998-02-23 |
ES2062543T3 (es) | 1994-12-16 |
EP0487575A1 (fr) | 1992-06-03 |
FI920646A0 (fi) | 1992-02-14 |
EP0487575B1 (fr) | 1994-11-02 |
HK85196A (en) | 1996-05-24 |
NO920604L (no) | 1992-02-14 |
AU6161990A (en) | 1991-04-03 |
JPH04507418A (ja) | 1992-12-24 |
DE69013923T2 (de) | 1995-03-16 |
DE69013923D1 (de) | 1994-12-08 |
WO1991002520A1 (fr) | 1991-03-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |