CA2063791A1 - Capsule de gelatine dure renfermant des nutriments liposolubles - Google Patents

Capsule de gelatine dure renfermant des nutriments liposolubles

Info

Publication number
CA2063791A1
CA2063791A1 CA2063791A CA2063791A CA2063791A1 CA 2063791 A1 CA2063791 A1 CA 2063791A1 CA 2063791 A CA2063791 A CA 2063791A CA 2063791 A CA2063791 A CA 2063791A CA 2063791 A1 CA2063791 A1 CA 2063791A1
Authority
CA
Canada
Prior art keywords
fat
soluble
containing fat
capsule containing
soluble nutrients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2063791A
Other languages
English (en)
Other versions
CA2063791C (fr
Inventor
Michael John Story
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PII Drug Delivery LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898918809A external-priority patent/GB8918809D0/en
Application filed by Individual filed Critical Individual
Publication of CA2063791A1 publication Critical patent/CA2063791A1/fr
Application granted granted Critical
Publication of CA2063791C publication Critical patent/CA2063791C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

Capsules dures de gélatine contenant: (a) un nutriment soluble dans la matière grasse, tel qu'une vitamine (A, D, E ou K) soluble dans de la matière grasse ou un glycéride d'acide gras insaturé; (b) un tensio-actif non ionique tel qu'une huile de ricin polyoxyéthylée (facultativement hydrogénée), et/ou un polyéthylène glycol; (c) un agent adoucissant la gélatine tel que le glycérol, le propylène glycol ou, de préférence, du mono-oléate de glycéryle; et facultativement (d) de l'eau. Ainsi, on réduit ou on évite les problèmes de fragilité rencontrés habituellement avec les capsules dures de gélatine contenant des nutriments solubles dans la matière grasse.
CA002063791A 1989-08-17 1990-08-17 Capsule de gelatine dure renfermant des nutriments liposolubles Expired - Lifetime CA2063791C (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8918809.8 1989-08-17
GB898918809A GB8918809D0 (en) 1989-08-17 1989-08-17 Pharmaceutical formulations
PCT/GB1990/001299 WO1991002520A1 (fr) 1989-08-17 1990-08-17 Compositions pharmaceutiques
US08/430,500 US5738871A (en) 1989-08-17 1995-04-28 Pharmaceutical formulations

Publications (2)

Publication Number Publication Date
CA2063791A1 true CA2063791A1 (fr) 1991-02-18
CA2063791C CA2063791C (fr) 2000-12-19

Family

ID=26295779

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002063791A Expired - Lifetime CA2063791C (fr) 1989-08-17 1990-08-17 Capsule de gelatine dure renfermant des nutriments liposolubles

Country Status (13)

Country Link
US (1) US5738871A (fr)
EP (1) EP0487575B1 (fr)
JP (1) JPH04507418A (fr)
AT (1) ATE113471T1 (fr)
AU (1) AU633959B2 (fr)
CA (1) CA2063791C (fr)
DE (1) DE69013923T2 (fr)
DK (1) DK0487575T3 (fr)
ES (1) ES2062543T3 (fr)
FI (1) FI920646A0 (fr)
HK (1) HK85196A (fr)
NO (1) NO302333B1 (fr)
WO (1) WO1991002520A1 (fr)

Families Citing this family (40)

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GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
ES2308955T5 (es) * 1993-09-28 2012-04-03 R.P. Scherer Gmbh Fabricación de cápsulas de gelatina blanda
GB9325445D0 (en) 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
US5567592A (en) * 1994-02-02 1996-10-22 Regents Of The University Of California Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
CA2236089C (fr) * 1995-11-24 2002-03-05 Loders-Croklaan B.V. Composition a base d'huiles de poisson
US6056971A (en) * 1996-07-24 2000-05-02 Biosytes Usa, Inc. Method for enhancing dissolution properties of relatively insoluble dietary supplements and product incorporating same
GB9705813D0 (en) * 1997-03-20 1997-05-07 Smithkline Beecham Plc Novel compositions
AUPP022297A0 (en) 1997-11-06 1997-11-27 R.P. Scherer Holdings Pty Ltd Vitamin coating
TW367247B (en) * 1998-02-03 1999-08-21 Otsuka Pharma Co Ltd Storage container for Vitamin D solution and transfusion container
US6652880B1 (en) 1999-04-01 2003-11-25 R.P. Scherer Technologies, Inc. Oral pharmaceutical compositions containing long-chain triglycerides and liphophilic surfactants
US6346231B1 (en) * 1999-10-06 2002-02-12 Joar Opheim Flavored gelatin capsule and method of manufacture
US6365181B1 (en) 2000-04-20 2002-04-02 Gattefosse Corporation Thixatropic gelatin carrier composition
GB0101198D0 (en) 2001-01-17 2001-02-28 Scherer Technologies Inc R P Ingestible compositions containing an odoriferous oil
AUPR510001A0 (en) * 2001-05-18 2001-06-14 Jupitar Pty Ltd Formulation and method
NZ536267A (en) * 2002-04-10 2007-06-29 Fred H Miller Multi-phase, multi-compartment and multi-ingredient capsular system
US7670612B2 (en) * 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
EP1589930A2 (fr) * 2003-01-08 2005-11-02 Flacco-Nesselroad Family Trust Therapie combinee anticoagulante
JP2005075804A (ja) * 2003-09-03 2005-03-24 Toyo Capsule Kk メナテトレノン含有医薬組成物
WO2005089716A1 (fr) * 2004-03-24 2005-09-29 Takeda Pharmaceutical Company Limited Préparation en teneur élevée
US8241670B2 (en) 2004-04-15 2012-08-14 Chiasma Inc. Compositions capable of facilitating penetration across a biological barrier
AU2005279201B2 (en) * 2004-08-31 2011-08-04 Akzo Nobel N.V. Method for pigment solubilisation, a pigment composition and its use
CA2659206A1 (fr) * 2006-06-27 2008-01-03 Akzo Nobel N.V. Formulations comprenant une vitamine et utilisation de celles-ci pour fabriquer une nourriture pour animaux enrichie et des formulations de soin personnel
EP2214481B1 (fr) 2007-10-15 2019-05-01 United Animal Health, Inc. Procédé permettant d'accroître la performance d'une progéniture
EP2296682B8 (fr) 2008-04-29 2018-07-04 Nikken Sohonsha Corporation Procédés de traitement de troubles ophtalmiques
JP6063615B2 (ja) * 2008-04-29 2017-01-18 株式会社日健総本社 眼の医学的症状の治療用組成物
MX348705B (es) 2008-09-17 2017-06-26 Chiasma Inc Composiciones farmacéuticas y métodos de administración relacionados.
EP2405902B1 (fr) 2009-03-09 2021-07-21 Basf As Compositions comprenant un mélange d'huile d'acide gras et d'agent tensio-actif, et leurs procédés et utilisations
US8197871B2 (en) * 2009-05-13 2012-06-12 L Europa Gary A Composition for headache treatment
KR20200013123A (ko) * 2009-10-23 2020-02-05 바스프 에이에스 지방산 오일 혼합물의 코팅된 캡슐 및 정제
US10610528B2 (en) * 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
ES2610907T3 (es) 2010-09-07 2017-05-04 Dsm Nutritional Products Ag Emulsiones comestibles
US8951514B2 (en) 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels
US8952000B2 (en) 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Cholesterol absorption inhibitor and omega 3 fatty acids for the reduction of cholesterol and for the prevention or reduction of cardiovascular, cardiac and vascular events
US9119826B2 (en) 2011-02-16 2015-09-01 Pivotal Therapeutics, Inc. Omega 3 fatty acid for use as a prescription medical food and omega 3 fatty acid diagniostic assay for the dietary management of cardiovascular patients with cardiovascular disease (CVD) who are deficient in blood EPA and DHA levels
US8715648B2 (en) 2011-02-16 2014-05-06 Pivotal Therapeutics Inc. Method for treating obesity with anti-obesity formulations and omega 3 fatty acids for the reduction of body weight in cardiovascular disease patients (CVD) and diabetics
CA2950670A1 (fr) 2014-06-17 2015-12-23 Merck Sharp & Dohme B.V. Formulations stables d'undecanoate de testosterone
WO2016126830A1 (fr) 2015-02-03 2016-08-11 Chiasma Inc. Méthode de traitement de maladies
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods
DE102021003906B4 (de) 2021-07-30 2023-03-30 Mirco Bienhaus Verfahren und Vorrichtungen zur Herstellung fester oder halbfester Arzneiformen mit einem mehrschichtigen Aufbau

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5665820A (en) * 1979-11-02 1981-06-03 Eisai Co Ltd Hard capsule with high content of tocopherol nicotinate
DE3237814A1 (de) * 1982-10-12 1984-04-12 Warner-Lambert Co., 07950 Morris Plains, N.J. Wasserfreie emulsionen und verwendung derselben
AU561367B2 (en) * 1983-05-02 1987-05-07 Scherer, R.P. Pty. Ltd. Vitamin composition with enhanced bioavailability
US4572915A (en) * 1984-05-01 1986-02-25 Bioglan Laboratories Clear micellized solutions of fat soluble essential nutrients
JPS61221131A (ja) * 1985-03-28 1986-10-01 Eisai Co Ltd 吸収促進したユビデカレノン含有組成物
US4795642A (en) * 1986-05-01 1989-01-03 Pharmacaps, Inc. Gelatin-encapsulated controlled-release composition
GB8630273D0 (en) * 1986-12-18 1987-01-28 Til Medical Ltd Pharmaceutical delivery systems
US4816259A (en) * 1987-02-12 1989-03-28 Chase Chemical Company, L.P. Process for coating gelatin capsules
NZ224497A (en) * 1987-05-18 1990-04-26 Janssen Pharmaceutica Nv Pharmaceutical composition comprising flunarizine
JPH01233218A (ja) * 1988-03-15 1989-09-19 Daikyo Yakuhin Kogyo Kk ビタミン組成物
US5188688A (en) * 1990-07-20 1993-02-23 Minnesota Mining And Manufacturing Company Method of sealing a gelatin capsule
US5455045A (en) * 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations

Also Published As

Publication number Publication date
US5738871A (en) 1998-04-14
ATE113471T1 (de) 1994-11-15
CA2063791C (fr) 2000-12-19
AU633959B2 (en) 1993-02-11
DK0487575T3 (da) 1994-11-28
NO920604D0 (no) 1992-02-14
NO302333B1 (no) 1998-02-23
ES2062543T3 (es) 1994-12-16
EP0487575A1 (fr) 1992-06-03
FI920646A0 (fi) 1992-02-14
EP0487575B1 (fr) 1994-11-02
HK85196A (en) 1996-05-24
NO920604L (no) 1992-02-14
AU6161990A (en) 1991-04-03
JPH04507418A (ja) 1992-12-24
DE69013923T2 (de) 1995-03-16
DE69013923D1 (de) 1994-12-08
WO1991002520A1 (fr) 1991-03-07

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Legal Events

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