CA2014590A1 - Peptides et agents contre la demence les contenant - Google Patents

Peptides et agents contre la demence les contenant

Info

Publication number
CA2014590A1
CA2014590A1 CA2014590A CA2014590A CA2014590A1 CA 2014590 A1 CA2014590 A1 CA 2014590A1 CA 2014590 A CA2014590 A CA 2014590A CA 2014590 A CA2014590 A CA 2014590A CA 2014590 A1 CA2014590 A1 CA 2014590A1
Authority
CA
Canada
Prior art keywords
pro
arg
asn
gly
ser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2014590A
Other languages
English (en)
Other versions
CA2014590C (fr
Inventor
Mitsuo Masaki
Masaki Uehara
Kenji Hirate
Yoshikazu Isowa
Yoshiaki Sato
Yoshiharu Nakashima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Chemiphar Co Ltd
Original Assignee
Mitsuo Masaki
Masaki Uehara
Kenji Hirate
Yoshikazu Isowa
Yoshiaki Sato
Yoshiharu Nakashima
Fujirebio Kabushiki Kaisha
Nippon Chemiphar Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1095918A external-priority patent/JP2542254B2/ja
Priority claimed from JP1095917A external-priority patent/JP2640778B2/ja
Priority claimed from JP1095919A external-priority patent/JPH0832722B2/ja
Priority claimed from JP1095922A external-priority patent/JPH0826070B2/ja
Priority claimed from JP1095921A external-priority patent/JPH0826069B2/ja
Priority claimed from JP1095920A external-priority patent/JPH0826067B2/ja
Application filed by Mitsuo Masaki, Masaki Uehara, Kenji Hirate, Yoshikazu Isowa, Yoshiaki Sato, Yoshiharu Nakashima, Fujirebio Kabushiki Kaisha, Nippon Chemiphar Co., Ltd. filed Critical Mitsuo Masaki
Publication of CA2014590A1 publication Critical patent/CA2014590A1/fr
Application granted granted Critical
Publication of CA2014590C publication Critical patent/CA2014590C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/16—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA002014590A 1989-04-15 1990-04-12 Peptides et agents contre la demence les contenant Expired - Fee Related CA2014590C (fr)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
JP1-95920 1989-04-15
JP1095918A JP2542254B2 (ja) 1989-04-15 1989-04-15 ペプチドおよびこれを含有する抗痴呆剤
JP1-95918 1989-04-15
JP1-95919 1989-04-15
JP1095917A JP2640778B2 (ja) 1989-04-15 1989-04-15 ペプチドおよびこれを含有する抗痴呆剤
JP1-95917 1989-04-15
JP1095919A JPH0832722B2 (ja) 1989-04-15 1989-04-15 ペプチドおよびこれを含有する抗痴呆剤
JP1-95922 1989-04-15
JP1095922A JPH0826070B2 (ja) 1989-04-15 1989-04-15 ペプチドおよびこれを含有する抗痴呆剤
JP1095921A JPH0826069B2 (ja) 1989-04-15 1989-04-15 ペプチドおよびこれを含有する抗痴呆剤
JP1-95921 1989-04-15
JP1095920A JPH0826067B2 (ja) 1989-04-15 1989-04-15 ペプチド誘導体、およびこれを含有する抗痴呆剤

Publications (2)

Publication Number Publication Date
CA2014590A1 true CA2014590A1 (fr) 1990-10-15
CA2014590C CA2014590C (fr) 1999-12-14

Family

ID=27551968

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002014590A Expired - Fee Related CA2014590C (fr) 1989-04-15 1990-04-12 Peptides et agents contre la demence les contenant

Country Status (8)

Country Link
US (2) US5112947A (fr)
EP (2) EP0620230A1 (fr)
KR (2) KR0155559B1 (fr)
AT (1) ATE113606T1 (fr)
AU (1) AU642644B2 (fr)
CA (1) CA2014590C (fr)
DE (1) DE69013742T2 (fr)
DK (1) DK0393934T3 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2014590C (fr) * 1989-04-15 1999-12-14 Mitsuo Masaki Peptides et agents contre la demence les contenant
CN1036010C (zh) * 1992-08-08 1997-10-01 中国科学院上海生物化学研究所 记忆增强肽及其应用
GB2269821B (en) * 1992-08-08 1996-06-05 Shanghai Inst Biochemistry Memory enhancing peptides and pharmaceutical compositions containing them
US6589937B1 (en) 1996-04-15 2003-07-08 Kabushiki Kaisha Yakult Honsha Peptides and nootropic agent
JP2001072602A (ja) * 1999-09-09 2001-03-21 Nippon Chemiphar Co Ltd 神経疾患治療剤
CN1154656C (zh) * 2000-06-30 2004-06-23 上海中科英泰生物技术有限公司 一类记忆增强肽和它们的用途
US9428845B1 (en) 2010-12-28 2016-08-30 Warp Drive Bio, Inc. Identifying new therapeutic agents
EP3247378B8 (fr) 2015-01-09 2023-08-23 Revolution Medicines, Inc. Composés macrocycliques participant à une liaison coopérative et leurs utilisations médicales
JP7411326B2 (ja) * 2015-10-01 2024-01-11 ワープ ドライブ バイオ インコーポレイテッド タンパク質－タンパク質インターフェースを分析するための方法および試薬
ES2921056T3 (es) 2016-04-12 2022-08-17 Warp Drive Bio Inc Composiciones y métodos para la producción de compuestos
CA3042231A1 (fr) 2016-10-28 2018-05-03 Ginkgo Bioworks, Inc. Compositions et procedes pour la production de composes
MX2022005359A (es) 2019-11-04 2022-06-02 Revolution Medicines Inc Inhibidores de ras.
AU2020379731A1 (en) 2019-11-04 2022-05-05 Revolution Medicines, Inc. Ras inhibitors
EP4055028A1 (fr) 2019-11-04 2022-09-14 Revolution Medicines, Inc. Inhibiteurs de ras
KR20230067635A (ko) 2020-09-15 2023-05-16 레볼루션 메디슨즈, 인크. 암의 치료에서 ras 억제제로서 인돌 유도체

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56021B1 (en) * 1982-10-13 1991-03-27 Akzo Nv Peptides
ATE20072T1 (de) * 1982-12-21 1986-06-15 Ferring Ab Vasotocinderivate.
IE58407B1 (en) * 1984-04-13 1993-09-22 Akzo Nv Peptides
US4748154A (en) * 1985-12-24 1988-05-31 Takeda Chemical Industries, Ltd. Peptide derivatives, their production and use
JPH0253734A (ja) * 1988-08-12 1990-02-22 Nippon Chemiphar Co Ltd 抗痴呆剤
KR0141693B1 (ko) * 1988-08-12 1998-06-15 나까무라 하루후미 펩티드 유도체 및 항치매제
KR0144005B1 (ko) * 1988-08-12 1998-07-01 나까무라 하루후미 펩티드 및 항치매제
CA2014590C (fr) * 1989-04-15 1999-12-14 Mitsuo Masaki Peptides et agents contre la demence les contenant

Also Published As

Publication number Publication date
EP0393934B1 (fr) 1994-11-02
DK0393934T3 (da) 1994-11-21
CA2014590C (fr) 1999-12-14
AU642644B2 (en) 1993-10-28
EP0620230A1 (fr) 1994-10-19
DE69013742T2 (de) 1995-03-23
KR0155559B1 (ko) 1998-10-15
US5112947A (en) 1992-05-12
DE69013742D1 (de) 1994-12-08
US5349050A (en) 1994-09-20
KR0161652B1 (ko) 1999-10-01
ATE113606T1 (de) 1994-11-15
AU5362190A (en) 1990-10-18
KR900016259A (ko) 1990-11-13
EP0393934A1 (fr) 1990-10-24

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