CA1341435C - Virus recombinant, du type variole/varicelle/vaccine, servant a immuniser contre des antigenes tumoraux - Google Patents

Virus recombinant, du type variole/varicelle/vaccine, servant a immuniser contre des antigenes tumoraux Download PDF

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Publication number
CA1341435C
CA1341435C CA000577071A CA577071A CA1341435C CA 1341435 C CA1341435 C CA 1341435C CA 000577071 A CA000577071 A CA 000577071A CA 577071 A CA577071 A CA 577071A CA 1341435 C CA1341435 C CA 1341435C
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Canada
Prior art keywords
oncogene
virus
tumor
proto
pox
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Expired - Lifetime
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CA000577071A
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English (en)
Inventor
Dennis L. Panicali
Rene Bernards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Ltd
US Department of Health and Human Services
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Whitehead Institute for Biomedical Research
Applied Bio Technology Inc
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Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
CA000577071A 1987-09-02 1988-09-02 Virus recombinant, du type variole/varicelle/vaccine, servant a immuniser contre des antigenes tumoraux Expired - Lifetime CA1341435C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9203687A 1987-09-02 1987-09-02
US092,036 1987-09-02

Publications (1)

Publication Number Publication Date
CA1341435C true CA1341435C (fr) 2003-07-29

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ID=22231039

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000577071A Expired - Lifetime CA1341435C (fr) 1987-09-02 1988-09-02 Virus recombinant, du type variole/varicelle/vaccine, servant a immuniser contre des antigenes tumoraux

Country Status (2)

Country Link
CA (1) CA1341435C (fr)
WO (1) WO1989001973A2 (fr)

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CA3091502A1 (fr) 2018-02-23 2019-08-29 Eucure (Beijing) Biopharma Co., Ltd Anticorps anti-pd-1 et leurs utilisations
US11572381B2 (en) 2018-03-02 2023-02-07 The University Of Montana Immunogenic trehalose compounds and uses thereof
CA3105875A1 (fr) 2018-07-20 2020-01-23 Eucure (Beijing) Biopharma Co., Ltd Anticorps anti-cd40 et leurs utilisations
JP7387743B2 (ja) 2018-09-12 2023-11-28 ユーカー(ベンジン) バイオファーマ カンパニー,リミテッド 抗tnfrsf9抗体及びその使用
EP3883969A4 (fr) 2018-11-19 2022-11-16 Biocytogen Pharmaceuticals (Beijing) Co., Ltd. Anticorps anti-pd-1 et leurs utilisations
JP2022521358A (ja) 2019-02-18 2022-04-06 バイオサイトジェン ファーマシューティカルズ (ベイジン) カンパニー リミテッド ヒト化免疫グロブリン遺伝子座を有する遺伝子改変非ヒト動物
AU2020278777A1 (en) 2019-05-23 2021-12-16 The University Of Montana Vaccine adjuvants based on TLR receptor ligands
KR20230018439A (ko) 2020-06-02 2023-02-07 바이오사이토젠 파마슈티컬스 (베이징) 컴퍼니 리미티드 공동 경쇄 면역글로불린 좌위를 갖는 유전자 변형 비인간 동물

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