CA1308516C - Agents antiviraux et anticancereux oligopeptidiques - Google Patents

Agents antiviraux et anticancereux oligopeptidiques

Info

Publication number
CA1308516C
CA1308516C CA000541352A CA541352A CA1308516C CA 1308516 C CA1308516 C CA 1308516C CA 000541352 A CA000541352 A CA 000541352A CA 541352 A CA541352 A CA 541352A CA 1308516 C CA1308516 C CA 1308516C
Authority
CA
Canada
Prior art keywords
compound
het
formula
equals
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000541352A
Other languages
English (en)
Inventor
J. William Lown
Krzysztof Krowicki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Alberta
Original Assignee
University of Alberta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Alberta filed Critical University of Alberta
Priority to CA000541352A priority Critical patent/CA1308516C/fr
Priority to US07/073,725 priority patent/US4912199A/en
Application granted granted Critical
Publication of CA1308516C publication Critical patent/CA1308516C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000541352A 1987-07-06 1987-07-06 Agents antiviraux et anticancereux oligopeptidiques Expired - Lifetime CA1308516C (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA000541352A CA1308516C (fr) 1987-07-06 1987-07-06 Agents antiviraux et anticancereux oligopeptidiques
US07/073,725 US4912199A (en) 1987-07-06 1987-07-15 Oligopeptide anticancer and antiviral agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA000541352A CA1308516C (fr) 1987-07-06 1987-07-06 Agents antiviraux et anticancereux oligopeptidiques
US07/073,725 US4912199A (en) 1987-07-06 1987-07-15 Oligopeptide anticancer and antiviral agents

Publications (1)

Publication Number Publication Date
CA1308516C true CA1308516C (fr) 1992-10-06

Family

ID=25671405

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000541352A Expired - Lifetime CA1308516C (fr) 1987-07-06 1987-07-06 Agents antiviraux et anticancereux oligopeptidiques

Country Status (2)

Country Link
US (1) US4912199A (fr)
CA (1) CA1308516C (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9000644D0 (en) * 1990-01-11 1990-03-14 Erba Carlo Spa New ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds
WO1992013838A1 (fr) * 1991-02-06 1992-08-20 Synphar Laboratories, Inc. Agents antiretroviraux oligopeptidiques
IT1247878B (it) * 1991-02-15 1995-01-05 Menarini Farma Ind Derivati poli-4-aminopirrol-2-carbossiamidici,processi di preparazione e composizioni farmaceutiche che li contengono
GB2261661A (en) * 1991-11-21 1993-05-26 Erba Carlo Spa Derivatives of poly-4-amino-2-carboxy-1-methyl pyrroles
US5273991A (en) * 1992-07-29 1993-12-28 Research Corporation Technologies, Inc. Imidazole-containing compositions and methods of use thereof analogs of distamycin
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
GB9304589D0 (en) * 1993-03-05 1993-04-21 Erba Carlo Spa Biologically active ureido derivatives useful as antimetastic agents
WO1995004732A1 (fr) * 1993-08-06 1995-02-16 Synphar Laboratories, Inc. Agents antiretroviraux oligopeptidiques
GB9403909D0 (en) * 1994-03-01 1994-04-20 Erba Carlo Spa Ureido derivatives of naphthalenephosphonic acids and process for their preparation
US5637621A (en) * 1994-11-14 1997-06-10 Nzym, Inc. Methods and compositions for treating Botrytis infections
US5629348A (en) * 1994-11-14 1997-05-13 Nzym, Inc. Methods and compositions for treating septoria infections
EP0792262A2 (fr) * 1994-11-14 1997-09-03 Nzym, Inc. Methodes et compositions pour le traitement de mycoses phytopathogenes
US5502068A (en) * 1995-01-31 1996-03-26 Synphar Laboratories, Inc. Cyclopropylpyrroloindole-oligopeptide anticancer agents
US6635417B1 (en) * 1996-07-31 2003-10-21 California Institute Of Technology Complex formation between DSDNA and oligomer of cyclic heterocycles
US6291514B1 (en) 1998-02-09 2001-09-18 3-Dimensional Pharmaceuticals, Inc. Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors
US6555693B2 (en) 2000-03-16 2003-04-29 Genesoft, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
US7078536B2 (en) * 2001-03-14 2006-07-18 Genesoft Pharmaceuticals, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
KR20030011371A (ko) * 2000-06-27 2003-02-07 진랩스 테크놀러지스, 인크. 항세균, 항진균 또는 항암 활성을 갖는 신규 화합물
US7122626B2 (en) * 2001-04-26 2006-10-17 Genesoft Pharmceuticals, Inc. Halogen-substitued thienyl compounds
ITTO20010633A1 (it) * 2001-07-02 2003-01-02 Univ Ferrara Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale distamicina a.
GB0130868D0 (en) * 2001-12-24 2002-02-06 Univ Strathclyde New compounds
US7064218B2 (en) * 2001-12-26 2006-06-20 Genelabs Technologies, Inc. Aromatic compounds and poly(oxyalkylene) containing aromatic compounds possessing antibacterial, antifungal or antitumor activity
DE60326735D1 (de) 2002-08-02 2009-04-30 Genesoft Pharmaceuticals Inc Biaryl-verbindungen mit antiinfektiver wirkung
US7265129B2 (en) * 2002-10-25 2007-09-04 Genesoft Pharmaceuticals, Inc. Anti-infective biaryl compounds
JP2006509027A (ja) 2002-12-10 2006-03-16 オーシェント ファーマシューティカルズ コーポレーション （ピロールカルボキサミド）−（ベンズアミド）−（イミダゾールカルボキサミド）モチーフを有する抗菌化合物
US6828526B1 (en) * 2003-05-15 2004-12-07 Alcoa Inc. Gas metal buried arc welding of lap-penetration joints
TW200819540A (en) 2006-07-11 2008-05-01 Genelux Corp Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders
GB0619325D0 (en) * 2006-09-30 2006-11-08 Univ Strathclyde New compounds
EP2426142A3 (fr) 2006-10-16 2012-06-13 Genelux Corporation Souches de virus de vaccin modifiées pour une utilisation pour le diagnostic et procédé thérapeutique
WO2008156655A2 (fr) * 2007-06-15 2008-12-24 Genelux Corporation Microorganismes pour une imagerie et/ou un traitement de tumeurs
WO2009126189A1 (fr) * 2008-01-11 2009-10-15 Genelux Corporation Procédés et compositions pour la détection de bactéries et le traitement de maladies et de troubles
CN114262690A (zh) 2011-04-15 2022-04-01 吉恩勒克斯公司 减毒的痘苗病毒的克隆毒株及其使用方法
WO2013138522A2 (fr) 2012-03-16 2013-09-19 Genelux Corporation Méthodes d'évaluation de l'efficacité et de la surveillance d'un traitement viral oncolytique
WO2013158265A1 (fr) 2012-04-20 2013-10-24 Genelux Corporation Méthodes d'imagerie pour virothérapie oncolytique
WO2014055960A1 (fr) 2012-10-05 2014-04-10 Genelux Corporation Procédés diagnostiques et thérapeutiques basés sur l'absorption d'énergie utilisant des molécules d'acide nucléique codant pour des enzymes productrices de chromophore
CN104845967B (zh) 2015-04-15 2020-12-11 苏州新海生物科技股份有限公司 寡聚核苷酸片段及使用其的选择性扩增目标核酸序列变异体的方法及应用
WO2018047148A1 (fr) 2016-09-12 2018-03-15 Novartis Ag Composés pour inhibition du miarn

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4216208A (en) * 1978-07-31 1980-08-05 Proter S.P.A. N-Acyl derivatives of glucosamines having antitumor chemotherapeutic activity
US4540683A (en) * 1978-07-31 1985-09-10 Proter S.P.A. In vitro and in vivo treatment of cancer cells and treatment of viruses with a tripeptide compound
US4314999A (en) * 1978-07-31 1982-02-09 Proter S.P.A. N-Acyl derivatives of glucosamine having antitumor chemotherapeutic acitivity
US4483850A (en) * 1982-05-10 1984-11-20 Merck & Co., Inc. N-Terminal substituted oligopeptide converting enzyme inhibitors
US4454065A (en) * 1982-05-18 1984-06-12 Smithkline Beckman Corporation Oligopeptide prodrugs
ATE171185T1 (de) * 1985-03-15 1998-10-15 Antivirals Inc Immunotestmittel für polynukleotid und verfahren

Also Published As

Publication number Publication date
US4912199A (en) 1990-03-27

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