CA1132537A - Procede de preparation de nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique - Google Patents

Procede de preparation de nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique

Info

Publication number
CA1132537A
CA1132537A CA297,248A CA297248A CA1132537A CA 1132537 A CA1132537 A CA 1132537A CA 297248 A CA297248 A CA 297248A CA 1132537 A CA1132537 A CA 1132537A
Authority
CA
Canada
Prior art keywords
formula
acid
product
products
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA297,248A
Other languages
English (en)
French (fr)
Inventor
Rene Heymes
Andre Lutz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of CA1132537A publication Critical patent/CA1132537A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA297,248A 1977-02-18 1978-02-17 Procede de preparation de nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique Expired CA1132537A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7704745 1977-02-18
FR7704745A FR2381053A1 (fr) 1977-02-18 1977-02-18 Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
CA1132537A true CA1132537A (fr) 1982-09-28

Family

ID=9186946

Family Applications (1)

Application Number Title Priority Date Filing Date
CA297,248A Expired CA1132537A (fr) 1977-02-18 1978-02-17 Procede de preparation de nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique

Country Status (23)

Country Link
JP (1) JPS53108996A (ja)
AT (1) AT355722B (ja)
AU (1) AU516076B2 (ja)
BE (1) BE864074A (ja)
CA (1) CA1132537A (ja)
CH (1) CH633016A5 (ja)
DE (1) DE2806226A1 (ja)
DK (1) DK68978A (ja)
ES (2) ES467090A1 (ja)
FI (1) FI69468C (ja)
FR (1) FR2381053A1 (ja)
GB (1) GB1575180A (ja)
GR (1) GR71703B (ja)
HU (1) HU181961B (ja)
IE (1) IE46651B1 (ja)
IL (1) IL54043A (ja)
LU (1) LU79080A1 (ja)
NL (1) NL7801834A (ja)
PT (1) PT67673B (ja)
SE (1) SE434268B (ja)
SU (1) SU841590A3 (ja)
YU (1) YU41583B (ja)
ZA (1) ZA78847B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
BE878433A (fr) * 1978-08-31 1980-02-25 Fujisawa Pharmaceutical Co Procede de preparation de derives d'acide 3-cephem-4-carboxylique 3,7-disubstitue, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
US4399132A (en) * 1980-08-11 1983-08-16 American Cyanamid Company 7-Beta-[alpha-syn-methoxyimino-alpha-(2-aminothiazol-4-yl)-acetamido]-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-3-cephem-4-carboxylic acid and C1 -C6 alkyl derivatives thereof
US4761409A (en) * 1984-08-16 1988-08-02 Sumitomo Pharmaceuticals Company, Limited Cephem derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins

Also Published As

Publication number Publication date
JPS53108996A (en) 1978-09-22
ZA78847B (en) 1979-03-28
SU841590A3 (ru) 1981-06-23
FR2381053B1 (ja) 1979-06-01
PT67673B (fr) 1980-03-03
ES475956A1 (es) 1979-12-16
IL54043A (en) 1983-02-23
BE864074A (fr) 1978-08-17
DE2806226A1 (de) 1978-08-24
IL54043A0 (en) 1978-04-30
NL7801834A (nl) 1978-08-22
ES467090A1 (es) 1979-06-01
AU3337578A (en) 1979-08-23
FI780444A (fi) 1978-08-19
IE780364L (en) 1978-08-18
FI69468B (fi) 1985-10-31
GR71703B (ja) 1983-06-21
AU516076B2 (en) 1981-05-14
SE7800790L (sv) 1978-08-18
LU79080A1 (fr) 1978-09-28
YU33678A (en) 1983-01-21
PT67673A (fr) 1978-03-01
ATA120978A (de) 1979-08-15
FR2381053A1 (fr) 1978-09-15
CH633016A5 (en) 1982-11-15
IE46651B1 (en) 1983-08-10
DK68978A (da) 1978-08-19
HU181961B (en) 1983-11-28
YU41583B (en) 1987-10-31
AT355722B (de) 1980-03-25
FI69468C (fi) 1986-02-10
SE434268B (sv) 1984-07-16
GB1575180A (en) 1980-09-17

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