CA1114808A - Derivatives of 7-¬substituted oxyiminoacetamido| cephalosporins - Google Patents

Derivatives of 7-¬substituted oxyiminoacetamido| cephalosporins

Info

Publication number
CA1114808A
CA1114808A CA304,644A CA304644A CA1114808A CA 1114808 A CA1114808 A CA 1114808A CA 304644 A CA304644 A CA 304644A CA 1114808 A CA1114808 A CA 1114808A
Authority
CA
Canada
Prior art keywords
formula
methyl
group
salts
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA304,644A
Other languages
English (en)
French (fr)
Inventor
Marc Montavon
Roland Reiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1114808A publication Critical patent/CA1114808A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CA304,644A 1977-06-03 1978-06-02 Derivatives of 7-¬substituted oxyiminoacetamido| cephalosporins Expired CA1114808A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
LU77485 1977-06-03
LU77485 1977-06-03
CH314278 1978-03-22
CH3142/78 1978-03-22

Publications (1)

Publication Number Publication Date
CA1114808A true CA1114808A (en) 1981-12-22

Family

ID=25692293

Family Applications (1)

Application Number Title Priority Date Filing Date
CA304,644A Expired CA1114808A (en) 1977-06-03 1978-06-02 Derivatives of 7-¬substituted oxyiminoacetamido| cephalosporins

Country Status (26)

Country Link
EP (1) EP0000005B1 (xx)
JP (1) JPS5412394A (xx)
AR (1) AR225134A1 (xx)
AT (2) AT362501B (xx)
AU (1) AU518648B2 (xx)
BR (1) BR7803565A (xx)
CA (1) CA1114808A (xx)
CU (1) CU21118A (xx)
DE (2) DE2824065A1 (xx)
DK (1) DK246878A (xx)
ES (2) ES470442A1 (xx)
FI (1) FI781754A (xx)
FR (1) FR2393000A1 (xx)
GB (1) GB1599232A (xx)
GR (1) GR73554B (xx)
HU (1) HU182498B (xx)
IE (1) IE46903B1 (xx)
IL (1) IL54803A (xx)
IT (1) IT1098306B (xx)
MC (1) MC1195A1 (xx)
NL (1) NL7805715A (xx)
NO (1) NO781934L (xx)
NZ (1) NZ187392A (xx)
PH (1) PH14653A (xx)
PT (1) PT68134A (xx)
SE (1) SE7806465L (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200745A (en) * 1977-12-20 1980-04-29 Eli Lilly And Company 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins
FR2432521A1 (fr) * 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
MC1259A1 (fr) * 1978-05-30 1980-01-14 Hoffmann La Roche Derives acyles
FI782683A (fi) * 1978-07-19 1980-01-20 Hoffmann La Roche Kefalosporinestrar och -estrar
US4472574A (en) * 1981-05-22 1984-09-18 Hoffman-La Roche Inc. Process for the manufacture of a cephem carboxylic acid derivative
US4698338A (en) * 1986-02-19 1987-10-06 Eli Lilly And Company 7[2-(2-aminothiazol-4-yl)-2-benzyloximino]acetamido-3[4-alkyl-5-oxo-6-hydroxy-3,4-dihydro-1,2,4-triazin-3-yl]thiomethyl cephalosporins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
CH609989A5 (en) * 1974-06-21 1979-03-30 Hoffmann La Roche Process for the preparation of acyl derivatives
CA1100129A (en) * 1974-08-02 1981-04-28 William H.W. Lunn Cephalosporin compounds
GB1555471A (en) * 1975-06-19 1979-11-14 Glaxo Lab Ltd 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
GB1596278A (en) * 1976-11-30 1981-08-26 Glaxo Operations Ltd 7-(-oxyimino-acetamino)cephalosporin derivatives

Also Published As

Publication number Publication date
HU182498B (en) 1984-01-30
IT7824165A0 (it) 1978-06-02
NZ187392A (en) 1984-05-31
DE2860248D1 (en) 1981-01-29
AT362501B (de) 1981-05-25
JPS5412394A (en) 1979-01-30
FR2393000A1 (fr) 1978-12-29
NL7805715A (nl) 1978-12-05
EP0000005A1 (de) 1978-12-20
GR73554B (xx) 1984-03-14
MC1195A1 (fr) 1979-02-23
AU518648B2 (en) 1981-10-15
IL54803A (en) 1982-01-31
FR2393000B1 (xx) 1982-10-29
IE46903B1 (en) 1983-11-02
ES470442A1 (es) 1979-10-01
ATA403578A (de) 1980-10-15
AR225134A1 (es) 1982-02-26
DK246878A (da) 1978-12-04
AU3658878A (en) 1979-12-06
CU21118A (es) 1983-04-06
PH14653A (en) 1981-10-14
PT68134A (en) 1978-07-01
ATA345980A (de) 1981-05-15
ES478115A1 (es) 1979-06-01
NO781934L (no) 1978-12-05
IL54803A0 (en) 1978-07-31
IT1098306B (it) 1985-09-07
SE7806465L (sv) 1978-12-04
BR7803565A (pt) 1979-02-20
GB1599232A (en) 1981-09-30
FI781754A (fi) 1978-12-04
IE781056L (en) 1978-12-03
AT365197B (de) 1981-12-28
EP0000005B1 (de) 1980-10-29
DE2824065A1 (de) 1978-12-14

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