CA1105475A - 1,2,3,4-tetrahydro-naphthalenes - Google Patents

1,2,3,4-tetrahydro-naphthalenes

Info

Publication number
CA1105475A
CA1105475A CA292,457A CA292457A CA1105475A CA 1105475 A CA1105475 A CA 1105475A CA 292457 A CA292457 A CA 292457A CA 1105475 A CA1105475 A CA 1105475A
Authority
CA
Canada
Prior art keywords
hydrogen
group
carbon atoms
alkyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA292,457A
Other languages
English (en)
French (fr)
Inventor
Janos Pless
Max-Peter Seiler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1105475A publication Critical patent/CA1105475A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA292,457A 1976-12-07 1977-12-06 1,2,3,4-tetrahydro-naphthalenes Expired CA1105475A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH15353/76 1976-12-07
CH1535376 1976-12-07
CH82/77 1977-01-05
CH8277 1977-01-05

Publications (1)

Publication Number Publication Date
CA1105475A true CA1105475A (en) 1981-07-21

Family

ID=25683446

Family Applications (1)

Application Number Title Priority Date Filing Date
CA292,457A Expired CA1105475A (en) 1976-12-07 1977-12-06 1,2,3,4-tetrahydro-naphthalenes

Country Status (17)

Country Link
JP (1) JPS5384955A (pt)
AT (1) AT366361B (pt)
CA (1) CA1105475A (pt)
DE (1) DE2752659A1 (pt)
DK (1) DK527877A (pt)
ES (1) ES464747A1 (pt)
FI (1) FI773595A (pt)
FR (1) FR2373513A1 (pt)
GB (1) GB1597140A (pt)
IE (1) IE45929B1 (pt)
IL (1) IL53533A (pt)
NL (1) NL7713364A (pt)
NZ (1) NZ185884A (pt)
PH (1) PH13932A (pt)
PT (1) PT67365B (pt)
SE (1) SE7713471L (pt)
SU (1) SU927110A3 (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1980000251A1 (en) * 1978-07-14 1980-02-21 American Hospital Supply Corp Derivatives of 2-amino-6,7-dihydroxytetrahydronaphthalene(adtn)
US4314082A (en) * 1978-07-14 1982-02-02 American Hospital Supply Corporation Derivatives of 2-amino-6,7-dihydroxytetrahydro naphthalene (ADTN)
EP0026848B1 (de) 1979-09-14 1983-05-04 Sandoz Ag Tetralinderivate, ihre Herstellung und Heilmittel, welche diese Verbindungen enthalten
EP0033789B1 (en) * 1980-01-30 1984-03-07 American Hospital Supply Corporation 2-alpha-methyl-dopaminimino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene, its salts, and a process for preparation thereof
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
AU8455082A (en) * 1981-05-11 1982-12-07 Folk Lars-Erik Arvidsson Therapeutically useful tetralin derivatives iii,processes forpreparation and pharmaceutical preparations for such compounds
US4455317A (en) * 1981-06-23 1984-06-19 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4454154A (en) * 1981-06-23 1984-06-12 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4578403A (en) * 1981-06-23 1986-03-25 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4559359A (en) * 1981-06-23 1985-12-17 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4402974A (en) 1981-06-23 1983-09-06 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
IT1218322B (it) * 1982-06-10 1990-04-12 Chiesi Farma Spa Derivati di 1,2,3,4-tetraidronaftalene,procedimento di preparazione e relative composizioni farmaceutiche
US4448990A (en) * 1982-11-16 1984-05-15 Eli Lilly And Company Hydroxyaminotetralincarboxamides
US4500545A (en) * 1982-11-16 1985-02-19 Eli Lilly And Company Hydroxyaminotetralincarboxamides
US4743618A (en) * 1983-01-03 1988-05-10 Nelson Research & Development Co. Substituted 2-aminotetralins
US4722933A (en) * 1985-12-20 1988-02-02 Nelson Research & Development Co. Substituted 2-aminotetralins
US4564628A (en) * 1983-01-03 1986-01-14 Nelson Research & Development Co. Substituted 2-aminotetralins
US5177112A (en) * 1983-01-03 1993-01-05 Whitby Research, Inc. Substituted 2-aminotetralins
US4657925A (en) * 1984-08-13 1987-04-14 Nelson Research & Development Co. Method and compositions for reducing the intraocular pressure of mammals
GB2157950B (en) * 1984-05-04 1988-11-02 Nelson Res & Dev Selective d-2 dopamine receptor agonist
CA1331191C (en) 1988-03-25 1994-08-02 Bengt Ronny Andersson Therapeutically useful tetralin derivatives
US5214156A (en) * 1988-03-25 1993-05-25 The Upjohn Company Therapeutically useful tetralin derivatives
US5225596A (en) * 1989-01-09 1993-07-06 The Upjohn Company Halo substituted aminotetralins
JP2931986B2 (ja) * 1989-02-17 1999-08-09 武田薬品工業株式会社 アラルキルアミン誘導体
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
EP0639557A1 (en) * 1991-03-07 1995-02-22 Zeria Pharmaceutical Co., Ltd. Trialkylamine derivative and ameliorant for digestive tract movement containing the same
CZ370198A3 (cs) * 1996-05-31 1999-05-12 Pharmacia & Upjohn Company Aryl substituované cyklické aminy jako selektivní dopaminové D3 ligandy
IT1294931B1 (it) 1997-09-22 1999-04-23 Sigma Tau Ind Farmaceuti Derivati della 2-amminotetralina procedimento per la loro preparazione e composizioni farmaceutiche che li contengono, attive nella
AR054363A1 (es) * 2005-05-23 2007-06-20 Astrazeneca Ab Compuestos que exhiben actividad moduladora en el receptor 5-hidroxi-triptamina 6
US8809590B2 (en) * 2011-06-27 2014-08-19 Shan Dong Luye Pharmaceutical Co., Ltd. Method for industrially preparing nitrogen substituted amino-5,6,7,8-tetrahydronaphthol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1017359A (en) * 1972-07-03 1977-09-13 Frederic P. Hauck Substituted cyclic polymethylene phenols

Also Published As

Publication number Publication date
NL7713364A (nl) 1978-06-09
AT366361B (de) 1982-04-13
JPS6214540B2 (pt) 1987-04-02
NZ185884A (en) 1980-04-28
ES464747A1 (es) 1979-01-01
FR2373513B1 (pt) 1980-08-22
IL53533A0 (en) 1978-03-10
IE45929B1 (en) 1982-12-29
DK527877A (da) 1978-06-08
PT67365B (fr) 1979-09-20
FR2373513A1 (fr) 1978-07-07
PT67365A (fr) 1978-01-01
SU927110A3 (ru) 1982-05-07
PH13932A (en) 1980-11-04
FI773595A (fi) 1978-06-08
JPS5384955A (en) 1978-07-26
SE7713471L (sv) 1978-06-08
DE2752659A1 (de) 1978-06-08
IE45929L (en) 1978-06-07
IL53533A (en) 1982-07-30
GB1597140A (en) 1981-09-03
ATA871977A (de) 1981-08-15

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Legal Events

Date Code Title Description
MKEX Expiry