CA1066710A - 7-methoxy-6-thiatetracyclines and their preparation - Google Patents

7-methoxy-6-thiatetracyclines and their preparation

Info

Publication number
CA1066710A
CA1066710A CA232,694A CA232694A CA1066710A CA 1066710 A CA1066710 A CA 1066710A CA 232694 A CA232694 A CA 232694A CA 1066710 A CA1066710 A CA 1066710A
Authority
CA
Canada
Prior art keywords
methoxy
acid
thiatetracycline
carbon atoms
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA232,694A
Other languages
English (en)
French (fr)
Inventor
Rudolf Gottschlich
Rolf Bergmann
Walter Hameister
Werner Rogalski
Richard Kirchlechner
Juergen Seubert
Helmut Wahlig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of CA1066710A publication Critical patent/CA1066710A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA232,694A 1974-08-03 1975-08-01 7-methoxy-6-thiatetracyclines and their preparation Expired CA1066710A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2437487A DE2437487A1 (de) 1974-08-03 1974-08-03 7-methoxy-6-thia-tetracycline und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
CA1066710A true CA1066710A (en) 1979-11-20

Family

ID=5922377

Family Applications (1)

Application Number Title Priority Date Filing Date
CA232,694A Expired CA1066710A (en) 1974-08-03 1975-08-01 7-methoxy-6-thiatetracyclines and their preparation

Country Status (20)

Country Link
US (1) US3988468A (nl)
JP (1) JPS5141362A (nl)
AT (1) AT344889B (nl)
BE (1) BE832015A (nl)
CA (1) CA1066710A (nl)
CS (1) CS191882B2 (nl)
DD (1) DD119426A5 (nl)
DE (1) DE2437487A1 (nl)
DK (1) DK135842C (nl)
ES (1) ES439927A1 (nl)
FR (1) FR2280386A1 (nl)
GB (1) GB1464678A (nl)
HU (1) HU171804B (nl)
IE (1) IE41440B1 (nl)
IL (1) IL47535A (nl)
LU (1) LU73113A1 (nl)
NL (1) NL7509205A (nl)
PL (1) PL100508B1 (nl)
SE (1) SE7508642L (nl)
ZA (1) ZA754975B (nl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2442829A1 (de) * 1974-09-06 1976-03-18 Merck Patent Gmbh Tetracyclische verbindungen und verfahren zu ihrer herstellung
DE2746044C2 (de) * 1977-10-13 1979-09-06 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur Herstellung von e-Thiatetracyclinracematen mit natürlicher Konfiguration und ihren optischen Antipoden
JPS5845093A (ja) * 1981-09-11 1983-03-16 Kobe Steel Ltd 平版用印刷基板
JPS60196396A (ja) * 1984-03-21 1985-10-04 Ube Ind Ltd 平版印刷板用基材
US6818635B2 (en) * 2000-07-07 2004-11-16 Paratek Pharmaceuticals, Inc. 7-substituted tetracycline compounds
JP2005506291A (ja) * 2001-03-13 2005-03-03 パラテック ファーマシューティカルズ， インク． ７，９−置換テトラサイクリン化合物
WO2004006850A2 (en) 2002-07-12 2004-01-22 Paratek Pharmaceuticals, Inc 3, 10, AND 12a SUBSTITUTED TETRACYCLINE COMPOUNDS
AU2005299294B2 (en) * 2004-10-25 2012-06-07 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
CN107021887A (zh) 2009-05-08 2017-08-08 四相制药公司 四环素类化合物
PL2470500T3 (pl) * 2009-08-28 2018-03-30 Tetraphase Pharmaceuticals, Inc. Związki tetracyklinowe
NZ740051A (en) 2012-08-31 2019-09-27 Tetraphase Pharmaceuticals Inc Tetracycline compounds
MA46567A (fr) 2016-10-19 2019-08-28 Tetraphase Pharmaceuticals Inc Formes cristallines de l'éravacycline
CN109574868B (zh) * 2018-12-28 2021-11-16 天津阿尔塔科技有限公司 一种四环素类及其差向异构体氘代内标物的制备方法
CN111518115A (zh) * 2020-04-15 2020-08-11 南京欧纳壹有机光电有限公司 硫醚取代的2-噻唑啉-4-酮封端的有机半导体化合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL158172B (nl) * 1972-09-18 1978-10-16 Farmaceutici Italia Werkwijze voor het bereiden van tetracyclinederivaten met een substituent op de 7-plaats.

Also Published As

Publication number Publication date
GB1464678A (en) 1977-02-16
DK351875A (da) 1976-02-04
AU8360175A (en) 1977-02-03
IL47535A (en) 1978-04-30
CS191882B2 (en) 1979-07-31
DK135842C (da) 1977-11-28
FR2280386A1 (fr) 1976-02-27
LU73113A1 (nl) 1976-03-02
US3988468A (en) 1976-10-26
BE832015A (nl) 1976-02-02
DK135842B (da) 1977-07-04
PL100508B1 (pl) 1978-10-31
IE41440B1 (en) 1980-01-02
NL7509205A (nl) 1976-02-05
JPS5141362A (en) 1976-04-07
HU171804B (hu) 1978-03-28
ATA600375A (de) 1977-12-15
DE2437487A1 (de) 1976-02-19
IL47535A0 (en) 1975-08-31
IE41440L (en) 1976-02-03
FR2280386B1 (nl) 1979-10-12
SE7508642L (sv) 1976-02-04
ES439927A1 (es) 1977-06-01
AT344889B (de) 1978-08-10
DD119426A5 (nl) 1976-04-20
ZA754975B (en) 1976-07-28

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