CA1035353A - 3-thiolated-7-acylamidocephalosporanic acids - Google Patents

3-thiolated-7-acylamidocephalosporanic acids

Info

Publication number
CA1035353A
CA1035353A CA191,467A CA191467A CA1035353A CA 1035353 A CA1035353 A CA 1035353A CA 191467 A CA191467 A CA 191467A CA 1035353 A CA1035353 A CA 1035353A
Authority
CA
Canada
Prior art keywords
thiolated
acylamidocephalosporanic
acids
acylamidocephalosporanic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA191,467A
Other languages
French (fr)
Inventor
Lee C. Cheney
Charles T. Holdrege
Stephen R. Baker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of CA1035353A publication Critical patent/CA1035353A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/121,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/061,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/121,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/1251,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896Compounds having one or more Si-O-acyl linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA191,467A 1973-01-31 1974-01-31 3-thiolated-7-acylamidocephalosporanic acids Expired CA1035353A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32823473A 1973-01-31 1973-01-31
US36169673A 1973-05-18 1973-05-18

Publications (1)

Publication Number Publication Date
CA1035353A true CA1035353A (en) 1978-07-25

Family

ID=26986279

Family Applications (1)

Application Number Title Priority Date Filing Date
CA191,467A Expired CA1035353A (en) 1973-01-31 1974-01-31 3-thiolated-7-acylamidocephalosporanic acids

Country Status (7)

Country Link
JP (1) JPS5953275B2 (en)
CA (1) CA1035353A (en)
DE (1) DE2404592C2 (en)
FR (2) FR2215942B1 (en)
GB (1) GB1439419A (en)
NL (1) NL7401361A (en)
PH (2) PH16419A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL49183A0 (en) * 1975-03-27 1976-05-31 Pfizer Novel cephalosporin derivatives,their preparation and pharmaceutical compositions containing them

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6915169D0 (en) * 1969-04-21 1973-02-20 Bristol Myers Co CHEMICAL PROCESS
NL7112483A (en) * 1970-09-14 1972-03-16
IL38099A (en) * 1970-12-17 1976-01-30 Smith Kline French Lab 3-heterocyclyl thiomethylcephalosporins
NL7200588A (en) * 1971-01-18 1972-07-20
US3757014A (en) * 1971-05-07 1973-09-04 Bristol Myers Co Ts 1,3,4 - oxadiazol-2-yl)thiomethyl)-3-cephem-4-carboxylic acid and sal7-(d-(alpha-amino-alpha-pheyle-acetamido)) - 3-(s-(5-hydroxymethyl -
CA999574A (en) * 1972-06-14 1976-11-09 Smith Kline And French Canada Ltd. 7-hydroxyhalophenylacetamido-3-h heterocyclicthiomethyl cephalosporins
CA1076560A (en) * 1972-06-14 1980-04-29 Smith Kline And French Canada Ltd. 3-heterocyclic thiomethylcephalosporins

Also Published As

Publication number Publication date
GB1439419A (en) 1976-06-16
DE2404592A1 (en) 1974-08-01
JPS49101395A (en) 1974-09-25
FR2215942B1 (en) 1978-12-22
FR2215942A1 (en) 1974-08-30
FR2391728A1 (en) 1978-12-22
NL7401361A (en) 1974-08-02
FR2391728B1 (en) 1982-08-20
DE2404592C2 (en) 1984-01-19
PH16419A (en) 1983-09-29
PH14842A (en) 1981-12-16
JPS5953275B2 (en) 1984-12-24

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