CA1030972A - Pharmacologically active benzo (b) thiophene compounds and process for their preparation - Google Patents
Pharmacologically active benzo (b) thiophene compounds and process for their preparationInfo
- Publication number
- CA1030972A CA1030972A CA228,687A CA228687A CA1030972A CA 1030972 A CA1030972 A CA 1030972A CA 228687 A CA228687 A CA 228687A CA 1030972 A CA1030972 A CA 1030972A
- Authority
- CA
- Canada
- Prior art keywords
- preparation
- pharmacologically active
- thiophene compounds
- active benzo
- benzo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2525674A GB1456323A (en) | 1974-06-06 | 1974-06-06 | Benzothiophenes process for preparing them and pharmaceutical compositions containing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1030972A true CA1030972A (en) | 1978-05-09 |
Family
ID=10224753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA228,687A Expired CA1030972A (en) | 1974-06-06 | 1975-06-06 | Pharmacologically active benzo (b) thiophene compounds and process for their preparation |
Country Status (20)
Country | Link |
---|---|
US (1) | US4007204A (de) |
JP (1) | JPS516958A (de) |
AR (2) | AR207152A1 (de) |
AT (1) | AT341517B (de) |
BE (1) | BE829837A (de) |
CA (1) | CA1030972A (de) |
CH (1) | CH605910A5 (de) |
DE (1) | DE2522655A1 (de) |
DK (1) | DK135808B (de) |
ES (1) | ES438303A1 (de) |
FI (1) | FI751602A (de) |
GB (1) | GB1456323A (de) |
HU (1) | HU172820B (de) |
IT (1) | IT1038094B (de) |
NL (1) | NL7504921A (de) |
NO (1) | NO751989L (de) |
OA (1) | OA05022A (de) |
SE (1) | SE7505482L (de) |
SU (1) | SU578002A3 (de) |
ZA (1) | ZA752871B (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU509682B2 (en) * | 1975-10-28 | 1980-05-22 | Eli Lilly And Company | 2-Aroyl-3-Phenylbenzothiophene Derivatives |
US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
US5175184A (en) * | 1982-10-19 | 1992-12-29 | Kotobuki Seiyaku Company Limited | Benzothiophene derivatives and antihyperuricemia thereof |
NO174506B (no) * | 1984-10-30 | 1994-02-07 | Usv Pharma Corp | Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser |
US4806663A (en) * | 1987-04-06 | 1989-02-21 | The University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzofuran derivatives |
US4851554A (en) * | 1987-04-06 | 1989-07-25 | University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzofuran derivatives |
US4912642A (en) * | 1987-09-03 | 1990-03-27 | The Boeing Company | Coordinated engine autothrottle |
US4831156A (en) * | 1987-09-30 | 1989-05-16 | The University Of Tennessee Research Corp. | 3-substituted 2-alkyl indole derivatives |
AU2543388A (en) * | 1987-09-30 | 1989-04-18 | University Of Tennessee Research Corporation, The | Certain 3-substituted 2-alkyl benzothiophene derivatives |
JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
CN1073563C (zh) * | 1994-04-11 | 2001-10-24 | 中外制药株式会社 | 4,6-二叔丁基-2,3-二氢苯并噻吩衍生物 |
CO4410191A1 (es) * | 1994-09-19 | 1997-01-09 | Lilly Co Eli | SINTESIS DE 3-[4-(2-AMINOETOXI)BENZOIL]-2-ARIL-6- HIDROXIBENZO [b] TIOFENOS |
US6653328B1 (en) * | 1995-03-10 | 2003-11-25 | Eli Lilly And Company | 3-benzyl-benzothiophenes |
US6417199B1 (en) * | 1995-03-10 | 2002-07-09 | Eli Lilly And Company | 3-benzyl-benzothiophenes |
ATE284690T1 (de) * | 1995-10-31 | 2005-01-15 | Lilly Co Eli | Antithrombotische diamine |
WO1997034888A1 (en) * | 1996-03-19 | 1997-09-25 | Eli Lilly And Company | SYNTHESIS OF 3-[4-(2-AMINOETHOXY)-BENZOYL]-2-ARYL-6-HYDROXY-BENZO[b]THIOPHENES |
US6391901B1 (en) | 1997-04-30 | 2002-05-21 | Eli Lilly And Company | Thrombin inhibitors |
WO1998048792A1 (en) * | 1997-04-30 | 1998-11-05 | Eli Lilly And Company | A REGIOSELECTIVE ALKYLATION PROCESS FOR PREPARING SUBSTITUTED BENZO[b]THIOPHENES |
ATE268768T1 (de) | 1997-04-30 | 2004-06-15 | Lilly Co Eli | Antithrombosemittel |
JP2002513415A (ja) | 1997-04-30 | 2002-05-08 | イーライ・リリー・アンド・カンパニー | 抗血栓剤 |
CA2288144A1 (en) | 1997-04-30 | 1998-11-05 | Eli Lilly And Company | Antithrombotic agents |
US6284756B1 (en) | 1998-04-30 | 2001-09-04 | Eli Lilly And Company | Antithrombotic agents |
ES2189355T3 (es) * | 1998-10-28 | 2003-07-01 | Lilly Co Eli | Compuestos de benzotiofeno como agentes antitromboticos e intermedios. |
FR2864536B1 (fr) * | 2003-12-24 | 2006-03-17 | Clariant France Sa | Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre |
MY160768A (en) * | 2010-08-06 | 2017-03-15 | Tasly Pharmaceutical Group Co | Use of salvia miltiorrhiza composition in preparing drugs for secondary prevention of coronary heart disease |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3514465A (en) * | 1966-12-30 | 1970-05-26 | Degussa | Certain thiazolyl- and pyridinylaminoketones |
US3706747A (en) * | 1970-06-05 | 1972-12-19 | Pfizer | Benzothieno(3,2-d)- and benzofuro(3,2-d)pyrimidines |
-
1974
- 1974-06-06 GB GB2525674A patent/GB1456323A/en not_active Expired
-
1975
- 1975-01-01 AR AR258913A patent/AR207152A1/es active
- 1975-04-21 US US05/569,819 patent/US4007204A/en not_active Expired - Lifetime
- 1975-04-25 NL NL7504921A patent/NL7504921A/xx not_active Application Discontinuation
- 1975-05-02 ZA ZA00752871A patent/ZA752871B/xx unknown
- 1975-05-13 SE SE7505482A patent/SE7505482L/xx unknown
- 1975-05-14 IT IT23297/75A patent/IT1038094B/it active
- 1975-05-22 DE DE19752522655 patent/DE2522655A1/de active Pending
- 1975-05-30 FI FI751602A patent/FI751602A/fi not_active Application Discontinuation
- 1975-05-30 HU HU75LA00000867A patent/HU172820B/hu unknown
- 1975-06-04 DK DK251975AA patent/DK135808B/da unknown
- 1975-06-04 BE BE157003A patent/BE829837A/xx unknown
- 1975-06-05 SU SU7502143254A patent/SU578002A3/ru active
- 1975-06-05 NO NO751989A patent/NO751989L/no unknown
- 1975-06-06 CA CA228,687A patent/CA1030972A/en not_active Expired
- 1975-06-06 CH CH730375A patent/CH605910A5/xx not_active IP Right Cessation
- 1975-06-06 OA OA55520A patent/OA05022A/xx unknown
- 1975-06-06 ES ES438303A patent/ES438303A1/es not_active Expired
- 1975-06-06 AT AT431175A patent/AT341517B/de not_active IP Right Cessation
- 1975-06-06 JP JP50069021A patent/JPS516958A/ja active Pending
- 1975-11-07 AR AR261103A patent/AR210265A1/es active
Also Published As
Publication number | Publication date |
---|---|
JPS516958A (en) | 1976-01-20 |
AR207152A1 (es) | 1976-09-15 |
OA05022A (fr) | 1980-12-31 |
CH605910A5 (de) | 1978-10-13 |
GB1456323A (en) | 1976-11-24 |
DK135808B (da) | 1977-06-27 |
DE2522655A1 (de) | 1975-12-18 |
NO751989L (de) | 1975-12-09 |
IT1038094B (it) | 1979-11-20 |
US4007204A (en) | 1977-02-08 |
FI751602A (de) | 1975-12-07 |
AT341517B (de) | 1978-02-10 |
DK135808C (de) | 1977-11-28 |
BE829837A (fr) | 1975-12-04 |
DK251975A (de) | 1975-12-07 |
HU172820B (hu) | 1978-12-28 |
ZA752871B (en) | 1976-04-28 |
ATA431175A (de) | 1977-06-15 |
SU578002A3 (ru) | 1977-10-25 |
SE7505482L (sv) | 1975-12-08 |
NL7504921A (nl) | 1975-12-09 |
AU8102275A (en) | 1976-11-11 |
AR210265A1 (es) | 1977-07-15 |
ES438303A1 (es) | 1977-01-16 |
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