BRPI1016215B8 - processo para a preparação de um comprimido de desintegração rápida - Google Patents

processo para a preparação de um comprimido de desintegração rápida

Info

Publication number
BRPI1016215B8
BRPI1016215B8 BRPI1016215A BRPI1016215A BRPI1016215B8 BR PI1016215 B8 BRPI1016215 B8 BR PI1016215B8 BR PI1016215 A BRPI1016215 A BR PI1016215A BR PI1016215 A BRPI1016215 A BR PI1016215A BR PI1016215 B8 BRPI1016215 B8 BR PI1016215B8
Authority
BR
Brazil
Prior art keywords
tablet
preparation
cavity
rapidly disintegrating
disintegrating tablet
Prior art date
Application number
BRPI1016215A
Other languages
English (en)
Inventor
Almer Middelbeek Hans
A C Smit; Jozefus
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of BRPI1016215A2 publication Critical patent/BRPI1016215A2/pt
Publication of BRPI1016215A8 publication Critical patent/BRPI1016215A8/pt
Publication of BRPI1016215B1 publication Critical patent/BRPI1016215B1/pt
Publication of BRPI1016215B8 publication Critical patent/BRPI1016215B8/pt
Publication of BRPI1016215C1 publication Critical patent/BRPI1016215C1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

processo para a preparação de um comprimido de desintegração rápida, sistema para realizar um processo, e, embalagem. a presente invenção diz respeito a um processo para a preparação de um comprimido de desintegração rápida (30) contendo uma substância médica, compreendendo as etapas de fornecer uma formulação fluida compreendendo a substância médica, fornecendo um elemento sólido (100) tendo formado no mesmo pelo menos uma cavidade, (101) resfriando o elemento sólido (100) a uma temperatura abaixo de uma temperatura de congelamento da formulação, preenchendo a cavidade com a formulação fluida, solidificando a formulação ao mesmo tempo presente na cavidade (101) para formar uma pastilha sólida compreendendo a substância médica sem ativamente modelar toda a superfície da pastilhas, retirando a pastilhas da cavidade e secando a pastilha em um vácuo para obter comprimido. a invenção também diz respeito a um sistema para realizar um processo como este e uma embalagem contendo o comprimido resultante.
BRPI1016215A 2009-04-29 2010-04-28 processo para a preparação de um comprimido de desintegração rápida BRPI1016215C1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17363109P 2009-04-29 2009-04-29
EP09159040.6 2009-04-29
US61/173,631 2009-04-29
EP09159040 2009-04-29
PCT/EP2010/055679 WO2010125084A1 (en) 2009-04-29 2010-04-28 Process to form a tablet and apparatus suitable for applying this process

Publications (5)

Publication Number Publication Date
BRPI1016215A2 BRPI1016215A2 (pt) 2016-04-26
BRPI1016215A8 BRPI1016215A8 (pt) 2018-01-02
BRPI1016215B1 BRPI1016215B1 (pt) 2021-01-05
BRPI1016215B8 true BRPI1016215B8 (pt) 2021-03-30
BRPI1016215C1 BRPI1016215C1 (pt) 2021-05-25

Family

ID=41110766

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1016215A BRPI1016215C1 (pt) 2009-04-29 2010-04-28 processo para a preparação de um comprimido de desintegração rápida

Country Status (10)

Country Link
EP (1) EP2424485B1 (pt)
JP (1) JP5620976B2 (pt)
CN (1) CN102413808B (pt)
AR (1) AR076464A1 (pt)
BR (1) BRPI1016215C1 (pt)
ES (1) ES2558852T3 (pt)
HU (1) HUE027459T2 (pt)
RU (1) RU2529785C2 (pt)
TW (1) TWI468157B (pt)
WO (1) WO2010125084A1 (pt)

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RU2567668C2 (ru) 2009-05-26 2015-11-10 Эдванст Бионутришн Корпорейшн Стабильная сухая порошкообразная композиция, содержащая биологически активные микроорганизмы и/или биоактивные материалы, и способ ее изготовления
NZ601017A (en) 2010-01-28 2014-07-25 Advanced Bionutrition Corp Dry glassy composition comprising a bioactive material
US9504750B2 (en) 2010-01-28 2016-11-29 Advanced Bionutrition Corporation Stabilizing composition for biological materials
CN103261214B (zh) 2010-12-22 2016-10-26 英特维特国际股份有限公司 具有活细菌分离物的用于全身施用的疫苗
US8192659B1 (en) * 2011-09-12 2012-06-05 On Demand Therapeutics, Inc. Methods of making microtablets for drug delivery
CA2851658C (en) 2011-10-21 2022-03-15 Intervet International B.V. Recombinant non-pathogenic marek's disease virus constructs encoding infectious laryngotracheitis virus and newcastle disease virus antigens
BR112014008161A2 (pt) 2011-10-21 2017-04-11 Intervet Int Bv vírus da doença de marek não patogênico recombinante, método para a preparação do mesmo, molécula do ácido nucleico, célula hospedeira, vacina para aves domésticas, método para a preparação de uma vacina, uso de um vírus da doença de marek não patogênico recombinante, e, método de vacinação de aves domésticas
CN102755253A (zh) * 2012-01-17 2012-10-31 海南卫康制药(潜山)有限公司 制造在相连的盛药皿包装内冷冻干燥片剂的方法
WO2013114400A2 (en) * 2012-01-20 2013-08-08 Rubicon Research Private Limited Compressed pharmaceutical compositions of atypical antipsychotics
CN114601849A (zh) * 2012-03-23 2022-06-10 先进生物营养公司 生物材料的稳定化组合物
US20140017318A1 (en) * 2012-07-10 2014-01-16 Kevin O'Connell Method to produce a medicinal product comprising a biologically active protein and the resulting product
US9314519B2 (en) 2012-08-21 2016-04-19 Intervet Inc. Liquid stable virus vaccines
JP6196677B2 (ja) 2012-10-26 2017-09-13 インターベット インターナショナル ベー． フェー． 交差防御性サルモネラワクチン
WO2014090386A1 (en) 2012-12-11 2014-06-19 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Orally disintegrating tablet containing asenapine
US9393298B2 (en) 2013-03-15 2016-07-19 Intervet Inc. Liquid stable bovine virus vaccines
US9480739B2 (en) 2013-03-15 2016-11-01 Intervet Inc. Bovine virus vaccines that are liquid stable
AR097762A1 (es) 2013-09-27 2016-04-13 Intervet Int Bv Formulaciones secas de vacunas que son estables a temperatura ambiente
AR099470A1 (es) 2014-02-17 2016-07-27 Intervet Int Bv Vacunas de virus de aves de corral líquidas
TWI670085B (zh) 2014-02-19 2019-09-01 荷蘭商英特威國際公司 液體穩定之豬病毒疫苗
WO2015162273A1 (en) 2014-04-25 2015-10-29 Merck Sharp & Dohme Bv A method to dry multiple individual frozen bodies and a system for applying this method
WO2017019273A1 (en) 2015-07-29 2017-02-02 Advanced Bionutrition Corporation Stable dry probiotic compositions for special dietary uses
CN106551804B (zh) * 2015-09-30 2022-04-26 董玲 一种使用滚模制备冻干赋形制剂的方法及其产品
US11596687B2 (en) 2016-06-17 2023-03-07 Intervet Inc. Recombinant non-pathogenic Marek's disease virus constructs encoding infectious laryngotracheitis virus and infectious bursal disease virus antigens
JP2019002652A (ja) * 2017-06-19 2019-01-10 株式会社島川製作所 真空加熱炉
BR112020007213A2 (pt) 2017-10-12 2020-10-13 Intervet International B.V. construtos de vírus da doença de marek não patogênico recombinante que codificam múltiplos antígenos heterólogos
WO2020002605A1 (en) 2018-06-29 2020-01-02 Universiteit Gent Freezing, drying and/or freeze-drying of product dose units
KR102281776B1 (ko) * 2019-09-10 2021-07-27 주식회사 제네웰 동결건조용 몰드 및 이를 사용하는 수용성 고분자 구의 제조방법
CN111888257B (zh) * 2020-08-25 2022-11-22 泉州烜之璟医疗设备有限公司 一种天麻制丸设备
RU2755154C1 (ru) * 2021-02-26 2021-09-13 Екатерина Сергеевна Стаценко Способ получения пищевой добавки на основе сои
CN113137835A (zh) * 2021-05-18 2021-07-20 甘肃省方熙药业科技有限公司 一种紫草干燥加工方法

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JP3981569B2 (ja) * 2002-02-26 2007-09-26 天野実業株式会社 乾燥装置
DE60307082T4 (de) * 2002-05-07 2015-04-30 Ferring B.V. In der mundhöhle dispergierbare phamarzeutische zusammensetzung mit desmopressin
FR2868520B1 (fr) * 2004-04-06 2006-07-07 Millennium Energy Sa Installation de deshydratation par zeolithes
US20070048369A1 (en) * 2005-08-26 2007-03-01 National Starch And Chemical Investment Holding Corporation Mucosal delivery tablet

Also Published As

Publication number Publication date
CN102413808B (zh) 2015-02-18
AR076464A1 (es) 2011-06-15
WO2010125084A1 (en) 2010-11-04
EP2424485B1 (en) 2015-11-04
JP2012525175A (ja) 2012-10-22
ES2558852T3 (es) 2016-02-09
CN102413808A (zh) 2012-04-11
BRPI1016215C1 (pt) 2021-05-25
BRPI1016215B1 (pt) 2021-01-05
RU2529785C2 (ru) 2014-09-27
BRPI1016215A8 (pt) 2018-01-02
JP5620976B2 (ja) 2014-11-05
EP2424485A1 (en) 2012-03-07
TW201103529A (en) 2011-02-01
BRPI1016215A2 (pt) 2016-04-26
HUE027459T2 (en) 2016-09-28
RU2011148341A (ru) 2013-06-10
TWI468157B (zh) 2015-01-11

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 05/01/2021, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant

Free format text: REF.RPI 2609 DE 05/01/2021 QUANTO AO ENDERECO.

B16C Correction of notification of the grant

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 28/04/2010 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B15V Prolongation of time limit allowed