BRPI1010303A2 - anestésico dental compreendendo tetracaína e um vasoconstritor para administração intranasal. - Google Patents

anestésico dental compreendendo tetracaína e um vasoconstritor para administração intranasal.

Info

Publication number
BRPI1010303A2
BRPI1010303A2 BRPI1010303A BRPI1010303A BRPI1010303A2 BR PI1010303 A2 BRPI1010303 A2 BR PI1010303A2 BR PI1010303 A BRPI1010303 A BR PI1010303A BR PI1010303 A BRPI1010303 A BR PI1010303A BR PI1010303 A2 BRPI1010303 A2 BR PI1010303A2
Authority
BR
Brazil
Prior art keywords
vasoconstrictor
tetracaine
intranasal administration
dental anesthetic
anesthetic
Prior art date
Application number
BRPI1010303A
Other languages
English (en)
Inventor
Mark David Kollar
Original Assignee
St Renatus Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Renatus Llc filed Critical St Renatus Llc
Publication of BRPI1010303A2 publication Critical patent/BRPI1010303A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/4174Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M19/00Local anaesthesia; Hypothermia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI1010303A 2009-04-03 2010-04-02 anestésico dental compreendendo tetracaína e um vasoconstritor para administração intranasal. BRPI1010303A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16668009P 2009-04-03 2009-04-03
PCT/US2010/001002 WO2010114622A1 (en) 2009-04-03 2010-04-02 Dental anesthetic comprising tetracaine and a vasoconstrictor for intranasal administration

Publications (1)

Publication Number Publication Date
BRPI1010303A2 true BRPI1010303A2 (pt) 2016-03-15

Family

ID=42164462

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1010303A BRPI1010303A2 (pt) 2009-04-03 2010-04-02 anestésico dental compreendendo tetracaína e um vasoconstritor para administração intranasal.

Country Status (18)

Country Link
US (7) US8580282B2 (pt)
EP (1) EP2413899B1 (pt)
JP (3) JP5788864B2 (pt)
KR (2) KR20170026639A (pt)
CN (2) CN102421416B (pt)
AU (2) AU2010232995C1 (pt)
BR (1) BRPI1010303A2 (pt)
CA (1) CA2757032C (pt)
DK (1) DK2413899T3 (pt)
EA (1) EA024184B1 (pt)
ES (1) ES2861064T3 (pt)
IL (1) IL215489A0 (pt)
MX (1) MX2011010445A (pt)
NZ (2) NZ595376A (pt)
PL (1) PL2413899T3 (pt)
PT (1) PT2413899T (pt)
WO (1) WO2010114622A1 (pt)
ZA (2) ZA201107011B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI1010303A2 (pt) * 2009-04-03 2016-03-15 St Renatus Llc anestésico dental compreendendo tetracaína e um vasoconstritor para administração intranasal.
AU2013323246A1 (en) 2012-09-28 2015-04-16 St. Renatus, Llc Pharmaceutical composition comprising benzyl alcohol for the treatment of migraines
EP3086785A4 (en) * 2014-01-01 2017-08-30 Real Time Imaging Technologies, LLC Improved local anesthetic solution for dental and/or contrast media use
CA2952622A1 (en) * 2014-06-16 2015-12-23 Loewi LLC Methods of anesthetizing nerve tissue in the trigeminal nerve pathway and medical uses thereof
WO2016105482A1 (en) * 2014-12-23 2016-06-30 St. Renatus, Llc Tetracaine-based anesthetic
EP3244800A1 (en) 2015-01-12 2017-11-22 Real Time Imaging Technologies, LLC Low-dose x-ray imaging system
US10039830B2 (en) * 2016-03-04 2018-08-07 Cetylite Industries, Inc. Topical anesthetic composition
WO2017210390A1 (en) * 2016-06-01 2017-12-07 St. Renatus, Llc Intranasal dental anesthetic
MX2021007213A (es) 2018-12-19 2021-09-23 Grace therapeutics Inc Composicion terapeutica de lidocaina intranasal.
CN111494310A (zh) * 2020-04-29 2020-08-07 周晓玲 一种局部***物的制备及使用方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3832460A (en) 1971-03-19 1974-08-27 C Kosti Anesthetic-vasoconstrictor-antihistamine composition for the treatment of hypertrophied oral tissue
US5209724A (en) 1988-04-11 1993-05-11 Dhaliwal Avtar S Composite anesthetic article and method of use
ATE152630T1 (de) 1992-07-28 1997-05-15 Procter & Gamble Pharmazeutische zusammensetzung zur topischen anwendung die ein vernetztes kationisches polymer und einen alkoxylierte äther enthält
US5854269A (en) 1993-11-19 1998-12-29 Schering-Plough Healthcare Products, Inc. Nasal spray compositions
US5585398A (en) 1994-07-15 1996-12-17 Ernst; Amy A. Topical anesthetic comprising lidocaine, adrenaline, and tetracaine, and its method of use
US6075059A (en) 1999-02-24 2000-06-13 The Ohio State University Compositions for dental anesthesia
US20040131665A1 (en) * 1999-10-22 2004-07-08 Wepfer Scott T. Topical anesthetic formulation
US6413499B1 (en) * 2000-01-06 2002-07-02 Bryan M. Clay Methods and kits for maxillary dental anesthesia by means of a nasal deliverable anesthetic
US20040045546A1 (en) 2002-09-05 2004-03-11 Peirce Management, Llc Pharmaceutical delivery system for oral inhalation through nebulization consisting of inert substrate impregnated with substance (S) to be solubilized or suspended prior to use
JP4591746B2 (ja) * 2002-12-03 2010-12-01 大正製薬株式会社 難溶性抗ウイルス成分含有水溶性外用剤組成物
ES2223277B1 (es) * 2003-06-19 2006-03-01 Fernando Bouffard Fita Composicion anestesica para administracion topica.
EA009669B1 (ru) 2004-01-01 2008-02-28 Панацея Биотек Лтд. Фармацевтические композиции, содержащие экстракт euphorbia prostrata
US20060052305A1 (en) * 2004-05-10 2006-03-09 Nastech Pharmaceutical Company Inc. Method of treating osteoporosis using intranasal parathyroid hormone
EP2108360A3 (en) 2005-10-24 2010-06-09 Collegium Pharmaceutical, Inc. Topical Pharmaceutical Foam Composition
US9252862B2 (en) 2008-09-17 2016-02-02 Qualcomm Incorporated MIMO preamble for initial access with an unknown number of transmit antennas
BRPI1010303A2 (pt) 2009-04-03 2016-03-15 St Renatus Llc anestésico dental compreendendo tetracaína e um vasoconstritor para administração intranasal.

Also Published As

Publication number Publication date
EP2413899A1 (en) 2012-02-08
CA2757032A1 (en) 2010-10-07
US20170326111A1 (en) 2017-11-16
CA2757032C (en) 2022-06-07
CN103932973A (zh) 2014-07-23
PT2413899T (pt) 2021-03-30
US20120039960A1 (en) 2012-02-16
US10456377B2 (en) 2019-10-29
DK2413899T3 (da) 2021-04-19
JP2017031226A (ja) 2017-02-09
ZA201107011B (en) 2014-03-26
JP2015034167A (ja) 2015-02-19
PL2413899T3 (pl) 2021-09-20
JP2012522783A (ja) 2012-09-27
NZ595376A (en) 2013-09-27
CN102421416B (zh) 2014-05-28
IL215489A0 (en) 2011-12-29
WO2010114622A1 (en) 2010-10-07
EA024184B1 (ru) 2016-08-31
KR20120042729A (ko) 2012-05-03
US20170326112A1 (en) 2017-11-16
ES2861064T3 (es) 2021-10-05
US9308191B2 (en) 2016-04-12
AU2010232995B2 (en) 2015-07-16
AU2010232995C1 (en) 2016-01-28
EP2413899B1 (en) 2021-01-27
ZA201309321B (en) 2016-07-27
US20170319547A1 (en) 2017-11-09
US9855247B2 (en) 2018-01-02
AU2015242984A1 (en) 2015-11-05
US20200268715A1 (en) 2020-08-27
US20140234421A1 (en) 2014-08-21
NZ612063A (en) 2015-02-27
EA201171215A1 (ru) 2012-07-30
MX2011010445A (es) 2012-01-19
AU2010232995A1 (en) 2011-10-20
US8580282B2 (en) 2013-11-12
KR101747979B1 (ko) 2017-06-15
US20160184269A1 (en) 2016-06-30
US10420750B2 (en) 2019-09-24
KR20170026639A (ko) 2017-03-08
CN102421416A (zh) 2012-04-18
JP5788864B2 (ja) 2015-10-07
AU2015242984B2 (en) 2017-09-14
CN103932973B (zh) 2017-08-11

Similar Documents

Publication Publication Date Title
BRPI1010303A2 (pt) anestésico dental compreendendo tetracaína e um vasoconstritor para administração intranasal.
NO2017033I2 (no) baricitinib og farmasøytisk akseptable salter derav
BR112012004178A2 (pt) implemento para cuidado oral, e, aparelho para um implemento oral
BRPI0822722A2 (pt) Implemento para cuidado oral.
DK3323462T3 (da) Næsepuder til en patientgrænseflade.
BRPI0907036A2 (pt) Conjunto de máscara para fornecer gás para um paciente, e, kit de conjunto de máscara para fornecer um gás para um paciente.
BR112012004176A2 (pt) implemento para cuidado oral
BRPI0906802A2 (pt) Implemento para cuidado oral.
DK2414011T3 (da) Medikamentafgivelsesindretning
BRPI0822825A2 (pt) Implemento para cuidado oral, e, método para formar um implemento para cuidado oral
BR112012003287A2 (pt) implemento para cuidado oral.
BRPI0906366A2 (pt) Inalador
BRPI0917126A2 (pt) implemento para cuidado oral
DK2296732T3 (da) Medikamentafgivelsesindretning
BRPI0817923A2 (pt) Implemento para cuidado oral, e, método
BRPI0822817A2 (pt) Implemento para cuidado oral
BRPI0822833A2 (pt) Implemento para cuidado oral
BRPI0914817A2 (pt) inalador
CR10571A (es) Vacuna virica recombinante
NL301214I2 (nl) Lasmiditan en farmaceutisch aanvaardbare zouten daarvan
BRPI0822868A2 (pt) implemento para cuidado oral
DK2018158T3 (da) Ny racecadotril administrationsform
NO2016019I1 (no) Oritavancin og farmasøytisk aksepterbare salter derav
BRPI0906779A2 (pt) Inalador
DK2350026T3 (da) Sulfoximinsubstituerede anilinopyrimidinderativer som cdk-inhibitorer, fremstilling og anvendelse heraf som lægemiddel

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2508 DE 29-01-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.