BRPI0924921A2 - Métodos de isolar células-tronco mesequimais, de promover proliferação das referidas células e de produção de tecidos diferenciados - Google Patents

Métodos de isolar células-tronco mesequimais, de promover proliferação das referidas células e de produção de tecidos diferenciados

Info

Publication number
BRPI0924921A2
BRPI0924921A2 BRPI0924921-4A BRPI0924921A BRPI0924921A2 BR PI0924921 A2 BRPI0924921 A2 BR PI0924921A2 BR PI0924921 A BRPI0924921 A BR PI0924921A BR PI0924921 A2 BRPI0924921 A2 BR PI0924921A2
Authority
BR
Brazil
Prior art keywords
cells
methods
mesenchymal stem
promoting proliferation
tissue production
Prior art date
Application number
BRPI0924921-4A
Other languages
English (en)
Inventor
Xiao-Dong Chen
Zhongding Lu
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Publication of BRPI0924921A2 publication Critical patent/BRPI0924921A2/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0665Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/90Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
BRPI0924921-4A 2009-03-31 2009-06-19 Métodos de isolar células-tronco mesequimais, de promover proliferação das referidas células e de produção de tecidos diferenciados BRPI0924921A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16519309P 2009-03-31 2009-03-31
PCT/US2009/047981 WO2010114572A1 (en) 2009-03-31 2009-06-19 Isolation of human umbilical cord blood-derived mesenchymal stem cells

Publications (1)

Publication Number Publication Date
BRPI0924921A2 true BRPI0924921A2 (pt) 2015-07-07

Family

ID=42828610

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0924921-4A BRPI0924921A2 (pt) 2009-03-31 2009-06-19 Métodos de isolar células-tronco mesequimais, de promover proliferação das referidas células e de produção de tecidos diferenciados

Country Status (13)

Country Link
US (1) US20120142102A1 (pt)
EP (1) EP2414511B1 (pt)
JP (2) JP2012521780A (pt)
KR (1) KR20120003470A (pt)
CN (1) CN102449141B (pt)
AU (1) AU2009343787B2 (pt)
BR (1) BRPI0924921A2 (pt)
CA (1) CA2756938C (pt)
HK (1) HK1169446A1 (pt)
IL (1) IL215448A0 (pt)
MX (1) MX2011010367A (pt)
SG (1) SG174991A1 (pt)
WO (1) WO2010114572A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9480549B2 (en) 2008-04-25 2016-11-01 Allosource Multi-layer tissue patches
US9358320B2 (en) 2008-04-25 2016-06-07 Allosource Multi-layer tissue patches
US20140286911A1 (en) 2013-03-15 2014-09-25 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
US8940294B2 (en) 2012-03-02 2015-01-27 Tissuetech, Inc. Methods of isolating and culturing stem cells
US9446077B2 (en) 2013-03-13 2016-09-20 Allosource Fascia fibrous compositions and methods for their use and manufacture
EP2970913B1 (en) * 2013-03-15 2018-08-22 LongBoat Explorers AB Cells, methods and apparatuses for umbilical cord blood collection and isolation of cells
JP6700175B2 (ja) * 2013-11-01 2020-05-27 ビービーエイチシー・カンパニー・リミテッドBbhc Co., Ltd. 間葉系幹細胞から誘導多能性幹細胞を製造する方法及びその方法によって製造された誘導多能性幹細胞
KR102161901B1 (ko) 2013-12-06 2020-10-05 알로소스 조직의 시트를 건조하는 방법
KR20160145778A (ko) * 2014-07-07 2016-12-20 메디포스트(주) 작은 크기 줄기세포의 발모 촉진능 및 이의 용도
KR101633019B1 (ko) * 2014-07-25 2016-06-23 주식회사 비비에이치씨 중간엽 줄기세포로부터 유도만능 줄기세포주의 제조방법 및 수득된 세포주
CN105524877A (zh) * 2014-09-29 2016-04-27 四川新生命干细胞科技股份有限公司 一种脐带间充质干细胞的分离方法
WO2016070057A1 (en) 2014-10-30 2016-05-06 Stembiosys, Inc. Methods for maintaining and expanding mesenchymal stem cells on extracellular matrix coated microcarriers
WO2017123312A2 (en) 2015-09-02 2017-07-20 Regeneration Worldwide Company, Inc. Composition and methods of using umbilical cord lining stem cells
US11802272B2 (en) 2015-11-04 2023-10-31 The Board Of Regents Of The University Of Texas System Enrich and amplify highly potent human mesenchymal stem cells from elderly cell populations
JP2019510823A (ja) 2016-03-30 2019-04-18 ステムバイオシス インコーポレイテッド 骨髄間質細胞由来細胞外マトリクスタンパク質抽出物およびその使用
US20180059109A1 (en) * 2016-08-31 2018-03-01 Meridigen Biotech Co., Ltd. Method of distinguishing mesenchymal stem cells and method of determining purity of mesenchymal stem cells
US11542473B2 (en) 2016-10-21 2023-01-03 Amniotics Ab Methods and compositions for generating hematopoietic cells
US10772986B2 (en) 2017-01-26 2020-09-15 Allosource Fascia fibrous compositions and methods for their use and manufacture
CN108715833B (zh) * 2018-06-01 2021-09-14 天晴干细胞股份有限公司 一种负载血小板裂解液的微球制备方法
EP3861103A1 (en) 2018-10-03 2021-08-11 Stembiosys, Inc. Amniotic fluid cell-derived extracellular matrix and uses thereof
US11220671B2 (en) 2019-02-21 2022-01-11 Stembiosys, Inc. Methods for the maturation of cardiomyocytes on amniotic fluid cell-derived ECM, cellular constructs, and uses for cardiotoxicity and proarrhythmic screening of drug compounds
WO2021076042A2 (en) 2019-10-18 2021-04-22 Amniotics Ab Processes and apparatuses for obtaining amniotic mesenchymal stem cells from amniotic fluid and cells derived thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007536935A (ja) * 2004-05-14 2007-12-20 ベクトン・ディキンソン・アンド・カンパニー 間葉幹細胞の無血清増殖のための細胞培養環境
US20070128722A1 (en) * 2005-12-05 2007-06-07 Industrial Technology Research Institute Human mesenchymal stem cells and culturing methods thereof
US8084023B2 (en) * 2007-01-22 2011-12-27 The Board Of Trustees Of The University Of Arkansas Maintenance and propagation of mesenchymal stem cells
US7615374B2 (en) * 2007-09-25 2009-11-10 Wisconsin Alumni Research Foundation Generation of clonal mesenchymal progenitors and mesenchymal stem cell lines under serum-free conditions

Also Published As

Publication number Publication date
EP2414511A1 (en) 2012-02-08
AU2009343787A1 (en) 2011-10-27
MX2011010367A (es) 2011-10-12
CA2756938C (en) 2017-01-31
IL215448A0 (en) 2011-12-29
EP2414511B1 (en) 2017-07-26
AU2009343787B2 (en) 2015-04-02
CN102449141A (zh) 2012-05-09
HK1169446A1 (en) 2013-01-25
JP2012521780A (ja) 2012-09-20
CA2756938A1 (en) 2010-10-07
EP2414511A4 (en) 2014-01-08
US20120142102A1 (en) 2012-06-07
JP2015164430A (ja) 2015-09-17
CN102449141B (zh) 2015-06-03
WO2010114572A1 (en) 2010-10-07
KR20120003470A (ko) 2012-01-10
SG174991A1 (en) 2011-11-28

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.