BRPI0823136A2 - Process for the preparation of substituted phenylalanines - Google Patents

Process for the preparation of substituted phenylalanines

Info

Publication number
BRPI0823136A2
BRPI0823136A2 BRPI0823136-2A BRPI0823136A BRPI0823136A2 BR PI0823136 A2 BRPI0823136 A2 BR PI0823136A2 BR PI0823136 A BRPI0823136 A BR PI0823136A BR PI0823136 A2 BRPI0823136 A2 BR PI0823136A2
Authority
BR
Brazil
Prior art keywords
preparation
substituted phenylalanines
phenylalanines
substituted
Prior art date
Application number
BRPI0823136-2A
Other languages
Portuguese (pt)
Inventor
Hugh Alfred Burgoon
Ramanaiah C Kanamarlapudi
Iain Fraser Pickersgill
Zhi-Cai Shi
Wenxue Wu
Haiming Zhang
Matthew Mangzhu Zhao
Original Assignee
Lexicon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lexicon Pharmaceuticals Inc filed Critical Lexicon Pharmaceuticals Inc
Publication of BRPI0823136A2 publication Critical patent/BRPI0823136A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
BRPI0823136-2A 2008-10-24 2008-10-24 Process for the preparation of substituted phenylalanines BRPI0823136A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/081054 WO2010047712A1 (en) 2008-10-24 2008-10-24 Process for the preparation of substituted phenylalanines

Publications (1)

Publication Number Publication Date
BRPI0823136A2 true BRPI0823136A2 (en) 2015-06-16

Family

ID=40785295

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0823136-2A BRPI0823136A2 (en) 2008-10-24 2008-10-24 Process for the preparation of substituted phenylalanines

Country Status (11)

Country Link
EP (1) EP2358685A1 (en)
JP (1) JP2012506427A (en)
KR (1) KR20110074875A (en)
CN (1) CN102203069A (en)
AU (1) AU2008363274A1 (en)
BR (1) BRPI0823136A2 (en)
CA (1) CA2741563A1 (en)
IL (1) IL211996A0 (en)
MX (1) MX2011004168A (en)
RU (1) RU2011120822A (en)
WO (1) WO2010047712A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015089137A1 (en) * 2013-12-11 2015-06-18 Karos Pharmaceuticals, Inc. Acylguanidines as tryptophan hydroxylase inhibitors
IL302529A (en) 2018-03-08 2023-07-01 Incyte Corp AMINOPYRAZINE DIOL COMPOUNDS AS PI3K-y INHIBITORS
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103265495B (en) * 2005-12-29 2016-11-16 莱西肯医药有限公司 Multicyclic amino acid derivatives and using method thereof
UA99270C2 (en) * 2006-12-12 2012-08-10 Лексикон Фармасьютикалз, Инк. 4-phenyl-6-(2,2,2-trifluoro-1-phenylethoxy)pyrimidine-based compounds and methods of their use

Also Published As

Publication number Publication date
JP2012506427A (en) 2012-03-15
CA2741563A1 (en) 2010-04-29
WO2010047712A1 (en) 2010-04-29
EP2358685A1 (en) 2011-08-24
KR20110074875A (en) 2011-07-04
IL211996A0 (en) 2011-06-30
RU2011120822A (en) 2012-11-27
AU2008363274A1 (en) 2010-04-29
CN102203069A (en) 2011-09-28
MX2011004168A (en) 2011-05-23

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.