BRPI0812875B8 - " método in vitro para indentificar se ou não um indivíduo está sob risco de desenvolvimento de sépsis severa, e, kit de teste - Google Patents
" método in vitro para indentificar se ou não um indivíduo está sob risco de desenvolvimento de sépsis severa, e, kit de testeInfo
- Publication number
- BRPI0812875B8 BRPI0812875B8 BRPI0812875A BRPI0812875A BRPI0812875B8 BR PI0812875 B8 BRPI0812875 B8 BR PI0812875B8 BR PI0812875 A BRPI0812875 A BR PI0812875A BR PI0812875 A BRPI0812875 A BR PI0812875A BR PI0812875 B8 BRPI0812875 B8 BR PI0812875B8
- Authority
- BR
- Brazil
- Prior art keywords
- individual
- risk
- severe sepsis
- test kit
- identify whether
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Electrotherapy Devices (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
MÉTODO IN VITRO PARA IDENTIFICAR SE OU NÃO UM INDIVÍDUO ESTÁ SOB RISCO DE DESENVOLVIMENTO DE SÉPSIS SEVERA, E, KIT DE TESTE. Tem sido demonstrado que o nível de HBP aumenta em indivíduos que subseguentemente desenvolvem sépsis severa. Conformemente, o nível de HBP, a razão de HBP/WBC ou a razão de HBP/NC em um indivíduo podem ser usados para determinar se ou não um indivíduo está sob risco de desenvolvimento de sépsis severa.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0711327.7 | 2007-06-12 | ||
GBGB0711327.7A GB0711327D0 (en) | 2007-06-12 | 2007-06-12 | Diagnostic method |
PCT/EP2008/004743 WO2008151808A1 (en) | 2007-06-12 | 2008-06-12 | Diagnostic method |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0812875A2 BRPI0812875A2 (pt) | 2014-12-09 |
BRPI0812875B1 BRPI0812875B1 (pt) | 2017-12-05 |
BRPI0812875B8 true BRPI0812875B8 (pt) | 2022-07-12 |
Family
ID=38331957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0812875A BRPI0812875B8 (pt) | 2007-06-12 | 2008-06-12 | " método in vitro para indentificar se ou não um indivíduo está sob risco de desenvolvimento de sépsis severa, e, kit de teste |
Country Status (16)
Country | Link |
---|---|
US (3) | US8518648B2 (pt) |
EP (1) | EP2129391B1 (pt) |
JP (1) | JP5166522B2 (pt) |
KR (1) | KR101563997B1 (pt) |
CN (2) | CN101687023B (pt) |
AT (1) | ATE548050T1 (pt) |
AU (1) | AU2008261252B2 (pt) |
BR (1) | BRPI0812875B8 (pt) |
CA (1) | CA2690067C (pt) |
DK (1) | DK2129391T3 (pt) |
ES (1) | ES2380875T3 (pt) |
GB (1) | GB0711327D0 (pt) |
PL (1) | PL2129391T3 (pt) |
PT (1) | PT2129391E (pt) |
SI (1) | SI2129391T1 (pt) |
WO (1) | WO2008151808A1 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0711327D0 (en) | 2007-06-12 | 2007-07-25 | Hansa Medical Ab | Diagnostic method |
US20100240049A1 (en) | 2009-01-16 | 2010-09-23 | Cepheid | Methods of Detecting Cervical Cancer |
JP5488885B2 (ja) * | 2009-10-28 | 2014-05-14 | 国立大学法人 東京大学 | 感染症の疾患マーカー |
GB201016161D0 (en) | 2010-09-24 | 2010-11-10 | Hansa Medical Ab | Diagnostic method |
EP2643483A4 (en) * | 2010-11-26 | 2014-04-30 | Immunexpress Pty Ltd | DIAGNOSTIC AND / OR SCREENING APPROPRIATIONS AND USES THEREFOR |
GB201102108D0 (en) * | 2011-02-07 | 2011-03-23 | Hansa Medical Ab | Diagnostic method |
CA2848873A1 (en) * | 2011-09-16 | 2013-03-21 | Cepheid | Methods of detecting sepsis |
US10260111B1 (en) | 2014-01-20 | 2019-04-16 | Brett Eric Etchebarne | Method of detecting sepsis-related microorganisms and detecting antibiotic-resistant sepsis-related microorganisms in a fluid sample |
US10761093B2 (en) | 2014-10-09 | 2020-09-01 | Texas Tech University System | Microdevice for cell separation utilizing activation phenotype |
CN109541235A (zh) * | 2018-08-19 | 2019-03-29 | 重庆早柒天生物科技股份有限公司 | 肝素结合蛋白和降钙素原二联检测试剂盒及其制备方法 |
EP3960758A4 (en) | 2019-04-24 | 2023-02-15 | Japanese Foundation For Cancer Research | PROCEDURE FOR DETECTING CANCER AND DETECTION REAGENT |
CN111208305B (zh) * | 2020-02-16 | 2023-04-25 | 重庆翼锋生物科技有限公司 | Hbp和pct在败血症诊断试剂制备中的用途 |
CN111951963B (zh) | 2020-07-30 | 2022-09-02 | 中翰盛泰生物技术股份有限公司 | Hbp在covid-19患者的预后风险预警中的应用 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5627262A (en) * | 1989-07-05 | 1997-05-06 | The Board Of Regents Of The University Of Oklahoma | Method and composition for the treatment of septic shock |
US5962241A (en) * | 1989-07-28 | 1999-10-05 | The University Of Arizona | Monoclonal antibody detection of proteins on sperm related to fertility |
US5314804A (en) * | 1992-03-24 | 1994-05-24 | Serim Research Corporation | Test for Helicobacter pylori |
AU703963B2 (en) * | 1994-04-21 | 1999-04-01 | Leukotech A/S | Heparin-binding protein for the treatment of sepsis and processes for its preparation |
US5976536A (en) | 1995-08-09 | 1999-11-02 | Emory University | Neisseria mutants, lipooligosaccharides and immunogenic compositions |
US5778895A (en) | 1997-01-29 | 1998-07-14 | Uab Research Foundation | Method of discriminating bacterial from aseptic meningitis |
US6303321B1 (en) * | 1999-02-11 | 2001-10-16 | North Shore-Long Island Jewish Research Institute | Methods for diagnosing sepsis |
AU2003220034A1 (en) * | 2002-03-08 | 2003-09-22 | Heloise, Anne, Pereira, Ph. D. | An early detection marker for chronic inflammatory associated diseases |
US7655480B2 (en) * | 2002-03-08 | 2010-02-02 | The Board Of Regents Of The University Of Oklahoma | Method for predicting sepsis or an acute infectious inflammatory response |
EP1581556A2 (en) | 2002-08-15 | 2005-10-05 | Leukotech A/S | Bactericidal, anti-apoptotic, pro-inflammatory and anti-inflammatory peptides of heparin-binding protein (hbp) |
JP2006515227A (ja) * | 2003-02-24 | 2006-05-25 | ジーティーシー バイオセラピューティックス インコーポレイテッド | 十字流濾過の方法およびそのための装置 |
US7191068B2 (en) * | 2003-03-25 | 2007-03-13 | Proteogenix, Inc. | Proteomic analysis of biological fluids |
EP1638530A2 (en) * | 2003-06-20 | 2006-03-29 | Royer Biomedical, INC. | Drug polymer complexes |
WO2005028512A1 (en) | 2003-09-19 | 2005-03-31 | Leukotech A/S | Pro-inflammatory and anti-inflammatory antibodies against the heparin-binding protein (hbp) |
US20050196817A1 (en) * | 2004-01-20 | 2005-09-08 | Molecular Staging Inc. | Biomarkers for sepsis |
BRPI0609302A2 (pt) * | 2005-04-15 | 2011-10-11 | Becton Dickinson Co | métodos para prever o desenvolvimento de sepse e para diagnosticar sepse em um indivìduo a ser testado, microarranjo, kit para prever o desenvolvimento de sepse em um indivìduo a ser testado, produto de programa de computador, computador, sistema de computador para determinar se um indivìduo é susceptìvel de desenvolver sepse, sinal digital embutido em uma onda portadora, e, interface gráfica de usuário para determinar se um indivìduo é susceptìvel de desenvolver sepse |
AU2006299417A1 (en) * | 2005-10-03 | 2007-04-12 | Biosite Incorporated | Methods and compositions for diagnosis and/or prognosis in Systemic Inflammatory Response Syndromes |
FR2894675B1 (fr) | 2005-12-14 | 2008-06-27 | Assist Publ Hopitaux De Paris | Distinction des meningites bacteriennes et virales |
GB0711327D0 (en) | 2007-06-12 | 2007-07-25 | Hansa Medical Ab | Diagnostic method |
GB201016161D0 (en) | 2010-09-24 | 2010-11-10 | Hansa Medical Ab | Diagnostic method |
GB201102108D0 (en) | 2011-02-07 | 2011-03-23 | Hansa Medical Ab | Diagnostic method |
-
2007
- 2007-06-12 GB GBGB0711327.7A patent/GB0711327D0/en not_active Ceased
-
2008
- 2008-06-12 CA CA2690067A patent/CA2690067C/en active Active
- 2008-06-12 BR BRPI0812875A patent/BRPI0812875B8/pt active IP Right Grant
- 2008-06-12 CN CN200880019915.XA patent/CN101687023B/zh active Active
- 2008-06-12 WO PCT/EP2008/004743 patent/WO2008151808A1/en active Application Filing
- 2008-06-12 JP JP2010511540A patent/JP5166522B2/ja active Active
- 2008-06-12 DK DK08759218.4T patent/DK2129391T3/da active
- 2008-06-12 PL PL08759218T patent/PL2129391T3/pl unknown
- 2008-06-12 US US12/161,330 patent/US8518648B2/en active Active
- 2008-06-12 KR KR1020097025171A patent/KR101563997B1/ko active IP Right Grant
- 2008-06-12 SI SI200830645T patent/SI2129391T1/sl unknown
- 2008-06-12 EP EP08759218A patent/EP2129391B1/en active Active
- 2008-06-12 AT AT08759218T patent/ATE548050T1/de active
- 2008-06-12 PT PT08759218T patent/PT2129391E/pt unknown
- 2008-06-12 CN CN201310432428.9A patent/CN103543271A/zh active Pending
- 2008-06-12 ES ES08759218T patent/ES2380875T3/es active Active
- 2008-06-12 AU AU2008261252A patent/AU2008261252B2/en active Active
-
2013
- 2013-03-12 US US13/797,749 patent/US20130252347A1/en not_active Abandoned
- 2013-12-02 US US14/094,679 patent/US9784741B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20100305185A1 (en) | 2010-12-02 |
CA2690067A1 (en) | 2008-12-18 |
BRPI0812875A2 (pt) | 2014-12-09 |
ES2380875T3 (es) | 2012-05-21 |
JP2010529468A (ja) | 2010-08-26 |
WO2008151808A1 (en) | 2008-12-18 |
US8518648B2 (en) | 2013-08-27 |
BRPI0812875B1 (pt) | 2017-12-05 |
CA2690067C (en) | 2023-09-19 |
PT2129391E (pt) | 2012-06-06 |
US20130252347A1 (en) | 2013-09-26 |
CN101687023B (zh) | 2016-04-20 |
ATE548050T1 (de) | 2012-03-15 |
US20140187503A1 (en) | 2014-07-03 |
EP2129391B1 (en) | 2012-03-07 |
CN103543271A (zh) | 2014-01-29 |
US9784741B2 (en) | 2017-10-10 |
DK2129391T3 (da) | 2012-06-11 |
KR101563997B1 (ko) | 2015-10-28 |
AU2008261252A1 (en) | 2008-12-18 |
KR20100021578A (ko) | 2010-02-25 |
AU2008261252B2 (en) | 2013-03-14 |
GB0711327D0 (en) | 2007-07-25 |
SI2129391T1 (sl) | 2012-07-31 |
CN101687023A (zh) | 2010-03-31 |
EP2129391A1 (en) | 2009-12-09 |
JP5166522B2 (ja) | 2013-03-21 |
PL2129391T3 (pl) | 2012-09-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] | ||
B25D | Requested change of name of applicant approved |