BRPI0606411A2 - uso de corantes de cianina para o diagnóstico de doenças proliferativas - Google Patents

uso de corantes de cianina para o diagnóstico de doenças proliferativas

Info

Publication number
BRPI0606411A2
BRPI0606411A2 BRPI0606411-6A BRPI0606411A BRPI0606411A2 BR PI0606411 A2 BRPI0606411 A2 BR PI0606411A2 BR PI0606411 A BRPI0606411 A BR PI0606411A BR PI0606411 A2 BRPI0606411 A2 BR PI0606411A2
Authority
BR
Brazil
Prior art keywords
diagnosis
proliferative diseases
cyanine dyes
cyanine
dyes
Prior art date
Application number
BRPI0606411-6A
Other languages
English (en)
Inventor
Kai Licha
Martin Pessel
Malte Bahner
Michael Schirner
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34933224&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0606411(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of BRPI0606411A2 publication Critical patent/BRPI0606411A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A61K49/0034—Indocyanine green, i.e. ICG, cardiogreen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0058—Antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

USO DE CORANTES DE CIANINA PARA O DIAGNóSTICO DE DOENçAS PROLIFERATIVAS. A presente invenção refere-se ao uso do corante de cíanina SF64 para o diagnóstico de doenças proliferativas após administração de menos do que 5 mg/kg de peso corporal.
BRPI0606411-6A 2005-01-07 2006-01-05 uso de corantes de cianina para o diagnóstico de doenças proliferativas BRPI0606411A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05000276A EP1679082A1 (en) 2005-01-07 2005-01-07 Use of cyanine dyes for the diagnosis of proliferative diseases
PCT/EP2006/000058 WO2006072580A1 (en) 2005-01-07 2006-01-05 Use of cyanine dyes for the diagnosis of proliferative diseases

Publications (1)

Publication Number Publication Date
BRPI0606411A2 true BRPI0606411A2 (pt) 2009-06-23

Family

ID=34933224

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606411-6A BRPI0606411A2 (pt) 2005-01-07 2006-01-05 uso de corantes de cianina para o diagnóstico de doenças proliferativas

Country Status (23)

Country Link
EP (2) EP1679082A1 (pt)
JP (1) JP5578765B2 (pt)
KR (1) KR20070092270A (pt)
CN (1) CN101128218A (pt)
AR (1) AR052190A1 (pt)
AU (1) AU2006204496A1 (pt)
BR (1) BRPI0606411A2 (pt)
CA (1) CA2594390C (pt)
CR (1) CR9232A (pt)
DO (1) DOP2006000005A (pt)
GT (1) GT200600001A (pt)
IL (1) IL182499A0 (pt)
MX (1) MX2007008300A (pt)
NO (1) NO20074036L (pt)
NZ (1) NZ554917A (pt)
PA (1) PA8659101A1 (pt)
PE (2) PE20060872A1 (pt)
RU (1) RU2007129919A (pt)
TW (1) TW200635612A (pt)
UA (1) UA89976C2 (pt)
UY (1) UY29323A1 (pt)
WO (1) WO2006072580A1 (pt)
ZA (1) ZA200706533B (pt)

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EP1619501B1 (en) * 2004-07-22 2007-09-26 Bayer Schering Pharma Aktiengesellschaft Use of cyanine dyes for the diagnosis of disease associated with angiogenesis
EP1679082A1 (en) * 2005-01-07 2006-07-12 Schering AG Use of cyanine dyes for the diagnosis of proliferative diseases
EP1743658A1 (en) * 2005-07-14 2007-01-17 Schering Aktiengesellschaft Optical imaging of rheumatoid arthritis
US20100119457A1 (en) * 2007-03-30 2010-05-13 Helmut Lenz Composition of labeled and non-labeled monoclonal antibodies
WO2009012109A2 (en) 2007-07-13 2009-01-22 Emory University Cyanine-containing compounds for cancer imaging and treatment
GB0803477D0 (en) 2008-02-26 2008-04-02 Ge Healthcare As Therapy selection method
CN105288645A (zh) * 2008-06-13 2016-02-03 西塞医疗中心 用于癌症靶向治疗的小分子配体-药物轭合物
GB0814960D0 (en) * 2008-08-15 2008-09-24 Ge Healthcare As Method for detecting dysplasia
WO2011003996A1 (en) 2009-07-09 2011-01-13 F. Hoffmann-La Roche Ag In vivo tumor vasculature imaging
CN102548466A (zh) 2009-07-28 2012-07-04 霍夫曼-拉罗奇有限公司 非侵入性体内光学成像方法
JP2011046662A (ja) 2009-08-28 2011-03-10 Fujifilm Corp 近赤外蛍光造影剤
WO2011025950A2 (en) 2009-08-28 2011-03-03 Visen Medical, Inc. Systems and methods for tomographic imaging in diffuse media using a hybrid inversion technique
JP2011046663A (ja) * 2009-08-28 2011-03-10 Fujifilm Corp 近赤外蛍光造影剤
JP5945226B2 (ja) 2009-09-22 2016-07-05 ビセン メディカル， インコーポレイテッド 拡散媒質の仮想屈折率整合のためのシステムおよび方法
MX2012012736A (es) 2010-05-07 2013-02-26 Hoffmann La Roche Metodo de diagnostico para la deteccion de celulas ex vivo.
EP2683290B1 (en) 2011-03-07 2018-11-07 F.Hoffmann-La Roche Ag Methods for in vivo testing of therapeutic antibodies
JP6385060B2 (ja) 2011-03-07 2018-09-05 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 治療的に活性な抗体のインビボにおける選択
KR101373108B1 (ko) 2012-01-20 2014-03-27 이화여자대학교 산학협력단 폴리메틴 체인에 메조-반응작용기를 갖는 신규한 시아닌 유도체 및 이의 제조방법
CN102608051B (zh) * 2012-02-21 2015-04-08 中国科学院化学研究所 用于诊断白血病的试剂盒
CN102706787B (zh) * 2012-05-24 2015-04-08 中国科学院化学研究所 菁染料的新用途
CN102703569B (zh) * 2012-05-24 2014-04-09 中国科学院化学研究所 菁染料的新用途
US10743768B2 (en) 2012-10-15 2020-08-18 Visen Medical, Inc. Systems, methods, and apparatus for imaging of diffuse media featuring cross-modality weighting of fluorescent and bioluminescent sources
EP2849743B1 (en) 2012-10-26 2019-09-25 Canon Kabushiki Kaisha Cancer cell inhibitory drug and cancer stem-cell detection probe
WO2014092958A1 (en) * 2012-12-10 2014-06-19 Molecular Targeting Technologies, Inc. Compositions and methods of diagnosing ocular diseases
AU2014373656B2 (en) 2013-12-31 2019-12-05 Cornell University Systems, methods, and apparatus for multichannel imaging of fluorescent sources in real time
RU2565645C1 (ru) * 2014-09-05 2015-10-20 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Способ рентгендиагностики глубины инвазии рецидива рака вульвы в мягкие ткани
CA2970719C (en) 2014-12-15 2023-08-01 Memorial Sloan Kettering Cancer Center Cyclic peptides with enhanced nerve-binding selectivity, nanoparticles bound with said cyclic peptides, and use of same for real-time in vivo nerve tissue imaging
CA3007657A1 (en) 2015-12-15 2017-06-22 Memorial Sloan Kettering Cancer Center Imaging systems and methods for tissue differentiation, e.g., for intraoperative visualization
JP2020500863A (ja) 2016-11-30 2020-01-16 メモリアル スローン ケタリング キャンサー センター 阻害剤官能化超小型ナノ粒子およびその方法
EP4015004A1 (en) 2020-12-18 2022-06-22 Phi Pharma SA Proteoglycan specific branched peptides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000095758A (ja) * 1998-09-18 2000-04-04 Schering Ag 近赤外蛍光造影剤および蛍光造影方法
DE19917713A1 (de) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Kurzkettige Peptid-Farbstoffkonjugate als Konstrastmittel für die optische Diagnostik
DE19947559A1 (de) * 1999-09-24 2001-04-19 Schering Ag Antikörper-Farbstoffkonjugate gegen Zielstrukturen der Angiogenese zur intraoperativen Tumorranddarstellung
CA2514131A1 (en) * 2003-01-24 2004-08-05 Schering Ag Hydrophilic, thiol-reactive cyanine dyes and conjugates thereof with biomolecules for fluorescence diagnosis
EP1619501B1 (en) * 2004-07-22 2007-09-26 Bayer Schering Pharma Aktiengesellschaft Use of cyanine dyes for the diagnosis of disease associated with angiogenesis
EP1679082A1 (en) * 2005-01-07 2006-07-12 Schering AG Use of cyanine dyes for the diagnosis of proliferative diseases

Also Published As

Publication number Publication date
MX2007008300A (es) 2007-09-07
CA2594390A1 (en) 2006-07-13
UY29323A1 (es) 2006-10-02
CR9232A (es) 2007-11-23
ZA200706533B (en) 2009-07-29
IL182499A0 (en) 2007-09-20
EP1833513B1 (en) 2013-03-06
TW200635612A (en) 2006-10-16
EP1679082A1 (en) 2006-07-12
CA2594390C (en) 2013-10-22
RU2007129919A (ru) 2009-02-20
AU2006204496A1 (en) 2006-07-13
KR20070092270A (ko) 2007-09-12
AR052190A1 (es) 2007-03-07
DOP2006000005A (es) 2006-07-15
GT200600001A (es) 2006-08-22
PA8659101A1 (es) 2006-09-08
NZ554917A (en) 2010-01-29
EP1833513A1 (en) 2007-09-19
NO20074036L (no) 2007-08-03
PE20060872A1 (es) 2006-10-01
JP5578765B2 (ja) 2014-08-27
CN101128218A (zh) 2008-02-20
PE20100449A1 (es) 2010-07-25
WO2006072580A1 (en) 2006-07-13
JP2008526802A (ja) 2008-07-24
UA89976C2 (ru) 2010-03-25

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 6A. ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2178 DE 02/10/2012.