BRPI0516048A - batelada de um adenovìrus recombinante defectivo em replicação baseado em um sorotipo do subgrupo c - Google Patents

batelada de um adenovìrus recombinante defectivo em replicação baseado em um sorotipo do subgrupo c

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Publication number
BRPI0516048A
BRPI0516048A BRPI0516048-0A BRPI0516048A BRPI0516048A BR PI0516048 A BRPI0516048 A BR PI0516048A BR PI0516048 A BRPI0516048 A BR PI0516048A BR PI0516048 A BRPI0516048 A BR PI0516048A
Authority
BR
Brazil
Prior art keywords
adenovirus
subgroup
serotype
batch
defective recombinant
Prior art date
Application number
BRPI0516048-0A
Other languages
English (en)
Inventor
Menzo Jans Emco Havenga
Dan H Barouch
Original Assignee
Crucell Holland B V E Beth Isr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crucell Holland B V E Beth Isr filed Critical Crucell Holland B V E Beth Isr
Publication of BRPI0516048A publication Critical patent/BRPI0516048A/pt

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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C12N2810/6018—Adenoviridae
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

"BATELADA DE UM ADENOVìRUS RECOMBINANTE DEFECTIVO EM REPLICAçãO BASEADO EM UM SOROTIPO DO SUBGRUPO C". A presente invenção refere-se aos vetores adenovirais recombinantes baseados em adenovírus que encontram imunidade pré-existente em uma minoria da população humana e que hospedam um capsídeo quimérico. O capsídeo quimérico compreende proteínas fibrosas que possuem pelo menos o domínio de espícula de um adenovírus de humano que se liga em Receptor de Coxsackievírus e Adenovírus (CAR) e uma proteína hexon de um sorotipo de adenovírus que encontra imunidade pré-existente em uma minoria da população humana.
BRPI0516048-0A 2004-10-13 2005-10-12 batelada de um adenovìrus recombinante defectivo em replicação baseado em um sorotipo do subgrupo c BRPI0516048A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US61846904P 2004-10-13 2004-10-13
EP04105005 2004-10-13
US69772405P 2005-07-08 2005-07-08
PCT/EP2005/055183 WO2006040330A2 (en) 2004-10-13 2005-10-12 Improved adenoviral vectors and uses thereof

Publications (1)

Publication Number Publication Date
BRPI0516048A true BRPI0516048A (pt) 2008-08-19

Family

ID=35945186

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0516048-0A BRPI0516048A (pt) 2004-10-13 2005-10-12 batelada de um adenovìrus recombinante defectivo em replicação baseado em um sorotipo do subgrupo c

Country Status (12)

Country Link
US (1) US7741099B2 (pt)
EP (1) EP1799836B1 (pt)
KR (1) KR101253363B1 (pt)
AP (1) AP2351A (pt)
AU (1) AU2005293568B2 (pt)
BR (1) BRPI0516048A (pt)
CA (1) CA2583843C (pt)
EA (1) EA010433B1 (pt)
IL (1) IL182330A (pt)
MX (1) MX2007004188A (pt)
NZ (1) NZ553889A (pt)
WO (1) WO2006040330A2 (pt)

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