BRPI0513837A - células hospedeiras geneticamente modificadas e uso das mesmas para produzir compostos isoprenóides - Google Patents
células hospedeiras geneticamente modificadas e uso das mesmas para produzir compostos isoprenóidesInfo
- Publication number
- BRPI0513837A BRPI0513837A BRPI0513837-0A BRPI0513837A BRPI0513837A BR PI0513837 A BRPI0513837 A BR PI0513837A BR PI0513837 A BRPI0513837 A BR PI0513837A BR PI0513837 A BRPI0513837 A BR PI0513837A
- Authority
- BR
- Brazil
- Prior art keywords
- genetically modified
- isoprenoid
- modified host
- host cells
- host cell
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01034—Hydroxymethylglutaryl-CoA reductase (NADPH) (1.1.1.34)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
- C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
- C12Y205/01092—(2Z,6Z)-Farnesyl diphosphate synthase (2.5.1.92)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
- C12Y402/03024—Amorpha-4,11-diene synthase (4.2.3.24)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR122019004903-3A BR122019004903B1 (pt) | 2004-07-27 | 2005-07-21 | Célula hospedeira de saccharomyces cerevisiae geneticamente modificada, composição compreendendo a mesma e método para aumentar a produção de amorfa-4,11-dieno através da via do mevalonato na célula hospedeira |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59200904P | 2004-07-27 | 2004-07-27 | |
US60/592,009 | 2004-07-27 | ||
PCT/US2005/026190 WO2006014837A1 (en) | 2004-07-27 | 2005-07-21 | Genetically modified host cells and use of same for producing isoprenoid compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0513837A true BRPI0513837A (pt) | 2008-05-20 |
BRPI0513837B1 BRPI0513837B1 (pt) | 2021-10-13 |
Family
ID=35787438
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0513837-0A BRPI0513837B1 (pt) | 2004-07-27 | 2005-07-21 | Célula hospedeira saccharomyces cerevisiae geneticamente modificada; composição compreendendo a mesma e método para aumentar a produção de isoprenoides |
BR122019004903-3A BR122019004903B1 (pt) | 2004-07-27 | 2005-07-21 | Célula hospedeira de saccharomyces cerevisiae geneticamente modificada, composição compreendendo a mesma e método para aumentar a produção de amorfa-4,11-dieno através da via do mevalonato na célula hospedeira |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR122019004903-3A BR122019004903B1 (pt) | 2004-07-27 | 2005-07-21 | Célula hospedeira de saccharomyces cerevisiae geneticamente modificada, composição compreendendo a mesma e método para aumentar a produção de amorfa-4,11-dieno através da via do mevalonato na célula hospedeira |
Country Status (11)
Country | Link |
---|---|
US (4) | US8828684B2 (pt) |
EP (2) | EP1778831B1 (pt) |
JP (1) | JP5590769B2 (pt) |
CN (1) | CN101001947A (pt) |
AU (1) | AU2005269556B2 (pt) |
BR (2) | BRPI0513837B1 (pt) |
CA (1) | CA2574593C (pt) |
ES (1) | ES2386359T3 (pt) |
MX (1) | MX2007000973A (pt) |
WO (1) | WO2006014837A1 (pt) |
ZA (1) | ZA200700753B (pt) |
Families Citing this family (58)
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US8828684B2 (en) * | 2004-07-27 | 2014-09-09 | The Regents Of The University Of California | Genetically modified host cells and use of same for producing isoprenoid compounds |
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US20100242345A1 (en) | 2006-05-19 | 2010-09-30 | LS9, Inc | Production of fatty acids & derivatives thereof |
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US8257957B2 (en) | 2006-09-26 | 2012-09-04 | The Regents Of The University Of California | Production of isoprenoids and isoprenoid precursors |
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WO2004011667A2 (en) * | 2002-07-31 | 2004-02-05 | Washington State University Research Foundation | Geranyl diphosphate synthase molecules, and nucleic acid molecules encoding same |
US8828684B2 (en) * | 2004-07-27 | 2014-09-09 | The Regents Of The University Of California | Genetically modified host cells and use of same for producing isoprenoid compounds |
PT1919514E (pt) * | 2005-07-05 | 2012-08-16 | Univ California | Polinucleótidos que codificam enzimas de modificação de isoprenóides e métodos de utilização destes |
KR100751665B1 (ko) * | 2005-12-29 | 2007-08-23 | 주식회사 하이닉스반도체 | 플래쉬 메모리 소자 및 그의 제조방법 |
-
2005
- 2005-07-21 US US11/571,315 patent/US8828684B2/en active Active
- 2005-07-21 EP EP05775484A patent/EP1778831B1/en not_active Revoked
- 2005-07-21 BR BRPI0513837-0A patent/BRPI0513837B1/pt active IP Right Grant
- 2005-07-21 WO PCT/US2005/026190 patent/WO2006014837A1/en active Application Filing
- 2005-07-21 BR BR122019004903-3A patent/BR122019004903B1/pt active IP Right Grant
- 2005-07-21 JP JP2007523676A patent/JP5590769B2/ja active Active
- 2005-07-21 CA CA2574593A patent/CA2574593C/en active Active
- 2005-07-21 CN CNA2005800251193A patent/CN101001947A/zh active Pending
- 2005-07-21 EP EP20100178049 patent/EP2298859A3/en not_active Withdrawn
- 2005-07-21 ES ES05775484T patent/ES2386359T3/es active Active
- 2005-07-21 AU AU2005269556A patent/AU2005269556B2/en active Active
- 2005-07-21 ZA ZA200700753A patent/ZA200700753B/en unknown
- 2005-07-21 MX MX2007000973A patent/MX2007000973A/es active IP Right Grant
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2014
- 2014-08-04 US US14/451,056 patent/US9809829B2/en active Active
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2017
- 2017-10-02 US US15/722,844 patent/US10435717B2/en active Active
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2019
- 2019-08-28 US US16/554,125 patent/US20190382802A1/en not_active Abandoned
Also Published As
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EP2298859A3 (en) | 2011-05-25 |
US20080171378A1 (en) | 2008-07-17 |
CA2574593C (en) | 2016-07-05 |
US20190382802A1 (en) | 2019-12-19 |
CN101001947A (zh) | 2007-07-18 |
MX2007000973A (es) | 2007-04-16 |
JP5590769B2 (ja) | 2014-09-17 |
ZA200700753B (en) | 2008-05-28 |
EP1778831B1 (en) | 2012-05-23 |
BR122019004903B1 (pt) | 2021-11-03 |
EP1778831A1 (en) | 2007-05-02 |
US9809829B2 (en) | 2017-11-07 |
US20180030481A1 (en) | 2018-02-01 |
US8828684B2 (en) | 2014-09-09 |
EP1778831A4 (en) | 2008-02-13 |
BRPI0513837B1 (pt) | 2021-10-13 |
EP2298859A2 (en) | 2011-03-23 |
CA2574593A1 (en) | 2006-02-09 |
ES2386359T3 (es) | 2012-08-17 |
AU2005269556A1 (en) | 2006-02-09 |
WO2006014837A1 (en) | 2006-02-09 |
US10435717B2 (en) | 2019-10-08 |
AU2005269556B2 (en) | 2011-10-27 |
JP2008507974A (ja) | 2008-03-21 |
US20150087042A1 (en) | 2015-03-26 |
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