BRPI0510942A - combinação de antipsicóticos atìpicos e antagonistas do receptor 5-ht1b - Google Patents
combinação de antipsicóticos atìpicos e antagonistas do receptor 5-ht1bInfo
- Publication number
- BRPI0510942A BRPI0510942A BRPI0510942-6A BRPI0510942A BRPI0510942A BR PI0510942 A BRPI0510942 A BR PI0510942A BR PI0510942 A BRPI0510942 A BR PI0510942A BR PI0510942 A BRPI0510942 A BR PI0510942A
- Authority
- BR
- Brazil
- Prior art keywords
- disorder
- pharmaceutically acceptable
- disorders
- syndrome
- sym
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
COMBINAçãO DE ANTIPSICóTICOS ATìPICOS E ANTAGONISTAS DO RECPTOR 5- HT<sym> A presente invenção diz respeito a uma composição farmacêutica para tratar, por exemplo, uma desordem ou condição selecionada do grupo que consiste em hipertensão, depressão desordem da anisedade generalizda, fobia, desordem do estresse pós-traumático, desorem da personalidade evitativa, disfunção sexual, desordens da alimentação, obesidade, dependências químicas, dor de cabeça em salvas, enxaqueca, dor, doença de alzheimer, desordem compusiva obsessiva, desordem do pânico, desordens da memória, doenças de parkinson, desordens endócrinas, ataxia cerebelar, desordens do trato gastrintestinal, sintomas negativos de esquizofrenia, síndrome pré mestrual, síndrome de fibromialgia, incontinência do estresse, síndrome de Tourette, tricotolomania, cleptomania, impotênica masculina, câncer, hemicrânia paroxística crónica e dor de cabeça em um mamífero, preferivelmente um humano,compreendendo (i) um antipsicótico atípico ou um sal farmaceuticamente aceitável destes, (ii) um antagonista do recptor 5-HT <sym> ou um sal farmaceuticamente aceitavel destes, em que o antagonista do recptor 5-HT <sym> é selecionado do grupo que consiste em (A) um composto da fórmula I da maneira descrita na especificação e (B) um composto da formula II a maneira descrita na especificação, e opcionalmente (iii) um carreador farmaceuticamente aceitável..
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56992704P | 2004-05-11 | 2004-05-11 | |
PCT/IB2005/001195 WO2005107808A2 (en) | 2004-05-11 | 2005-04-29 | Combination of atypical antipsychotics and 5-ht1b receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0510942A true BRPI0510942A (pt) | 2007-07-17 |
Family
ID=35094168
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0510942-6A BRPI0510942A (pt) | 2004-05-11 | 2005-04-29 | combinação de antipsicóticos atìpicos e antagonistas do receptor 5-ht1b |
Country Status (7)
Country | Link |
---|---|
US (1) | US20050256112A1 (pt) |
EP (1) | EP1753460A2 (pt) |
JP (1) | JP2007537232A (pt) |
BR (1) | BRPI0510942A (pt) |
CA (1) | CA2565996A1 (pt) |
MX (1) | MXPA06013163A (pt) |
WO (1) | WO2005107808A2 (pt) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8349288B2 (en) * | 2006-12-06 | 2013-01-08 | The Regents Of The University Of California | Process for enhancing the operability of hot gas cleanup for the production of synthesis gas from steam-hydrogasification producer gas |
US20050171088A1 (en) * | 2004-01-30 | 2005-08-04 | Astrazeneca Ab | Treatment of psychoses with dibenzothiazepine antipsychotic |
MX2007004485A (es) * | 2004-10-15 | 2007-06-13 | Organon Nv | Tratamiento de desordenes bipolares y sintomas asociados. |
US7754491B2 (en) * | 2005-12-09 | 2010-07-13 | The Regents Of The University Of Calif. | Sensor for measuring syngas ratios under high temperature and pressure conditions |
GB0618879D0 (en) | 2006-09-26 | 2006-11-01 | Zysis Ltd | Pharmaceutical compositions |
US7645750B2 (en) * | 2006-12-13 | 2010-01-12 | Yung Shin Pharmaceutical Ind. Co., Ltd. | Method of treating symptoms of hormonal variations |
EP2170399A1 (en) * | 2007-06-05 | 2010-04-07 | Synthon B.V. | Intranasal administration of asenapine and pharmaceutical compositions therefor |
US8420624B2 (en) * | 2007-12-04 | 2013-04-16 | Yung Shin Pharm. Ind. Co., Ltd. | Methods for treating or preventing symptoms of hormonal variations |
WO2011109367A2 (en) * | 2010-03-02 | 2011-09-09 | Royster Jr George E | Methods and compositions for treating or preventing symptoms of hormonal variations |
US8461102B2 (en) | 2010-03-02 | 2013-06-11 | George E. Royster, JR. | Methods and compositions for treating and preventing symptoms of hormonal variations |
JP6440625B2 (ja) | 2012-11-14 | 2018-12-19 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 精神***病を処置するための方法および組成物 |
US11337932B2 (en) | 2016-12-20 | 2022-05-24 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene |
AU2017384526B2 (en) | 2016-12-20 | 2023-11-02 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
JP2020525545A (ja) | 2017-06-26 | 2020-08-27 | エルテーエス ローマン テラピー−ジステーメ アーゲー | アセナピンおよびシリコーンアクリルハイブリッドポリマーを含有する経皮治療システム |
US11376337B2 (en) | 2017-11-02 | 2022-07-05 | California Institute Of Technology | Expression of neuropeptides |
EP3704271A4 (en) * | 2017-11-02 | 2021-09-08 | California Institute of Technology | NEUROKININ ANTAGONISTS AND RELATED USES |
CA3101420A1 (en) | 2018-06-20 | 2019-12-26 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3539573A (en) * | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
NL189199C (nl) * | 1975-04-05 | 1993-02-01 | Akzo Nv | Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten. |
NL7605526A (nl) * | 1976-05-24 | 1977-11-28 | Akzo Nv | Nieuwe tetracyclische derivaten. |
FR2415099A1 (fr) * | 1978-01-20 | 1979-08-17 | Ile De France | Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes |
JPS54130587A (en) * | 1978-03-30 | 1979-10-09 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
US4804663A (en) * | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
US4831031A (en) * | 1988-01-22 | 1989-05-16 | Pfizer Inc. | Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity |
US5006528A (en) * | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
US5238945A (en) * | 1989-04-11 | 1993-08-24 | H. Lundbeck A/S | Method of treating psychoses |
GB8908085D0 (en) * | 1989-04-11 | 1989-05-24 | Lundbeck & Co As H | New therapeutic use |
US5229382A (en) * | 1990-04-25 | 1993-07-20 | Lilly Industries Limited | 2-methyl-thieno-benzodiazepine |
EP0746317B1 (en) * | 1994-03-02 | 1998-06-10 | Akzo Nobel N.V. | Sublingual or buccal pharmaceutical composition |
SK131498A3 (en) * | 1996-03-29 | 2000-09-12 | Pfizer | BENZYL(IDENE)-LACTAM DERIVATIVES, THEIR PREPARATION AND THEIR USEì (54) AS SELECTIVE (ANT)AGONISTS OF 5-HT1A- AND/OR 5-HT1D |
TW491847B (en) * | 1996-05-07 | 2002-06-21 | Pfizer | Mesylate dihydrate salts of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2h-indol-2-one |
PT810220E (pt) * | 1996-05-28 | 2002-04-29 | Pfizer | Derivados de arilacrilamida como agonistas ou antigonistas de 5ht1 |
UA56185C2 (uk) * | 1996-09-30 | 2003-05-15 | Пфайзер Інк. | Аралкіл- та аралкіліденгетероциклічні лактами та іміди, фармацевтична композиція та спосіб лікування |
IL127497A (en) * | 1997-12-18 | 2002-07-25 | Pfizer Prod Inc | Medicinal products containing piperazinyl-heterocyclic compounds for the treatment of psychiatric disorders |
PT952154E (pt) * | 1998-04-16 | 2004-12-31 | Pfizer Prod Inc | N-acil- e n-aroil-aralquilamidas |
US6387904B2 (en) * | 1998-05-18 | 2002-05-14 | Pfizer Inc | Method of treating glaucoma and ischemic retinopathy |
US20020049211A1 (en) * | 2000-09-06 | 2002-04-25 | Sobolov-Jaynes Susan Beth | Combination treatment for depression and anxiety |
EP1451166B1 (en) * | 2001-12-07 | 2005-08-10 | Pfizer Products Inc. | Citric acid salt of a therapeutic compound and pharmaceutical compositions thereof |
-
2005
- 2005-04-29 MX MXPA06013163A patent/MXPA06013163A/es not_active Application Discontinuation
- 2005-04-29 CA CA002565996A patent/CA2565996A1/en not_active Abandoned
- 2005-04-29 WO PCT/IB2005/001195 patent/WO2005107808A2/en not_active Application Discontinuation
- 2005-04-29 JP JP2007512553A patent/JP2007537232A/ja active Pending
- 2005-04-29 EP EP05733451A patent/EP1753460A2/en not_active Withdrawn
- 2005-04-29 BR BRPI0510942-6A patent/BRPI0510942A/pt not_active IP Right Cessation
- 2005-05-11 US US11/128,146 patent/US20050256112A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2005107808A2 (en) | 2005-11-17 |
EP1753460A2 (en) | 2007-02-21 |
US20050256112A1 (en) | 2005-11-17 |
MXPA06013163A (es) | 2007-02-13 |
JP2007537232A (ja) | 2007-12-20 |
WO2005107808A3 (en) | 2006-05-11 |
CA2565996A1 (en) | 2005-11-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A E 6 ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE A 8.6 NA RPI 2099 DE 29/03/2011. |