BRPI0510032A - tiofeno heteroaril aminas - Google Patents
tiofeno heteroaril aminasInfo
- Publication number
- BRPI0510032A BRPI0510032A BRPI0510032-1A BRPI0510032A BRPI0510032A BR PI0510032 A BRPI0510032 A BR PI0510032A BR PI0510032 A BRPI0510032 A BR PI0510032A BR PI0510032 A BRPI0510032 A BR PI0510032A
- Authority
- BR
- Brazil
- Prior art keywords
- thiophene
- heteroaryl amines
- amines
- protein kinase
- heteroaryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Abstract
TIOFENO HETEROARIL AMINAS. A presente invenção refere-se a tiofeno heteroaril aminas e seus sais farmacêuticamente aceitáveis que modulam a atividade de proteína cinases e então são esperados ser úteis na prevenção e tratamento de distúrbios celulares relacionados com proteína cinase tal como câncer. Fórmula (I).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57313904P | 2004-05-20 | 2004-05-20 | |
PCT/IB2005/001341 WO2005113548A1 (en) | 2004-05-20 | 2005-05-09 | Thiophene heteroaryl amines |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0510032A true BRPI0510032A (pt) | 2007-10-02 |
Family
ID=34967066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0510032-1A BRPI0510032A (pt) | 2004-05-20 | 2005-05-09 | tiofeno heteroaril aminas |
Country Status (7)
Country | Link |
---|---|
US (1) | US20070293484A1 (pt) |
EP (1) | EP1753750A1 (pt) |
JP (1) | JP2007538063A (pt) |
BR (1) | BRPI0510032A (pt) |
CA (1) | CA2567228A1 (pt) |
MX (1) | MXPA06013338A (pt) |
WO (1) | WO2005113548A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0512324D0 (en) | 2005-06-16 | 2005-07-27 | Novartis Ag | Organic compounds |
CN101272685A (zh) * | 2005-09-27 | 2008-09-24 | Irm责任有限公司 | 包含二芳基胺的化合物和组合物以及它们作为c-kit受体调节剂的用途 |
JP5153645B2 (ja) | 2005-12-21 | 2013-02-27 | ノバルティス アーゲー | Fgf阻害剤であるピリミジニルアリールウレア誘導体 |
DE102005062742A1 (de) | 2005-12-22 | 2007-06-28 | Bayer Schering Pharma Ag | Sulfoximin substituierte Pyrimidine, Verfahren zu deren Herstellung und ihre Verwendung als Arzneimittel |
GB0606774D0 (en) * | 2006-04-03 | 2006-05-10 | Novartis Ag | Organic compounds |
GB0608386D0 (en) * | 2006-04-27 | 2006-06-07 | Senexis Ltd | Compounds |
WO2012083105A1 (en) * | 2010-12-17 | 2012-06-21 | Cocrystal Discovery, Inc. | Inhibitors of hepatitis c virus polymerase |
WO2014055142A1 (en) * | 2012-06-20 | 2014-04-10 | Cocrystal Discovery, Inc. | Inhibitors of hepatitis c virus polymerase |
CN103012284A (zh) * | 2012-12-26 | 2013-04-03 | 无锡捷化医药科技有限公司 | 一种2-氨基-5-溴嘧啶类化合物的制备方法 |
TWI731854B (zh) | 2015-03-23 | 2021-07-01 | 美商共結晶製藥公司 | C型肝炎病毒聚合酶之抑制劑 |
JP2020517618A (ja) | 2017-04-21 | 2020-06-18 | エピザイム,インコーポレイティド | Ehmt2阻害剤との併用療法 |
WO2023218241A1 (en) * | 2022-05-13 | 2023-11-16 | Voronoi Inc. | Heteroaryl derivative compounds, and pharmaceutical composition comprising thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002083667A2 (en) * | 2001-04-13 | 2002-10-24 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases |
WO2003028731A1 (en) * | 2001-10-04 | 2003-04-10 | Smithkline Beecham Corporation | Chk1 kinase inhibitors |
US20040122016A1 (en) * | 2002-10-30 | 2004-06-24 | Jingrong Cao | Compositions useful as inhibitors of rock and other protein kinases |
-
2005
- 2005-05-09 US US11/630,588 patent/US20070293484A1/en not_active Abandoned
- 2005-05-09 JP JP2007517482A patent/JP2007538063A/ja not_active Withdrawn
- 2005-05-09 EP EP05738354A patent/EP1753750A1/en not_active Withdrawn
- 2005-05-09 MX MXPA06013338A patent/MXPA06013338A/es not_active Application Discontinuation
- 2005-05-09 BR BRPI0510032-1A patent/BRPI0510032A/pt not_active Application Discontinuation
- 2005-05-09 WO PCT/IB2005/001341 patent/WO2005113548A1/en active Application Filing
- 2005-05-09 CA CA002567228A patent/CA2567228A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20070293484A1 (en) | 2007-12-20 |
CA2567228A1 (en) | 2005-12-01 |
EP1753750A1 (en) | 2007-02-21 |
WO2005113548A1 (en) | 2005-12-01 |
JP2007538063A (ja) | 2007-12-27 |
MXPA06013338A (es) | 2007-02-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |