BRPI0417717A - composto, composição farmacêutica, e, uso de um composto - Google Patents
composto, composição farmacêutica, e, uso de um compostoInfo
- Publication number
- BRPI0417717A BRPI0417717A BRPI0417717-7A BRPI0417717A BRPI0417717A BR PI0417717 A BRPI0417717 A BR PI0417717A BR PI0417717 A BRPI0417717 A BR PI0417717A BR PI0417717 A BRPI0417717 A BR PI0417717A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- pharmaceutical composition
- compounds
- therapeutic use
- novel glp
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
"COMPOSTO, COMPOSIçãO FARMACêUTICA, E, USO DE UM COMPOSTO" Novos compostos de GLP-1 e seu uso terapêutico.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200301885 | 2003-12-18 | ||
DKPA200401090 | 2004-07-09 | ||
PCT/DK2004/000886 WO2005058954A1 (en) | 2003-12-18 | 2004-12-17 | Novel glp-1 compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0417717A true BRPI0417717A (pt) | 2007-04-03 |
Family
ID=34702152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0417717-7A BRPI0417717A (pt) | 2003-12-18 | 2004-12-17 | composto, composição farmacêutica, e, uso de um composto |
Country Status (12)
Country | Link |
---|---|
US (2) | US20070042956A1 (pt) |
EP (1) | EP1704165B1 (pt) |
JP (1) | JP2007537141A (pt) |
KR (1) | KR20060135661A (pt) |
AT (1) | ATE461217T1 (pt) |
AU (1) | AU2004298424A1 (pt) |
BR (1) | BRPI0417717A (pt) |
CA (1) | CA2549582A1 (pt) |
DE (1) | DE602004026113D1 (pt) |
MX (1) | MXPA06006745A (pt) |
RU (1) | RU2006120079A (pt) |
WO (1) | WO2005058954A1 (pt) |
Families Citing this family (76)
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PL1605897T3 (pl) | 2003-03-19 | 2012-12-31 | Lilly Co Eli | Związki będące połączeniem GLP-1 z poli(glikolem etylenowym) |
RU2006120079A (ru) | 2003-12-18 | 2008-01-27 | Ново Нордиск А/С (DK) | Производные глюкагоноподобного пептида-1 (glp-1) |
TWI376234B (en) | 2005-02-01 | 2012-11-11 | Msd Oss Bv | Conjugates of a polypeptide and an oligosaccharide |
CN101123992A (zh) * | 2005-02-16 | 2008-02-13 | 诺和诺德公司 | 缀合有结构完全确定的支化聚合物的促胰岛素剂的衍生物 |
WO2006097538A1 (en) | 2005-03-18 | 2006-09-21 | Novo Nordisk A/S | Extended glp-1 compounds |
TWI372629B (en) | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
WO2007047834A2 (en) * | 2005-10-18 | 2007-04-26 | Biocon Limited | Oral peptide conjugates for metabolic diseases |
EP1942941A1 (en) * | 2005-10-26 | 2008-07-16 | Eli Lilly And Company | Selective vpac2 receptor peptide agonists |
ES2507098T3 (es) | 2005-11-07 | 2014-10-14 | Indiana University Research And Technology Corporation | Análogos de glucagón que muestran solubilidad y estabilidad fisiológicas |
JP5096363B2 (ja) | 2005-12-16 | 2012-12-12 | ネクター セラピューティックス | Glp−1のポリマ複合体 |
EP2574624A1 (en) * | 2006-04-20 | 2013-04-03 | Amgen Inc. | GLP-1 compounds |
FR2904627B1 (fr) * | 2006-08-04 | 2008-11-07 | Pasteur Institut | Nouveaux peptides actives, purifies et isoles, derives du recepteur cd4 (mini-cd4) et leur procece de preparation |
CN101125207B (zh) | 2006-11-14 | 2012-09-05 | 上海华谊生物技术有限公司 | 带有聚乙二醇基团的艾塞丁或其类似物及其制剂和用途 |
EP2124974B1 (en) * | 2007-01-05 | 2017-03-15 | Indiana University Research and Technology Corporation | Glucagon analogs exhibiting enhanced solubility in physiological ph buffers |
US8454971B2 (en) | 2007-02-15 | 2013-06-04 | Indiana University Research And Technology Corporation | Glucagon/GLP-1 receptor co-agonists |
EP2679597A1 (en) * | 2007-09-05 | 2014-01-01 | Novo Nordisk A/S | Glucagon-like peptide-1 derivatives and their pharmaceutical use |
EP2190460B1 (en) | 2007-09-05 | 2014-12-17 | Novo Nordisk A/S | Peptides derivatized with a-b-c-d- and their therapeutical use |
CN101842386A (zh) | 2007-09-05 | 2010-09-22 | 诺沃-诺迪斯克有限公司 | 截短的glp-1衍生物和它们的治疗用途 |
GB0717399D0 (en) * | 2007-09-07 | 2007-10-17 | Uutech Ltd | Use of GLP-1 analogues for the treatment of disorders associated with dysfunctional synaptic transmission |
EP2200626A4 (en) * | 2007-09-07 | 2012-02-15 | Ipsen Pharma Sas | ANALOGUE OF EXENDIN-4 AND EXENDIN-3 |
WO2009058662A2 (en) * | 2007-10-30 | 2009-05-07 | Indiana University Research And Technology Corporation | Glucagon antagonists |
JP5771005B2 (ja) * | 2007-10-30 | 2015-08-26 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | グルカゴンアンタゴニスト及びglp−1アゴニスト活性を示す化合物 |
CN101983066B (zh) * | 2008-01-30 | 2016-06-29 | 印第安那大学科技研究公司 | 基于酯的胰岛素前药 |
EP2087911A1 (en) * | 2008-02-06 | 2009-08-12 | Institut Pasteur | Conjugated molecules comprising a peptide derived from the CD4 receptor coupled to a polyanion for the treatment of AIDS |
WO2009152289A1 (en) * | 2008-06-11 | 2009-12-17 | Indiana University Research And Technology Corporation | Methods for enhancing adsorption of molecules |
JP5753779B2 (ja) * | 2008-06-17 | 2015-07-22 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | 生理学的pHの緩衝液中で向上した溶解性及び安定性を示すグルカゴン類縁体 |
US8546327B2 (en) | 2008-06-17 | 2013-10-01 | Indiana University Research And Technology Corporation | Glucagon/GLP-1 receptor co-agonists |
PL2300035T3 (pl) * | 2008-06-17 | 2016-04-29 | Univ Indiana Res & Tech Corp | Mieszani agoniści na bazie GIP do leczenia zaburzeń metabolicznych i otyłości |
CA2733200A1 (en) | 2008-08-06 | 2010-02-11 | Novo Nordisk Health Care Ag | Conjugated proteins with prolonged in vivo efficacy |
TW201012829A (en) * | 2008-09-22 | 2010-04-01 | Ipsen Mfg Ireland Ltd | Process for the synthesis of (Aib8,35)hGLP-1(7-36)-NH2 |
KR20110110174A (ko) | 2008-12-19 | 2011-10-06 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 | 아미드 기반 글루카곤 슈퍼패밀리 펩티드 프로드럭 |
CN102292349B (zh) | 2009-01-22 | 2016-04-13 | 诺沃—诺迪斯克保健股份有限公司 | 稳定的生长激素化合物 |
MX2011013625A (es) | 2009-06-16 | 2012-01-20 | Univ Indiana Res & Tech Corp | Compuestos glucagon activo de receptor de gip. |
CN102612376A (zh) | 2009-08-06 | 2012-07-25 | 诺沃-诺迪斯克保健股份有限公司 | 具有延长的体内功效的生长激素 |
WO2011080102A2 (en) | 2009-12-16 | 2011-07-07 | Novo Nordisk A/S | Glp-1 analogues and derivatives |
WO2011075393A2 (en) | 2009-12-18 | 2011-06-23 | Indiana University Research And Technology Corporation | Glucagon/glp-1 receptor co-agonists |
EP2525833A2 (en) | 2010-01-22 | 2012-11-28 | Novo Nordisk Health Care AG | Stable growth hormone compounds |
CN106139158A (zh) | 2010-01-22 | 2016-11-23 | 诺沃—诺迪斯克保健股份有限公司 | 体内功效延长的生长激素 |
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HRP20231613T1 (hr) | 2012-03-22 | 2024-03-15 | Novo Nordisk A/S | Pripravci koji sadrže sredstvo za unošenje i njihova priprava |
US11274135B2 (en) | 2012-05-08 | 2022-03-15 | Novo Nordisk A/S | Double-acylated GLP-1 derivatives |
JP6250034B2 (ja) * | 2012-05-08 | 2017-12-20 | ノヴォ ノルディスク アー/エス | 二重アシル化されたglp−1誘導体 |
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WO2020127476A1 (en) | 2018-12-19 | 2020-06-25 | Krka, D.D., Novo Mesto | Pharmaceutical composition comprising glp-1 analogue |
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CN115461044A (zh) | 2020-04-29 | 2022-12-09 | 诺和诺德股份有限公司 | 包含glp-1激动剂和组氨酸的固体组合物 |
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PL1605897T3 (pl) * | 2003-03-19 | 2012-12-31 | Lilly Co Eli | Związki będące połączeniem GLP-1 z poli(glikolem etylenowym) |
PT2107069E (pt) | 2003-08-05 | 2013-04-23 | Novo Nordisk As | Novos derivados de insulina |
JP2008505048A (ja) * | 2003-09-19 | 2008-02-21 | ザ スクリップス リサーチ インスティテュート | 4E10Fabフラグメント複合体の広範囲中和性抗HIV抗体構造に結合するペプチド、それらの使用、それら由来の組成物 |
RU2006120079A (ru) | 2003-12-18 | 2008-01-27 | Ново Нордиск А/С (DK) | Производные глюкагоноподобного пептида-1 (glp-1) |
DK1909871T4 (da) | 2005-07-27 | 2014-05-26 | Novo Nordisk As | Sprøjteanordning med en dosisbegrænsende mekanisme og en yderligere sikkerhedmekanisme |
RU2491102C2 (ru) | 2008-01-23 | 2013-08-27 | Ново Нордиск А/С | Устройство для инъекции установленной дозы жидкого лекарственного средства |
-
2004
- 2004-12-17 RU RU2006120079/13A patent/RU2006120079A/ru unknown
- 2004-12-17 CA CA002549582A patent/CA2549582A1/en not_active Abandoned
- 2004-12-17 JP JP2006544220A patent/JP2007537141A/ja not_active Withdrawn
- 2004-12-17 KR KR1020067011699A patent/KR20060135661A/ko not_active Application Discontinuation
- 2004-12-17 BR BRPI0417717-7A patent/BRPI0417717A/pt not_active IP Right Cessation
- 2004-12-17 WO PCT/DK2004/000886 patent/WO2005058954A1/en active Application Filing
- 2004-12-17 EP EP04803037A patent/EP1704165B1/en not_active Revoked
- 2004-12-17 AU AU2004298424A patent/AU2004298424A1/en not_active Abandoned
- 2004-12-17 MX MXPA06006745A patent/MXPA06006745A/es not_active Application Discontinuation
- 2004-12-17 DE DE602004026113T patent/DE602004026113D1/de active Active
- 2004-12-17 AT AT04803037T patent/ATE461217T1/de not_active IP Right Cessation
-
2006
- 2006-06-16 US US11/454,804 patent/US20070042956A1/en not_active Abandoned
-
2012
- 2012-05-16 US US13/473,154 patent/US9920106B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
RU2006120079A (ru) | 2008-01-27 |
WO2005058954A1 (en) | 2005-06-30 |
ATE461217T1 (de) | 2010-04-15 |
US20120289453A1 (en) | 2012-11-15 |
MXPA06006745A (es) | 2006-08-18 |
EP1704165B1 (en) | 2010-03-17 |
DE602004026113D1 (de) | 2010-04-29 |
CA2549582A1 (en) | 2005-06-30 |
US20070042956A1 (en) | 2007-02-22 |
JP2007537141A (ja) | 2007-12-20 |
KR20060135661A (ko) | 2006-12-29 |
US9920106B2 (en) | 2018-03-20 |
EP1704165A1 (en) | 2006-09-27 |
AU2004298424A1 (en) | 2005-06-30 |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
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