BRPI0415505A - agente terapêutico para mesotelioma - Google Patents

agente terapêutico para mesotelioma

Info

Publication number
BRPI0415505A
BRPI0415505A BRPI0415505-0A BRPI0415505A BRPI0415505A BR PI0415505 A BRPI0415505 A BR PI0415505A BR PI0415505 A BRPI0415505 A BR PI0415505A BR PI0415505 A BRPI0415505 A BR PI0415505A
Authority
BR
Brazil
Prior art keywords
therapeutic agent
mesothelioma
mesothelioma therapeutic
interleukin
antagonist
Prior art date
Application number
BRPI0415505-0A
Other languages
English (en)
Inventor
Norihiro Nishimoto
Tadamitsu Kishimoto
Yasuo Adachi
Koichi Takayama
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34463281&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0415505(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of BRPI0415505A publication Critical patent/BRPI0415505A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/248IL-6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Mobile Radio Communication Systems (AREA)

Abstract

"AGENTE TERAPêUTICO PARA MESOTELIOMA". A presente invenção proporciona um agente terapêutico para mesotelioma que contém um antagonista de interleucina-6 (IL-6) tal como anticorpo para receptor de IL-6 (IL-6R), e um inibidor de crescimento celular de mesotelioma que contém um antagonista de IL-6 tal como anticorpo para IL-6R.
BRPI0415505-0A 2003-10-17 2004-10-15 agente terapêutico para mesotelioma BRPI0415505A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003358152 2003-10-17
PCT/JP2004/015674 WO2005037315A1 (ja) 2003-10-17 2004-10-15 中皮腫治療剤

Publications (1)

Publication Number Publication Date
BRPI0415505A true BRPI0415505A (pt) 2006-12-12

Family

ID=34463281

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0415505-0A BRPI0415505A (pt) 2003-10-17 2004-10-15 agente terapêutico para mesotelioma

Country Status (23)

Country Link
US (2) US20070134242A1 (pt)
EP (1) EP1690550B1 (pt)
JP (1) JP4651541B2 (pt)
KR (1) KR101193708B1 (pt)
CN (1) CN1874790B (pt)
AR (1) AR046290A1 (pt)
AU (1) AU2004281139B2 (pt)
BR (1) BRPI0415505A (pt)
CA (1) CA2542691C (pt)
DK (1) DK1690550T3 (pt)
ES (1) ES2392824T3 (pt)
HK (1) HK1096588A1 (pt)
IL (1) IL174909A (pt)
MX (1) MXPA06003768A (pt)
MY (1) MY149856A (pt)
NO (1) NO20061906L (pt)
NZ (1) NZ546557A (pt)
PL (1) PL1690550T3 (pt)
RU (2) RU2392967C2 (pt)
SI (1) SI1690550T1 (pt)
TW (1) TWI350175B (pt)
WO (1) WO2005037315A1 (pt)
ZA (1) ZA200602973B (pt)

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UA80091C2 (en) 2001-04-02 2007-08-27 Chugai Pharmaceutical Co Ltd Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist
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BRPI0617664B8 (pt) 2005-10-21 2021-05-25 Chugai Pharmaceutical Co Ltd uso de um anticorpo que reconhece a il-6 para a produção de uma composição farmacêutica para tratar o enfarte do miocárdio ou suprimir a remodelagem ventricular esquerda depois do enfarte do miocárdio
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CN102256623A (zh) 2008-06-05 2011-11-23 独立行政法人国立癌症研究中心 神经浸润抑制剂
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US8420089B2 (en) 2008-11-25 2013-04-16 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
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Also Published As

Publication number Publication date
CA2542691A1 (en) 2005-04-28
US20080274106A1 (en) 2008-11-06
MXPA06003768A (es) 2006-06-23
CN1874790B (zh) 2011-11-16
IL174909A (en) 2010-11-30
CN1874790A (zh) 2006-12-06
NZ546557A (en) 2010-01-29
AU2004281139B2 (en) 2011-01-20
IL174909A0 (en) 2006-08-20
CA2542691C (en) 2013-09-24
RU2554942C2 (ru) 2015-07-10
AU2004281139A1 (en) 2005-04-28
DK1690550T3 (da) 2012-11-05
PL1690550T3 (pl) 2013-01-31
TWI350175B (en) 2011-10-11
TW200517126A (en) 2005-06-01
KR20070029632A (ko) 2007-03-14
US20070134242A1 (en) 2007-06-14
EP1690550A4 (en) 2009-07-15
ES2392824T3 (es) 2012-12-14
SI1690550T1 (sl) 2012-12-31
JPWO2005037315A1 (ja) 2006-12-28
EP1690550B1 (en) 2012-08-08
WO2005037315A1 (ja) 2005-04-28
JP4651541B2 (ja) 2011-03-16
RU2006116896A (ru) 2007-12-10
EP1690550A1 (en) 2006-08-16
AR046290A1 (es) 2005-11-30
MY149856A (en) 2013-10-31
US8802092B2 (en) 2014-08-12
KR101193708B1 (ko) 2012-10-22
NO20061906L (no) 2006-06-21
HK1096588A1 (en) 2007-06-08
RU2010102911A (ru) 2011-08-10
RU2392967C2 (ru) 2010-06-27
ZA200602973B (en) 2007-07-25

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