BRPI0410876B8 - composição, proteína de fusão, molécula de cdna, vetor, célula hospedeira procariótica recombinante, método para preparar uma molécula inibidora do complemento, e, usos de uma composição e de uma proteína de fusão - Google Patents
composição, proteína de fusão, molécula de cdna, vetor, célula hospedeira procariótica recombinante, método para preparar uma molécula inibidora do complemento, e, usos de uma composição e de uma proteína de fusãoInfo
- Publication number
- BRPI0410876B8 BRPI0410876B8 BRPI0410876A BRPI0410876A BRPI0410876B8 BR PI0410876 B8 BRPI0410876 B8 BR PI0410876B8 BR PI0410876 A BRPI0410876 A BR PI0410876A BR PI0410876 A BRPI0410876 A BR PI0410876A BR PI0410876 B8 BRPI0410876 B8 BR PI0410876B8
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- fusion protein
- molecule
- vector
- making
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43527—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from ticks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
- G01N2333/43552—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from insects
- G01N2333/43556—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from insects from ticks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4716—Complement proteins, e.g. anaphylatoxin, C3a, C5a
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/42—Poisoning, e.g. from bites or stings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Insects & Arthropods (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Virology (AREA)
- Diabetes (AREA)
Abstract
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0312619.0 | 2003-06-02 | ||
GB0312619A GB0312619D0 (en) | 2003-06-02 | 2003-06-02 | Complement inhibitors |
GB0327386A GB0327386D0 (en) | 2003-11-25 | 2003-11-25 | Complement inhibitors |
GB0327386.9 | 2003-11-25 | ||
PCT/GB2004/002341 WO2004106369A2 (en) | 2003-06-02 | 2004-06-02 | Complement inhibitors from ticks |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0410876A BRPI0410876A (pt) | 2006-07-04 |
BRPI0410876B1 BRPI0410876B1 (pt) | 2020-11-03 |
BRPI0410876B8 true BRPI0410876B8 (pt) | 2023-01-24 |
Family
ID=33492257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0410876A BRPI0410876B8 (pt) | 2003-06-02 | 2004-06-02 | composição, proteína de fusão, molécula de cdna, vetor, célula hospedeira procariótica recombinante, método para preparar uma molécula inibidora do complemento, e, usos de uma composição e de uma proteína de fusão |
Country Status (13)
Country | Link |
---|---|
US (5) | US7884188B2 (pt) |
EP (1) | EP1629098B1 (pt) |
JP (1) | JP4772667B2 (pt) |
AT (1) | ATE427356T1 (pt) |
AU (1) | AU2004242759B2 (pt) |
BR (1) | BRPI0410876B8 (pt) |
CA (1) | CA2526083C (pt) |
DE (1) | DE602004020334D1 (pt) |
ES (1) | ES2324993T3 (pt) |
HK (1) | HK1085511A1 (pt) |
MX (1) | MXPA05012880A (pt) |
NZ (1) | NZ544163A (pt) |
WO (1) | WO2004106369A2 (pt) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA05012880A (es) * | 2003-06-02 | 2006-02-22 | Evolutec Ltd | Inhibidores de complemento. |
PT1713503E (pt) | 2004-02-10 | 2013-11-14 | Nat Jewish Health | Inibição do factor b, a via alternativa do complemento e métodos relacionados |
KR20130100207A (ko) | 2005-02-14 | 2013-09-09 | 유니버시티 오브 아이오와 리써치 파운데이션 | 연령관련 황반 변성의 치료 및 진단용 방법 및 시약 |
CN101227924A (zh) | 2005-05-26 | 2008-07-23 | 科罗拉多大学评议会 | 用于治疗外伤性脑损伤、脊髓损伤及相关病症的补体旁路抑制 |
GB0518443D0 (en) | 2005-09-09 | 2005-10-19 | Evolutec Ltd | Method of treating myasthenia gravis |
BRPI0619747B8 (pt) | 2005-12-12 | 2021-05-25 | Ac Immune Sa | método para produzir uma composição de vacina terapêutica, construto antigênico, composição de vacina, usos de um construto antigênico, e, método para preparar e produzir um medicamento para o tratamento de uma condição ou doença associada com amilóide |
JP2010502687A (ja) * | 2006-09-08 | 2010-01-28 | ヴァーレイ・リミテッド | 呼吸器疾患の治療方法 |
GB0617734D0 (en) * | 2006-09-08 | 2006-10-18 | Evolutec Ltd | Method of treating peripheral nerve disorders |
PL2148691T3 (pl) * | 2007-02-05 | 2015-12-31 | Apellis Pharmaceuticals Inc | Analogi kompstatyny do stosowania w leczeniu stanów zapalnych układu oddechowego |
CN101668773B (zh) | 2007-03-14 | 2016-08-31 | 亚力史制药公司 | 人工程化抗b因子抗体 |
GB0802116D0 (en) * | 2008-02-05 | 2008-03-12 | Natural Enviromental Res Counc | Treatment |
US20090324585A1 (en) * | 2008-06-12 | 2009-12-31 | The Trustees of the Leland Standford Junior University | Complement inhibitory agents as therapeutics in posttraumatic and degenerative arthritis |
GB0906779D0 (en) | 2009-04-20 | 2009-06-03 | Natural Environment Res Council | Composition |
US9291622B2 (en) | 2009-05-21 | 2016-03-22 | Apellis Pharmaceuticals, Inc. | Complement assays and uses thereof |
CN101928709B (zh) * | 2009-06-24 | 2012-05-23 | 中国农业科学院上海兽医研究所 | 一种亚洲璃眼蜱的组胺结合蛋白HaHBP的基因序列和重组表达与应用 |
WO2011003098A1 (en) | 2009-07-02 | 2011-01-06 | Musc Foundation For Research Development | Methods of stimulating liver regeneration |
JP5840623B2 (ja) * | 2010-01-08 | 2016-01-06 | ヴォリューション イミュノ ファーマシューティカルズ エスエイ | 気道のウイルス感染症の治療に用いるev576 |
US20130058931A1 (en) | 2010-03-11 | 2013-03-07 | University Of Louisville Research Foundation, Inc. | Methods of predicting and decreasing the risk of pregnancy loss |
WO2012078968A2 (en) | 2010-12-10 | 2012-06-14 | Lifeline Scientific, Inc. | Machine perfusion with complement inhibitors |
US8961981B2 (en) | 2011-06-20 | 2015-02-24 | Saint Louis University | Targeting the neuromuscular junction for treatment |
CA2840270C (en) | 2011-06-22 | 2023-09-26 | Apellis Pharmaceuticals, Inc. | Methods of treating chronic disorders with complement inhibitors |
US9808502B2 (en) | 2012-02-20 | 2017-11-07 | Swedish Orphan Biovitrum Ab (Publ) | Polypeptides binding to human complement C5 |
EP2855529A4 (en) | 2012-05-24 | 2015-12-09 | Alexion Pharma Inc | HUMANIZED ANTI-FACTOR B ANTIBODIES |
GB201410116D0 (en) | 2014-06-06 | 2014-07-23 | Volution Immuno Pharmaceuticals Sa | Method of treatment |
GB201602802D0 (en) | 2016-02-17 | 2016-03-30 | Volution Immuno Pharmaceuticals Sa | Method of treatment |
WO2017210537A1 (en) | 2016-06-02 | 2017-12-07 | The Cleveland Clinic Foundation | Complement inhibition for improving cell viability |
JP7102353B2 (ja) | 2016-06-14 | 2022-07-19 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 抗c5抗体及びそれらの使用 |
GB201706406D0 (en) | 2017-04-21 | 2017-06-07 | Volution Immuno Pharmaceuticals Sa | Method of treatment |
WO2018193122A1 (en) | 2017-04-21 | 2018-10-25 | Volution Immuno Pharmaceuticals Sa | Coversin for the treatment of autoimmune blistering diseases |
SG11202004662RA (en) | 2017-12-13 | 2020-06-29 | Regeneron Pharma | Anti-c5 antibody combinations and uses thereof |
WO2020053206A1 (en) | 2018-09-10 | 2020-03-19 | Volution Immuno Pharmaceuticals Sa | Coversin for use in the treatment of rheumatic diseases |
GB201905810D0 (en) | 2019-04-25 | 2019-06-05 | Volution Immuno Pharmaceuticals Sa | Method of treatment |
CA3153803A1 (en) | 2019-09-27 | 2021-04-01 | Volution Immuno Pharmaceuticals Sa | Method of treatment of hematopoietic stem cell transplant associated thrombotic microangiopathy (hsct-tma) |
GB202218084D0 (en) | 2022-12-01 | 2023-01-18 | Volution Immuno Pharmaceuticals Sa | Fusion proteins |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU3734093A (en) | 1992-02-27 | 1993-09-13 | Merck & Co., Inc. | Protein for inhibiting collagen-stimulated platelet aggregation |
US7884066B2 (en) * | 1999-10-05 | 2011-02-08 | The Regents Of The University Of California | NELL-1 enhanced bone mineralization |
US7785601B2 (en) * | 2002-12-31 | 2010-08-31 | Sygnis Bioscience Gmbh & Co. Kg | Methods of treating neurological conditions with hematopoietic growth factors |
MXPA05012880A (es) * | 2003-06-02 | 2006-02-22 | Evolutec Ltd | Inhibidores de complemento. |
-
2004
- 2004-06-02 MX MXPA05012880A patent/MXPA05012880A/es not_active Application Discontinuation
- 2004-06-02 US US10/558,937 patent/US7884188B2/en active Active
- 2004-06-02 NZ NZ544163A patent/NZ544163A/en unknown
- 2004-06-02 DE DE602004020334T patent/DE602004020334D1/de not_active Expired - Lifetime
- 2004-06-02 AU AU2004242759A patent/AU2004242759B2/en not_active Expired
- 2004-06-02 WO PCT/GB2004/002341 patent/WO2004106369A2/en active Application Filing
- 2004-06-02 CA CA2526083A patent/CA2526083C/en not_active Expired - Lifetime
- 2004-06-02 EP EP04735758A patent/EP1629098B1/en not_active Expired - Lifetime
- 2004-06-02 AT AT04735758T patent/ATE427356T1/de active
- 2004-06-02 JP JP2006508386A patent/JP4772667B2/ja not_active Expired - Lifetime
- 2004-06-02 ES ES04735758T patent/ES2324993T3/es not_active Expired - Lifetime
- 2004-06-02 BR BRPI0410876A patent/BRPI0410876B8/pt active IP Right Grant
-
2006
- 2006-05-15 HK HK06105580.9A patent/HK1085511A1/xx not_active IP Right Cessation
-
2011
- 2011-02-07 US US12/931,640 patent/US8993264B2/en active Active
-
2015
- 2015-02-18 US US14/624,909 patent/US9834585B2/en not_active Expired - Lifetime
-
2017
- 2017-08-17 US US15/679,425 patent/US20180127472A1/en not_active Abandoned
-
2022
- 2022-01-05 US US17/569,374 patent/US20220363726A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP4772667B2 (ja) | 2011-09-14 |
WO2004106369A3 (en) | 2005-02-17 |
BRPI0410876B1 (pt) | 2020-11-03 |
US20160096870A1 (en) | 2016-04-07 |
JP2007536894A (ja) | 2007-12-20 |
US20070141573A1 (en) | 2007-06-21 |
AU2004242759A1 (en) | 2004-12-09 |
DE602004020334D1 (de) | 2009-05-14 |
ATE427356T1 (de) | 2009-04-15 |
NZ544163A (en) | 2009-06-26 |
MXPA05012880A (es) | 2006-02-22 |
ES2324993T3 (es) | 2009-08-21 |
EP1629098A2 (en) | 2006-03-01 |
US7884188B2 (en) | 2011-02-08 |
US8993264B2 (en) | 2015-03-31 |
US9834585B2 (en) | 2017-12-05 |
BRPI0410876A (pt) | 2006-07-04 |
US20110263482A1 (en) | 2011-10-27 |
AU2004242759B2 (en) | 2009-11-26 |
WO2004106369A2 (en) | 2004-12-09 |
US20180127472A1 (en) | 2018-05-10 |
CA2526083A1 (en) | 2004-12-09 |
HK1085511A1 (en) | 2006-08-25 |
US20220363726A1 (en) | 2022-11-17 |
CA2526083C (en) | 2017-01-17 |
EP1629098B1 (en) | 2009-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B25G | Requested change of headquarter approved |
Owner name: EVOLUTEC LIMITED (GB) |
|
B25A | Requested transfer of rights approved |
Owner name: VARLEIGH LIMITED (GB) |
|
B25D | Requested change of name of applicant approved |
Owner name: VARLEIGH IMMUNO PHARMACEUTICALS (VIP) LIMITED (VG) |
|
B25G | Requested change of headquarter approved |
Owner name: VARLEIGH IMMUNO PHARMACEUTICALS (VIP) LIMITED (VG) |
|
B25A | Requested transfer of rights approved |
Owner name: VOLUTION IMMUNO PHARMACEUTICALS SA (CH) |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 03/11/2020, OBSERVADAS AS CONDICOES LEGAIS. |
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B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/06/2004 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
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B16B | Notification of grant cancelled [chapter 16.2 patent gazette] |
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